10) regulación traduccional: nivel de degradación del ARNM Flashcards

1
Q

miRNA no codificante porqué

A

No codifica para proteínas

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2
Q

Forma a los miRNA

A

RNA pol II

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3
Q

Regulan la expresión de genes

A

miRNA

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4
Q

Remueve caperuza y cola de poli A; hace pre … “forma de pasador”

A

Drosha

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5
Q

Encargado de segundo corte, quita el bucle y deja dos cadenas

A

Dicer

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6
Q

Parte de complejo RISC, endonucleasa que corta ARNm, esto es por la unión completa

A

AGO2

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7
Q

Interrumpe paso de ribosomas debido a su tamaño y a una unión parcial, inhibiendo la traducción

A

Complejo RISC

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8
Q

Checar que me falta

A
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9
Q

Sitio donde se degradan ARNm

A

Cuerpos P

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10
Q

Facts cuerpos P

A
  • Eznimas que retiran el capuchón
  • Exonucleasas
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11
Q

checa que falta

A
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12
Q

Facts de siRNA

A
  • Doble
  • 20-27 pb
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13
Q

Origen de siRNA

A
  • Exógeno: virus
  • Endógeno: transposones
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14
Q

Encargado de cortar dsRNA

A

Dicer-2

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15
Q
A
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