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PPE > 10.1 Anti-arrhythmics > Flashcards

10.1 Anti-arrhythmics Flashcards

1
Q

What do Class 1 anti-arrhythmics do?

Examples?

A

Block Na+ Channels
Procainamide
Lidocaine
Fleconide

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2
Q

What do Class 2 anti-arrhythmics do?

Examples?

A

Beta Adrenoceptor Antagonists
Propranalol
Osmolol

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3
Q

What do Class 3 anti-arrhythmics do?

Examples?

A

Block K+ Channels
Sotalol
Amiodarone

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4
Q

What do Class 4 anti-arrhythmics do?

Examples?

A

Block Ca2+ Channels

Verapamil

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5
Q

When do you use Procainamide?

When do you use Quinidine?

A

Acute SVT

Maintain Sinus Rhythm in AF

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6
Q

When do you use Lidocaine?

A

Ventricular Tachycardia

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7
Q

When do you use Propranalol?

A

In Sinus Arrythmias

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8
Q

When do you use Fleconide?

A

WPW
Premature Contractions
SVT

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9
Q

When do you use Amiodarone?

A

AF

Angina

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10
Q

When do you use Sotalol?

A

SVT/VT

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11
Q

When do you use Verapamil?

A

Hypertension
Angina
AF (decrease ventricular rate)
SVT

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12
Q

What are the ADRs of Class Ia?

A

Hypotension
Lupus-like symptoms
Pro-arrythmic

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13
Q

What are the ADRs of Class Ib?

A

Pro-arrhythmic

Dizziness

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14
Q

What are the ADRs of Class Ic?

A

Pro-arrhythmic
Cannot use in damaged tissues
Sedation
Nausea

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15
Q

What are the ADRs of Class II?

A

Hypotension
Bradycardia
Bronchospasm

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16
Q

What are the ADRs of Class III?

Amiodarone?

A

Pulmonary Fibrosis
Thyroid
LDLs
Hepatic Injury

17
Q

What are the ADRs of Class III?

Sotalol?

A

Fatigue
Insomnia
Arrhythmia

18
Q

What are the ADRs of Class IV?

A

AV Conduction problems
Hypotension
Liver Faiure

19
Q

What is the effect of Class Ia?

A

Decrease Phase 0 slope
Decrease Phase 4 slope
Longer QT (refractory period)

20
Q

What is the effect of Class Ib?

A

Decreases phase 3 and AP
No effect on normal tissues
Good on rapidly firing tissues

21
Q

What is the effect of Class Ic?

A

Decreases Phase 0
Lengthens AP and automacity
Whole ECG changes

22
Q

What is the effect of Class II?

A

Slows heart rate and lowers contraction
Lowers phase 4 slope
Decreases AV conduction

23
Q

What is the effect of Class III?

A

Longer AP and Refraction
Increases threshold to lower automacity
Lowers AV conductance

24
Q

What is the effect of Class IV?

A

Decrease Automacity
Decrease AV conductance
Increase refraction and slope of phase 4

25
Q

What are some CI of Lidocaine?

A

Don’t use in AF

26
Q

What are some CI of Verapamil?

A

Don’t use in AV block

PPE (25 decks)

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