1 Flashcards

1
Q

Features of tabes dorsalis

A
  • neurodegenerative condition that interferes with posterior spinal column and nerve roots
  • treponema pallidum infx
  • argyll robertson pupils (normal pupillary constriction w/ accomodation but not w/ light)
  • sensory ataxia
  • lancinating pain
  • neurogenic urinary incontinence
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2
Q

late dementia is associated with what dz

A

alzheimers and vascular dementia

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3
Q

budd chiari syndrome signs sx tx

A
  • ascites on imaging
  • severe abdominal pain
  • hepatic vein obstruction usually from thrombosis
  • young and middle aged women
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4
Q

acute hep b treatment

A
  • supportive measures, unless infected with concurrent hep c, immunosuppression, or severe disease
  • then, requires antiviral therapy
  • hep b ig and hep b vaccine usually given within 24 hours postexposure
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5
Q

acute to chronic hepatitis progression rates

A
  • if perinatally acquired, then 90%
  • for hep b, 5% of adults get chronic
  • for hep c, 50%
  • infected at age 1-5, 20-50% rate
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6
Q

Causes of long QT syndrome

A
  • meds (diuretics, anti-emetics, anti-psychotics, TCA, SSRI, antiarrthymics, antianginal drugs, anti-infective drugs)
  • metabolic disorders (electrolytes, hypothyroidism)
  • bradyarrhythmias (SA node dysfx, AV node)
  • Others (infection, hypothermia, MI)
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7
Q

torsades de pointes treatment

A
  1. IV mag

2. temporary transvenous pacing

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8
Q

Acute mitral regurgitation causes, sx, heart sound, diagnostic test

A

causes: mitral valve prolapse, IE, trauma, rheumatic heart dz
- sx: pulmonary edema, cardiogenic shock, pulm HTN–> right heart failure
- descrescendo systolic murmur, silent murmur 50% of the time
- need ECHO

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9
Q

Ehlers Danlos syndrome

A
  • joint hypermobility
  • velvety hyperextensible skin
  • atrophic scars
  • AD
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10
Q

Marfan’s syndrome

A
  • pectus carinatum
  • increased arm span to height
  • aortic root dilation, MVP
  • lens dislocation
  • spontaneous pneumothorax
  • AD
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11
Q

Refeeding syndrome clinical fx

A
  • arrhythmia
  • CHF (pulmonary edema, peripheral edema)
  • seizures
  • wernicke’s encephalopathy
  • decreased phos, potassium, mg, thiamine, increase in sodium, water retention
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12
Q

hyperthyroidism treatment

A
  • beta blockers if symptomatic
  • methimazole, PTU if thyroid storm (fever, AMS, CHF, liver disease)
  • surgery/RAI if oral drug therapy fails
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13
Q

thyrotoxicosis in elderly

A
  • neuro: apathy, confusion, tremor, proximal muscle wasting
  • CV: afib, tachycardia, HF
  • endocrine: proptosis, lid lag, thyromegaly (often absent)
  • GI: decreased appetite, constipation
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14
Q

suicide assessment

A

ideation, intent, plan

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15
Q

when to start antivirals for flu (ostelmavir)

A
  • hospitalization
  • less than 48 hours of sx onset
  • age over 65 or pregnant
  • other high risk medical condition; pulmonary, cardiac
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16
Q

Indications for stress ulcer prophylaxis (PPI)

A

any 1 factor:

  • coagulopathy (low platelets, high INR etc)
  • mech vent > 48 hours
  • GI bleeding/ulceration in the past year

any 2 factors:

  • sepsis
  • 1 week ICU stay
  • glucocorticoid therapy
  • occult GI bleeding > 6 days
17
Q

presentation of acute ischemic colitis

A
  • pt usually has atherosclerotic disease
  • abdominal pain followed by bloody diarrhea (splenic flexure or rectosigmoid jx)
  • x-ray/sigmoidoscopy show mucosal edema or mucosal ulceration
18
Q

How to assess HIV progression

A
  • CD4 count: damage that has already occurred

- viral load: disease activity/ damage that is about to occur

19
Q

when to start statin therapy

A
  • atherosclerotic disease
  • LDL >190
  • age 40-45 w/ diabetes
  • estimated 10 year ASCVD risk >7.5%
20
Q

management of symptomatic PAD

A
  1. risk factor management: start statin, antiplatelet therapy, bp, diabetes, smoking cessation
  2. exercise program
  3. meds: cilostazol
  4. revascularization (stents, surgery)
21
Q

management and treatment of familial adenomatous polyposis (FAP)

A
  • colectomy
  • need upper GI endoscopy to see if gastric and duodenal adenomas/carcinomas exist
  • nearly all patients get Colon CA by age 45
22
Q

management and treatment of acute pancreatitis

A
  • check amylase and lipase levels
  • look for etiology: lipid test, US for gallstones, calcium levels
  • treat with IV fluids (third spacing), pain control
  • acute pancreatitis with deterioration after 72 hours needs CT SCAN
23
Q

when should wounds be left open?

A
  • puncture wounds

- dog bite, cat bite, human bite hand injury

24
Q

neonatal jaundice presentation normal vs abnormal

A
  • physiologic jaundice presents 24 hours after birth
  • coombs negative unconjugated hyperbili in first 24 hours represents hemolysis (G6PD in Af. Am, Mediterranean, Asian male infants as it is X-linked)
25
Q

HIV treatment in 6 months in treatment naive pt makes how many viral load?

A

<50 copies

26
Q

best test for subphrenic abscess?

A

abdominal ultrasound

  • presents with swinging fever, leukocytosis and follows abdominal surgery
27
Q

Characteristics of porphyria cutanea tarda

A
  • associated with Hep C infx
  • painless blisters
  • hypertrichosis
  • hyperpigmentation
28
Q

most effective oral contraceptive?

A
  • ulipristal- upto 5 days after unprotected sex

- copper IUD is most effective but contraindicated in acute cervictitis/pelvic infx/ wilson’s disease

29
Q

empiric abx treatment for sexual assault

A

ceftriaxone (gonorrhea)
azithromycin (chlamydia)
tenofovir-emtricitabine with raltegravir (HIV)
metronidazole (trichomonas vaginalis)

30
Q

How does fat embolism present?

A
  • 24-72 hours after severe trauma
  • triad of respiratory insufficiency, neurologic impairment, petechial rash
  • early immobilization and operative fixation of fx reduces its occurrence