10. Raised ICP Flashcards

1
Q

What are the types of brain hernias?

A

Subfalcine herniation
Tonsillar herniation
Uncal herniation

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2
Q

What are thee clinical features of raised ICP?

A
Headaches
Nausea and vomiting
Visual disturbances
Confusion
Seizures 
Amnesia
Papilloedema
Focal neurological signs
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3
Q

What is Cushing’s triad?

A

3 primary signs that indicate increased ICP

Hypertension, bradycardia, irregular breathing

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4
Q

What can cause too much blood within cerebral vessels?

A

Raised arterial pressure - malignant hypertension

Raised venous pressure - SVC obstruction

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5
Q

What can cause too much blood outside the cerebral vessels?

A

Haemorrhage - extradural, subdural, subarachnoid

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6
Q

What is malignant hypertension?

A

Systolic >180 or diastolic >120

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7
Q

What are the signs of malignant hypertension?

A

Retinal haemorrhages
Encephalopathy
Left ventricular hypertrophy
Reduced renal function

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8
Q

What happens in SVC obstruction?

A

Reduction in venous return from head and neck and upper limbs
Most common cause is malignancy

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9
Q

What will be seen on CT of extradural haematoma?

A

Biconvex shape

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10
Q

What will be seen on CT of subdural haematoma?

A

Concave/crescent shape

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11
Q

What is subarachnoid haemorrhage most commonly caused by?

A

Rupture of intracranial aneurysm (circle of Willis)

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12
Q

What is congenital hydrocephalus?

A

Present at birth

Build up of CSF

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13
Q

How do patients with congenital hydrocephalus present?

A

Enlargement of head circumference
Downward gaze
Delay in neurological development

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14
Q

What can cause obstructive hydrocephalus?

A

Aqueduct stenosis
Neural tube defects
Dandy-Walker syndrome (enlargement of 4th ventricle due to partial blockage of outlets)

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15
Q

What is communicating hydrocephalus?

A

Overproduction got CSF or reduced absorption of CSF (choroid plexus papilloma, infection and inflammation leading to scarring at subarachnoid space)

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16
Q

What are the acquired causes of hydrocephalus?

A

Intraventricular haematoma
Tumour
Infection
Trauma

17
Q

What are the 4 types of cerebral oedema?

A

Vasogenic
Cytotoxic
Osmotic
Interstitial

18
Q

What is vasogenic cerebral oedema?

A

Disruption of BBB

Breakdown of tight junctions = increased permeability

19
Q

What is cytotoxic cerebral oedema?

A

Injury to cels of the brain

Derangement in ATP-dependent transmembrane pumps - intracellular accumulation of fluid

20
Q

What is osmotic cerebral oedema?

A

Usually osmolarity of extracellular fluids is equal on both sides of BBB

21
Q

What is interstitial cerebral oedema?

A

Increased pressure within ventricles, eventual damage to their linings
CSF can now be found in brain parenchyma

22
Q

What investigations are done in raised ICP?

A

Vital signs, ECG, fundoscopy
FBC, U and Es, CRP, clotting, blood culture
CT scan, MRI

23
Q

What is the management for raised ICP?

A

Primary survey and stabilise patient
Elevate head of bed, avoid pyrexia, analgesia
Anticonvulsants, sedation or neuromuscular blockade, mannitol or hypertonic saline
Ventriculostomy, decompressive craniectomy