100 NSAIDS/Antipyretics Flashcards
acetylsalicylic acid
name/class
name
acety-lsa-licy-lic acid
ASPIRIN
class
platelet aggregation inhibitor, analgesic, anti-inflammatory, antipyretic
acetylsalicylic acid
ASPIRIN
MOA/ind/contra
moa
changes the surface of platelets decreasing the effectiveness of clot-forming. blocks formation of thromboxane A2 so it cant aggregate platelets. last as long as platelet is alive 5-7 days
ind
- Ischemic chest pain
- mild pain
- fever
contra
- risk vs benefit for chest pain
- hypersensitivity to NSAIDS or salicylates
- active gi bleed
- bleeding disorders
acetylsalicylic acid
ASPIRIN
dose
160-325mg non-coated po chewed
acetylsalicylic acid
ASPIRIN
s/s
s/s
- n/v
- gi bleeding/ulcers
- heartburn
- wheezing
- tinnitus
- hepatotoxicity in a large dose
precautions
can cause Rye syndrome in pediatrics (should not be given peds)
can cause bronchoconstriction in asthmatics
acetaminophen
name/class
name
aceta-mino-phen (Mino fin)
TYLENOL
CLASS
antipyretic, nonnarcotic analgesic
acetaminophen
TYLENOL
MOA/IND/CONTRA
MOA
acts on the hypothalamus to produce antipyresis
may block pain impulses and inhibit cyclooxygenase
little anti-inflammatory property
ind
mild-moderate pain
fever
contra
severe liver disease
hypersensitivity
acetaminophen
TYLENOL
dose
325-650 mg Po q4-6hr (AHS 325-975)
acetaminophen
TYLENOL
s/s
s/s
- angioedema
- dizziness
- urticaria
- laryngeal edema
- n/v
- hepatic toxicity in big dose
precaution
- liver problems
- can potentiate warfarin and apixaban
ketorolac
name/class
name
keto-rol-ac (get that keto diet rolling ac)
TORADOL
class
NSAID
ketorolac
TORADOL
moa/ind/contra
moa
NSAID inhibits prostaglandin synthesis, which produces peripheral mediated analgesia
no sedative properties
ind
short term pain management <5days
contra
- allergy to ASA & NSAIDs
- bleeding disorders
- renal failure
- active peptic ulcers
ketorolac
TORADOL
dose
30mg SIVP
30-50 IM
½ for >65y/o
ketorolac
TORADOL
s/s
s/s
- edema
- hypertension
- dizziness
- constipation
- diarrhea
- drowsiness
