1.1 overview of the nephron Flashcards
What substances are filtered at the kidney?
Water Sodium Chloride Potassium Bicarbonate Amino acids Glucose Creatinine Urea
How much of the blood flowing through the glomerulus is filtered?
20%
What substances are secreted into the proximal convoluted tubule?
Uric acid
Organic acids
What substances are reabsorbed in the PCT?
Potassium Sodium Chloride Amino acids Glucose Bicarbonate Water
What substances are completely reabsorbed at the PCT?
Amino acids
Glucose (if below threshold)
What is reabsorbed in the descending limb of the loop of henle?
Water
Why are the kidneys very susceptible to ischaemic damage?
As the renal arteries receive 20-25% of all CO.
What is reabsorbed in the ascending limb of the loop of henle?
Sodium
Chloride
Where does aldosterone work?
In the DCT
What is secreted into the DCT?
Potassium
Hydrogen ions
What is reabsorbed at the DCT?
Sodium
Chloride
Water
What is clearance?
The rate that the kidney filtrate is removed from the blood at the bowmans capsule
What is reabsorbed at the collecting duct?
Urea
Sodium
Chloride
Water
Where does ADH work?
Collecting duct
What is excreted in urine?
- Water
- Na+ (<1%)
- Cl-
- HCO3-
- Creatinine
- Urea
