1020 MODULE 3 THE CELL Flashcards
Golgi apparatus
responsible for packaging proteins from rough ER to membrane-bound vesicles
- contains two vesicles produced by Golgi bodies
1. Secretory vesicles: transports proteins into the cell membrane
2. Storage vesicles: contains contents of lysosomes
Ribosomes
responsible for manufacturing proteins from amino acids under the control of the cell’s DNA
- fixed ribosomes fixed to er and makes proteins
free ribosomes- float in cytoplasm
lysosome
- are a type of storage vesicle produced by Golgi bodies
- have enzymes used to destroy the damaged organelles
Mitocondria
- produces ATP
-powerhouse of the cell
Endoplasmic Reticulum
- site for the synthesis, packaging and transporting of proteins and lipids
rough er- site for protein synthesis
smooth er- site for lipid synthesis because it lacks ribosomes and ribosomes are responsible for manufacturing proteins from amino acids under control of DNA
Cell membrane
- is selectively permeable
-regulates the transport of substances in and out of the cell
Centriole
- directing the movement of DNA strands during the process of cell division
Nucleolus
contains DNA for producing RNA found in ribosomes
What can penetrate the cell membrane
molecules and ions
What cannot penetrate the cell membrane
proteins, nucleotides, and other large macromolecules
Phospholipid
- the phospholipid molecule is made up of a hydrophobic lipid and fatty acid tail and a hydrophilic phosphate head.
- when thrown in the water, the tail goes in and aligns itself since it is hydrophobic and the heads are towards the outside.
- then this creates a lipid bilayer
-this is why some water and water-soluble particles cannot get in like ions or glucose but fat-soluble substances like o2 and co2 can get in.
Membrane proteins
- receptors- attachment of chemical hormones and neurotransmitters
- Enzymes- chemical reactions help with the breakdown of molecules
- Ion channels- help water-soluble substances to go in
- membrane transport- transport of molecules across cells
- Cell identify markers- antigens like foreign particles that stimulate immune system
Most important function of proteins
helps transport substances across the membrane
Different ways to cross membranes
- facilitated diffusion
- active transport
- diffusion through protein channels
-diffusion through lipid bilayer
-endo and exocytosis
Facilitated diffusion
- the movement of specific molecules across the membrane through protein channels
does not require ATP because it is moving down the concentration gradient
Facilitated diffusion continued.
- water- soluble large substances cannot pass through or diffuse through the lipid bilayer.
-they are also too large to pass through the protein channel. - this specific molecule attaches itself onto the protein channel and forces it to change the shape which initiates the opening of the channel
How does facilitated diffusion differ from simple diffusion
- it differs because unlike simple diffusion, the rate of transport is limited due to the number of protein channels
Active transport
- the movement of specific molecules across the cell membrane through protein channels.
- this requires ATP because the molecules are moving against the concentration gradient so low to high.
ex sodium-potassium pumps
Diffusion of a water-soluble substance through membrane requires what?
pore, channel, concentration gradient
Rate of movement of molecules through protein channels are limited by what factors
- the size of the protein channel
- greater the electrochemical gradient
- number of cell membrane
- the charge on the molecule
recallll process of facilitated diffusion
- protein binds with a molecule
- the shape of protein channel changes
- molecule moves across the membrane
Osmosis
- the movement of water from high to low concentration so down the concentration gradient
What factors affect osmosis across the cell membrane
- pressure gradient
- the concentration gradient of solute in intercellular and interstitial
- the permeability of the membrane to solute in intercellular and interstitial
what particle causes osmosis
osmotically active particle
Tonicity
the ability of the solution to cause cells to lose or gain water SO CAUSE OSMOSIS
Isotonic
concentration in and out the cell is the same
Hypotonic
- low concentration than cellular fluids
- will cause osmosis in the cell and swell
Hypertonic
- high concentration than cellular fluids
- causes osmosis to exit and shrink
types of membrane potentials
- equilibrium potential
- action potential
-resting membrane potential
what is membrane potential
the ionic charge difference in and out the cell
equilibrium
2 factors
concentration gradient and electrical concentration gradient
- when the forces are equal in magnitude and opposite in direction, then there is no net movement
resting membrane potential
cells potential at rest
action potential
cells potential in action
different resting - equilibrium potentials
- Na+ +60 mV
- K+ -90mV
- Cl -70mV
- resting membrane potential = -70 mV
Functions of the Sodium- Potassium Pump
- to balance equilibrium and 3 Na will try to get out and 2 K will get in