11/6 Reflexes Flashcards

1
Q

What is a spinal cord reflex?

A

a rapid involuntary predictable motor response to a stimulus. it is unlearned, unpremeditatied and involuntary.

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2
Q

what is the role of reflexes?

A

to aid in posture, and to help prevent injury

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3
Q

Why would we use reflexes clinically?

A

to localize and characterize a neurologic leasion.

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4
Q

what is an arrangment of neurons and their synaptic connections in a region of the brain?

A

local circuit.

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5
Q

how can we break down the organization of the brain to individual “modules”

A

Local circuits that are interconnected and nearly modular, and composed of microcircuits that are then made up of individual synapses, memebranes, and molecules, ions and the genes that encode and control the system’s molecularbiology

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6
Q

what war the three elements of most local circuits?

A

input axons, interneurons (both excitatory and inhibitory), and projection or output neurons.

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7
Q

What are the components of a reflex arc?

A
  1. Receptor; 2. Sensory neurons; 3. Integration center (interneuron); 4. Motor neuron; 5. Effector
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8
Q

What is a stretch reflex?

A

a skeletal muscle is stretched passively, and the reflex is to contract the same muscle and relax the antagonist.

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9
Q

Examples of stretch reflexes

A

Myotactic reflex, tendon reflex, patellar reflex, knee-jerk reflex

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10
Q

what is a myotatix reflex?

A

a reflex that is characterized by only one synapse between a sensory cell and motor neuron: the most basic reflex!

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11
Q

Why would we even have stretch reflexes?

A

they provide the NCS with motor control postural control and muscle tone info. detect muscle lenght and rate of change, oppose stretch, etc.

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12
Q

what is a motor unit?

A

a single motor (alpha) neuron and the muscle cells that it synapes.

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13
Q

contrast the size of motor units and the function of muslce

A

the smaller finer control muscles are composed of smaller motor units this can vary from a few to thousands of muscle fibers.

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14
Q

what is the point at which neurons connect to muscle fibers called?

A

the neuromuscular junction.

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15
Q

what are the two types of motor neurons?

A

Alpha and Gama

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16
Q

what are alpha motor neurons?

A

they innervate the main force-generating muscle fibers (the extrafusal fibers)

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17
Q

what are gama motor neurons?

A

they innervate only the fibers of the muscle spindles (intrafusal fibers)

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18
Q

what is the major method of increasing the strength of contration of skeletal muscles>

A

it is recruitment (of more muscle units).

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19
Q

what is a muscle spindle?

A

it is a small spindle-shaped emcapsulated structure oriented parallel to muscle fibers and scattered throughout muscle.

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20
Q

what is the purpose of muscle spindles?

A

they are mechanosensitive propriceptors. or they sense the relative position of neighboring parts of the body and strength of effort involved in movement.

21
Q

what happens physically to a spindle when the muscle moves?

A

the muscle spindle is stretched when the muscle is stretched: the spindles are about 20% of the length of the fibers and 20 to 100s per muscle.

22
Q

where could we find the greatest number of muscle spindles?

A

in fine control muscles (hands etc.)

23
Q

what are the motor and sensory nerve fibers to the muscle spindles (intrafusal muscles fibers)

A

The motor: Gamma efferent motor fibes; Sensory: Secondary sensory endings (type II fibers), and Primary sensory endings (type Ia fibers)

24
Q

What is the function of the two types of muscle spindle sensory fibers?

A

Secondary sensory: detect amount of stretch; Primary sensory: Detect rate and amount of stretch

25
Q

describe the appearence of the sensory fibers on the muscle spindles:

A

the secondary sensory ending are nerve fibers that simple synapse at both ends of the muscle spindle (sense the stretch by measuring the change in that distance); The primary sensory endings are wrapped around and around the spindle from the top to the bottom. (sense the stretch and rate by sensing the thickness of the spindle)

26
Q

How does the primary or 1a sensory fiber detect the length and rate of stretch?

A

they are wrapped around the muscle, and as the muscle stretches, mechanosensitive receptors depolarize sensory endings in response to stretch, and the 1a firing rate is proportional to stretch: High stretch=high firing rate; low stretch= low firing rate

27
Q

how do the gamma neurons and alpha neurons respond to the 1a and type II neurons?

A

the gamma neurons respond to the Ia fiber firing rate to maintain the length of the spindle fiber in order to maintain the sensitivity of the spindle fiber. The Ia fiber can go to the spinal chord and synapse with inerneruons or directly with alpha neruons to cause alpha neuron action!!

28
Q

what is the mathmatical relationship between 1a sensory fiber firing rate and the stretch of the muscle?

A

they are directly proportional.

29
Q

what is a myotatic reflex

A

a stretch reflex that is to the same muscle that is stretched.

30
Q

why would the z bands of a spindle muscle fiber only be at the ends of the fiber?

A

the ends are the only part that contract, therefore the contraction of the muscle (gamma neurons) also causes the stretch of the fiber and can cause greater sensitivity of the spindle fiber to stretch!

31
Q

how does a stretch reflex work…..?

A

stretching the muscle stimulates the spindle afferents, i.e. the 1a axon. In the spinal cord the 1a axons terminate monosynaptically onto the alpha motor neurons that innervate the same muscle, thus stretching of a muscle causes rapid feedback excitation of the same muscle through the minimum possible circuit: one sensory neuron, one synapse, and one motor neuron. (there is no interneuron=only one synapse), at the same type through a interneuron the antagonist muscle is also inhibited. (reciprocal innervation)

32
Q

Why do we even have these reflexes?

A

important for maintain muscle tone and adjusting reflexively and important for maintaing posture!

33
Q

How can we excite a muscle spinde?

A

Two ways: 1. stretch the muscle: extra and intrafusal muscle lengthing due to relaaxation of muscle or contraction in antagoistic muscle. 2. Gamma fiber signaling: evoked intrafusal stretch (this occurs during voluntary contraction and loading of the muscle!!

34
Q

how can the brain use the spindles to control the tone of muscles and smoothness of contraction in a wide variety of different situations?

A

Gama fibers allow for the contraction of the spindle fibers and this will increase or decrease the sensitivity of the unit to stretch and therefore provide control in a variety of situations!

35
Q

what if I lose either the efferent or and afferent nerves to the muscle spindles?

A

then the muscle is immediately flaccid – loses its tone!

36
Q

how can we contract the muscle and maintain sensitivity on the muscle spindle?

A

the alpha and the gamma fibers are activated at the same time and this will shorten the muscle spindles and lead to shortening of the muscle spindle and make it more sensitive to the shortened length of the muscle.

37
Q

Why would we need to maintain the sensitivity of the musle spindles through the use of the Gamma fibers?

A

to maintain a good control and posture in contraction situations!

38
Q

what is a golgi tendon reflex?

A

The golgi tendon reflex is a counter reflex to the stetch reflex – it will act to loosen the muscle under stetch in order to prevent damage to the muscle!

39
Q

what is a golgi tendon organs?

A

they are in the ends of the tendon, where there are encapsulated sense organs in series with the muscle fibers, about 10 to 15 muslce fibers connected to each golgi tendon organ. they have 1b afferent neurons that send info on the stretch of the tendon and the muscles connected to it!

40
Q

what is the purpose of the golgi tendon organs?

A

they sense the load or the stretch on the muscles and send inhibitory signals to stop the over stretch of the muscle: protect the muscle! It can therefore control the group of muscle to make sure that it is evenly being contracted as well.

41
Q

contrast the stretch and golgi reflex

A

it is the opposite of the stretch reflex! opposes muscle contraction through inhibition of motro nerons causing relaxation. golgi is anti alpha neurons and stretch is pro alph!

42
Q

Besides preventing the tearing of muscle fibers what else do golgi fibers seem to do?

A

they can balance a muscle load by balancing the stretch between different groups of muscle fibers.

43
Q

Describe the circuit of nerves for the Golgi reflex

A

the gogli tendon organ senses stetch and sends signal down Ib neuron that goes to dorsal root and the spinal chord to synapse with interneurons that then synapse with alpha motor neurons to inhibit the contracting muscle and activate the non-contracting muscle.

44
Q

what the what…golgi and stretch oppose each other how can we get anything done?

A

the amplitude and sensitivity of the relfexes is extensively modulated by descending input form the upper motor neurons. the two reflexes send signals to the higher motor control centers, an help provide smooth muscle movement.

45
Q

What is the Flexor-withdrawl/flexor and crossed-extensor/flexor reflex?

A

occurs with pain, tactile or noxious stimulus. cause withdrawl of affected side and extension of the opposite side (i.e. step on a tack)

46
Q

describe the circutei for a flexor and crossed extensor reflex

A

the afferent fiber neuron will synapse with interneurons on both sides of spinal chord to lead to withdrawl of body on one side and extension on the other.

47
Q

Waht are superficial reflexes?

A

they are triggered by gentle cutaneous stimulation of the skinn or mucous membranes.

48
Q

waht is the plantar reflex?

A

normal response to L4-S2 stimulation on the foot is to flex toes, the abnormal is to extend toes (babinski relfex)

49
Q

when a muscle is suddenly stretched, a signal is transmitted over 1a sensory fibers from muscle spindles. describe the response elicited by these spindle afferent signals

A

Contraction of the muscle in shich the ative spindles are located. When a muscle is stretched, signals traveling over Ia sensory fibers will lead to contraction of the muscle in which the ative spindles are located. at the same time, the antagonist muscles will be inactivated. the intrafusal fibers in the spindle do not go slack due to the tonic activation of gamma motor neurons by supraspinal system.