11 Flashcards

1
Q

Treatment of nongonococcal urethritis (watery discharge, dysuria, absence of bacteria)

A

azithromycin or doxycycline if chlamydial
if these don’t respond, then try metronidazole as it can be trichomonas
(**ceftriaxone for gonococcal urethritis)

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2
Q

Gold standard test for HIT, and when to start warfarin in HIT

A
  • serotonin release assay

- after treatment with non-heparin anticoagulant and platelet counts improving upto >150,000

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3
Q

Treatment of HELLP (hemolytic anemia, elevated liver enzymes, low platelet count) syndrome in severe pre-eclampsia

A

magnesium sulfate infusion

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4
Q

Diagnostic test to confirm organophosphate poisoning

A

RBC cholinesterase activity test

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5
Q

Reactive arthritis (asymmetric oligoarthritis, uveitis, urethritis, keratoderma blenorrhagica), usually occurs after genitourinary/GI infection, diagnostic test?

A
  • synovial fluid shows elevated WBC but no bacterial culture
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6
Q

Treatment of iodine induced thyrotoxicosis (extreme fatigue, weight loss, palpitations after imaging)

A
  • usually self limiting
  • beta blockers for mild symptoms
  • antithyroid drugs for moderate to severe sx
  • potassium perchlorate for refractory cases
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7
Q

Management of flail chest ( tachypnea, tachycardia, shallow breathing, inadequate ventilation, double rib fx in more than one site, paradoxical/segmental chest movement )

A
  • oxygen
  • pain control
  • positive pressure ventilation
  • surgical stabilization
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8
Q

Treatment of mild to moderate psoriasis? psoriatic arthritis (DIP involvement, presents a lot like RA otherwise)?

A
  • topical glucocorticoids or vitamin D derivatives (calcipotrieine)
  • if systemic, need methotrexate
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9
Q

when to give oral metronidazole vs oral vanc for c.diff. When do you give IV metronidazole?

A
  • give oral vanc if WBC >15000, creatinine greater than 1.5x of baseline, or serum albumin <2.5 or temp >100.9
    If there is ileus, then give IV metronidazole or rectal vanc
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10
Q

Centor criteria for streptococcal pharyngitis: strep testing recommended if two or more criteria met, but if one or no criteria met, then sx treatment and no test

A
  1. tonsillar exudates
  2. tender anterior cervical lymphadenopathy
  3. fever
  4. absence of cough
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11
Q

Treatment for toxic megacolon

A
  • in presence of pneumoperitoneum: surgery
  • in absence: steroids if negative for c.diff, and appropriate abx
  • avoid 5 ASA and opioids
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12
Q

Asymmetry in a funnel plot suggests what kind of bias?

A

publication bias

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13
Q

Screening test for hemochromatosis ( central hypogonadism, liver dysfunction, DM, arthropathy, skin pigmentation, hook-like osteophytes on x-ray)? Gold standard?

A
  • serum iron studies- transferrin saturation

- gold standard: liver biopsy

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14
Q

Managing sexual SE related to SSRI (decreased libido, delayed ejaculation etc)

A
  • switch to mirtazapine or buproprion

- adjunctive therapy with sildenafil

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15
Q

Complications of MI

A
  • acute pericarditis (1-4 days): pericardial friction rub, pain changes with position and deep inspiration
  • chordae tendinae (2-7 days): acute hemodynamic instability, pulmonary edema
  • dressler’s syndrome (weeks to months): autoimmune mediated syndrome, fever, leukocytosis, pleuritic chest pain, pericardial rub
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16
Q

Treatment of acute pericarditis

A

high dose aspirin, close obs

17
Q

Initial management of postpartum hemorrhage (mostly caused by uterine atony)

A
  • fundal massage
  • uterotonic medications-oxytocin
  • fluid resuscitation
  • transfusion
    • if none of these help, then US, etc
18
Q

Best lab test to assess thyroid function after RAI treatment?

A

total T3 and T4 levels

19
Q

Abnormal lab levels associated with TURP

A

hyponatremia

20
Q

Contraindications of vaccines in HIV patients

A
  • live vaccines (MMR, zoster, varicella) are contraindicated if CD4 counts <200.
21
Q

Clinical features of acute retroviral syndrome/ HIV infection

A
  • thrombocytopenia, leukopenia
  • low grade fever, fatigue, maculopapular rash on face, trunk, extremities
  • headache, lymphadenopathy, pharyngitis
  • myalgias, arthralgias
  • GI sx, night sweats, oral ulcers/thrush
22
Q

Clinical features of subacute thyroiditis (inflammatory damage to thyroid follicles lead to release of stored thyroid hormones) and diagnostic testing, treatment?

A
  • fever, hyperthyroidism sx
  • painful, tender goiter
  • elevated ESR and CRP
  • low radioiodine uptake
  • treatment: supportive, NSAIDs and beta blocker
23
Q

most common causes of fever of unknown origin

A
  1. connective tissue disease
  2. infectious disease
  3. malignancy
24
Q

Management of acute back pain

A
  1. no red flags, sciatica or cord compression: conservative therapy
  2. red flags or sciatica/no improvement from PT: x-ray and ESR
  3. cord compression/abnormal x-ray and ESR: MRI
25
Q

Clinical features of MS and diagnosis test?

A
  • optic neuritis (monocular vision loss and pain)
  • transverse myelitis (UMN signs below lesion)
  • internuclear ophthalmoplegia, numbness, parthesia, heat sensitivity, motor paraparesis, bowel/bladder dysfx
  • diagnostic test: MRI (periventricular white matter region), lumbar puncture (oligoclonal bands or increased IgG) if equivocal
26
Q

Treatment of MS, in presence of optic neuritis? chronic management meds? MS related fatigue?

A
  • IV corticosteroids, as oral can promote recurrent optic neuritis
  • plasmapheresis if refractory to steroids
  • chronic management: disease modifying drugs– beta interferon, glatiramer acetate
  • MS related fatigue: amantadine
27
Q

Clinical features of Addison’s disease/adrenal insufficiency, diagnostic test

A
  • weight loss, abdominal pain, asthenia
  • decreased axillary and pubic hair
  • increased pigmentation
  • muscle tenderness
  • hyponatremia, hyperkalemia, hyperchloremic metabolic acidosis
  • ddx test: cosyntropin (synthetic ACTH) test with cortisol and ACTH levels
28
Q

Hyperaldosteronism (hypertension, hypokalemia, metabolic alkalosis) diagnostic test and treatment

A
  • ddx: low renin, hypertension, elevated aldosterone level. Confirm with CT scan of adrenal glands
  • treatment: solitary adenoma– surgical resection
    hyperplasia– spironolactone
29
Q

Congenital adrenal hyperplasia has what lab characteristics, treatment?

A
  • elevated ACTH
  • low aldosterone and cortisol levels
  • tx: prednisone
30
Q

Paget’s bone disease (pain, stiffness, aching, fx, bowing of the tibias, osteolytic lesion, normal calcium and phosphate levels) treatment and diagnostic test

A
  • tx: bisphosphonates (alendronate) and calcitonin
  • best initial test: alkaline phosphatase level
  • most accurate test: x-ray