10: Puberty, Menstrual Disorders Flashcards
Ovarian cycle - follicular phase
Onset of menstruation to LH surge
Ovarian cycle - luteal phase
LH surge to 1st day menses
At what point in the menstrual cycle does estrogen peak?
Just prior to LH surge
At what point in the menstrual cycle does progesterone peak?
5-7 days after ovulation
Corpus luteum
Formed after ovulation and secretes progesterone
Corpus albicans
Avascular scar that replaces corpus luteum in absence of pregnancy
Menstrual phase
RBC extravasation, sloughing of functionalis layer and compression of basalis layer
Proliferative phase
Endometrial growth, estrogenic stimulation, increase in arteries, increase in mitoses
Secretory phase
Following ovulation, progesterone secretion increases, glands are tortuous, mucus and glycogen secreted, endometrial lining at maximum thickness
Median age of menarche
12.43 years
Primary amenorrhea
No menstruation by 13 y/o without secondary sexual development OR by 15 years with secondary sexual characteristics
When is menses likely associated with anemia?
Greater than 80cc blood loss/changing pad q1-2 hours
Stages of normal pubertal development
TAG-ME: Thelarche, Adrenarche, Growth, MEnarche
Thelarche
Breast development; 1st sign puberty, requires estrogen
Adrenarche
Development of pubic/axillary hair; requires androgens
Maximal growth
Occurs ~1 year before onset menses
Menarche
Onset of menses
Tanner stage 1
Breast: Preadolescent, elevation of papilla only
Hair: Preadolescent, absence of pubic hair