10. Dosimetry Flashcards
What is ionizing radiation?
radiation with high enough energy to produce ion pairs directly or indirectly (+ ion, - free electron) while absorbed in the matter.
It includes corpuscular radiations and high-energy electromagnetic radiations (X-rays and γ-rays).
2 types of ionizing radiations
(1) Direct ionization (in case of charged particles)
2) Indirect ionization (in case of uncharged particles and high-energy electromagnetic radiation
2 Examples of direct ionization
Alpha
Beta
2 example of indirect ionization
Gamma
X-rays
The part of the ionizing radiation that is absorbed in a living organism leads, via different processes (physical, radiochemical, molecular biological), to macroscopic biological changes or damage, the severity of which depends on the parameters listed below:
List 4 parameters
(1) Type of radiation
(2) sensitivity of the organ or part of the body that received the radiation
(3) the received dose (D)
(4) the time course of the received dose
What is direct effect?
It occurs when the ionizing radiation is absorbed in biologically important macromolecules (e.g., DNA), and causes damage there directly.
What is indirect effect?
It occurs when the ionizing radiation is absorbed in water, the largest constituent, by quantity, of the organism, and induces the formation of free radicals (∙H, ∙OH, etc.).
=> These highly reactive free radicals then interact with the biologically important macromolecules.
What is deterministic effect?
the probability of radiation damage increases abruptly above the threshold dose.
Above this dose level, the severity of the damage is proportional to the dose.
Erythema and cataract (transparency loss of the eye lens) are typical deterministic effects.
What is stochastic effect?
the probability of radiation damage is proportional to the dose (a threshold dose cannot be defined).
Genetic disorders and some forms of cancer (which are a consequence of mutations) are caused by this “random” effect.
What is the role of radiation protection?
To prevent the deterministic effects
To decrease the risk of the stochastic effects to an acceptable level in the proximity of the radiation sources (therapeutic and diagnostic X-ray devices, closed and open radioactive preparations).
What is absorbed dose?
the amount of energy absorbed per unit mass
∆E - energy absorbed by mass ∆m
Unit - 1Gy = 1 J/kg
Formula for exposure
Where ∆q is the positive charged produced in air of mass ∆m by ionization
Unit - C/kg
2 types of rays that EXPOSURE formula is valid for
X-rays
Gamma rays
The role of effective dose equivalent (E)
It expresses the biological damage of the individual tissue or organ
formula for effective dose
the equivalent dose, which is multiplied by a tissue weighting factor (wT) characteristic for the tissue sensitivity towards radiation damage
Unit- sievert