Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Hematology > 10.12.18 Ehrilichiosis/Anaplasmosis > Flashcards

10.12.18 Ehrilichiosis/Anaplasmosis Flashcards

(45 cards)

Start Studying
1
Q

What are bacteria diseases and vector?

A

Ehrlichiosis, Anaplasmosis

Tick

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are protozoa diseases and vectors?

A

Leishmaniasis, Trypanosomiasis

Sand fly, Tsetse fly/Reduvlid bug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Human diseases with an animal reservoir

A

Zoonoses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the cycle of vector-borne transmission?

A
  1. Infected host
  2. Intrinsic incubation period
  3. Infectious host
  4. Vector
  5. Extrinsic incubation perion
  6. Infectious vector
  7. Grace period
  8. Humans
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Infects monocytes and causes human monocytic ehrlichioisis (HME)

A

Ehrlichia chafeensis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

infects granulocytes and causes human granulocytic anaplasmosis (HGA)

A

Anaplasma phagocytophilum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Infect red blood cells and liver cells

A

Malaria species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Infects RBC

A

Babesia microti

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Infects monocytes and macrophages

A

Trypanosoma species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Infect macrophages and reticuloendothelial cells

A

Leishmania species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which obligate intracellular pathogen infects monocytes?

A

Ehrlichia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which obligate intracellular pathogen infects neutrophils?

A

Anaplasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What family do Ehrlichia and Anaplasma belong to?

A

Rickettsiae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

infects endothelial cells and causes Rocky Mountain Spotted Fever

A

Rickettsia Rickettsii

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where does Ehrlichia chaffeensis infect, when, and what are the risk factors?

A
  1. Southeast to South central US
  2. Spring and Summer
  3. Hiking, Exposure to Wildlife
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the vector, animal reservoir, and other routes of transmission for ehrlichia chaffeensis?

A
  1. Tick
  2. White tail deer, dogs, coyotes
  3. Maternal child, blood transfusion, contact with slaughtered deer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What would you see in blood smear with human monocytic ehrlichiosis?

A

Monocyte with characteristic morulae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

How would you diagnose human monocytic ehrlichiosis?

A
  1. Indirect fluorescent antibody (IFA)
  2. Peripheral blood
  3. PCR
  4. Immunochemical staining in tissues
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What does anaplasma phagocytophillium infect?

20
Q

Where does anaplasma phagocytophillium infect, when, and what are the risk factors

Study These Flashcards
A
  1. Upper midwest and northeast US
  2. Spring and summer (can be all year)
  3. Hiking, Exposure to wildlife
21
Q

Which bacteria has a high seroprevalence so its likely there are lots of asymptomatic transmission?

Study These Flashcards
A

Anaplasma phagocytophillium

22
Q

What is the vector, animal reservoir, and other routes of transmission for anaplasma phagocytophillium?

Study These Flashcards
A
  1. Tick
  2. Deer, Rodents/small mammals
  3. Person-to-person, blood transfusion, Nosocomial
23
Q

How would you diagnose human granulocytic anaplasmosis?

Study These Flashcards
A
  1. Morulae in PMN
  2. PCR
  3. Serology
24
Q

What are the clinical signs and symptoms of ehrlichioisis and anaplasmosis?

Study These Flashcards
A
  • Asymptomatic to chronic infection

- Typically acute febrile illness

25
Which bacteria is more life threatening?
Anaplasmosis
26
What is the treatment for ehrlichiois and anaplasmosis?
Use antibiotics early with suggestive clinical presentation Specifically Doxycycline/Tetracycline because it can get inside cells
27
Motile, feeding, reproducing forms of protozoa
Throphozoites
28
Flagellated forms of protoazoa
-mastigotes
29
Sexual stages of protoazoa
1. Merozoites 2. Schizonts 3. Gametes 4. Oocysts
30
Where is Babesiosis (Babesia microti) found and what are risk factors?
Northeast and upper midwest Hiking, Exposure to wildlife
31
What is the vector, animal reservoir, and routes of transmission for babesia microti?
Tick White-footed mice Blood transfusion, congenital (rare)
32
What are the clinical manifestations of babesiosis?
- Asymptomatic or flu like - Dark urine/hemolytic anemia - Life threatening in 1. Patients w/o spleen 2. Immunocompromised 3. Advanced age
33
How can you diagnose Babesia?
1. Merozoite tetrad in blood smear (can be difficult to distinguish from plasmodium) 2. Serology (IFA) 3. PCR
34
What are two different types of Leishmaniasis?
1. Visceral leishmaniasis | 2. Cutaneous and mucocutaneous leishmaniasis
35
- Intracellular pathogens of the macrophage - Sand fly insect vector - Diverse group of protozoan parasites
Leishmaniases
36
What is the vector, animal reservoir, and other routes of transmission for Leishmaniasis?
Female sand flies Small rodents/other mammals; human reservoir in some regions Blood transfusion, IV Drug use, Needle sharing, Congenital
37
What are the clinical manifestations for leishmaniasis?
1. Fever 2. Weight loss 3. Swelling of spleen and liver 4. Anemia 5. Fatality 6. Post-kala-azar manifestations
38
How do you diagnose leishmaniasis?
1. Bone marrow/splenic aspirate to detect amastigotes in macrophage 2. Serology
39
What does each amastigote in Leishmania have?
1. Nucleus | 2. Kinetoplast- rod shaped
40
What is another term for African trypanosomiasis and what causes it?
Sleeping sickness T. Brucei
41
What is another term for American trypanosomiasis
Chagas disease T. Cruzi
42
What is the vector, animal reservoir, and other routes of transmission for chagas disease?
Reduviid bug- bites then poops Aramadillos, raccoons, dogs, guinea pigs, rats Blood transfusion, congenital
43
What are clinical manifestations for chagas disease?
Asymptomatic or flu like Classic Romana's sign- swelling of eyelids May develop myocarditis; death due to cardiac pathology
44
How do you diagnose chagas disease?
1. Blood smear to detect extracellular trypomastigotes in acute infection 2. Bone marrow aspirate or muscle biopsy to detect intracellular amastigotes in chronic infection 3. Serology
45
What is the vector for T. Brucei?
Tsetse fly

Hematology (23 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions