1030- Protein sorting and trafficking

Question 1

The cytoplasmic pathway for completely folded proteins

Answer 1

proteins are formed from the MRNA and cytoplasmic ribosome , the completely folded proteins then go to either the peroxisome , act as a cytoplasmic protein or is transferred to the nucleus.

Question 2

The cytoplasmic pathway for completely unfolded proteins

Answer 2

transferred to the mitochondria to be folded up .

Question 3

ER signal sequence

Answer 3

Originally there is an ER signal sequence attached to a protein inside the ER and there is a cytoplasmic protein outside the ER. The signal sequence then attaches itself to the protein in the ER.

Question 4

What is the 2 destinations of formed proteins in the ER.

Answer 4

Proteins are either transported to the cell membrane to be a membrane protein or the protein is transferred to other vesicle components of the cell.

Question 5

What protein modifications occur in the ER

Answer 5

Protein folding, Formation of disulphide bonds, glycosylation bonds.

Question 6

Function of glycosyltransferases

Answer 6

Enzymes which add sugars to proteins.