11 - Mechanisms of Protein Action Flashcards
1
Q
what are the 7 mechanisms that control proteins action?
A
expression/degrad effective ligand binding ph interaction domains localisation protein switches protein modifications
2
Q
expression and degrad?
A
- control transcription [amount] and lifetime in cell
level control - transcription
lifetime - degradation
3
Q
effective ligand binding?
A
binding of molecule
cause confor change
either activates or inhibits
4
Q
ph?
A
changes state of ionizable groups
5
Q
interaction domains?
A
proteins have multiple domains
control interatcions with other mols
or domains can interact by intramolecular bonds
6
Q
localisation?
A
controlling where the protein is in the cell
7
Q
protein switches?
A
turning on or off as proteins aren’t always needed
protein switches usually are enzymes
8
Q
protein mods?
A
increases complex
