10.2 Random donor and Single Donor platelets

Question 1

To correct thrombocytopenia due to decreased platelet function, decreased platelet production, or increased platelet consumption

a. Random donor platelets
b. Single donor platelets

Answer 1

a

Question 2

Each unit of the Random donor platelet concentrate should increase the platelet by _______________

Answer 2

5000 - 10000/uL

Question 3

How many units of platelet concentrate are required to have a therapeutic effect?

Answer 3

6-8

Question 4

What is the advantage of RDP concentrate?

Answer 4

Cheaper

Question 5

What is the major disadvantage of Random donor platelet?

Answer 5

Exposed to several foreign antigen

Question 6

To correct thrombocytopenia due in patients who demonstrates refractoriness

a. Random donor platelets
b. Single donor platelets

Answer 6

b

Question 7

Single donor platelets increase platelet count by?

Answer 7

20000 - 60000

5000 - 10000 for Random donor platelet

Question 8

Platelet concentrate for RD:

Shelf life?

Answer 8

<5 days

Question 9

Platelet concentrate for SD:

Shelf life?

Answer 9

5 days

Question 10

Platelet concentrate for RD:

Storage temp?

Answer 10

20-24 C same with SD

Question 11

Platelet concentrate for RD:

Quality control

Answer 11

> 5.5 x 10^10

Question 12

Platelet concentrate for SD:

Quality control

Answer 12

> or equal to 3.0 x 10^11

Question 13

Platelet concentrate for RD:

pH?

Answer 13

6.2 same with SD