10 Flashcards

1
Q

define severe depression

A
3/3 of:
- persistent low mood >2weeks
- fatigue 
- anhedonia 
8+ of:
- self harm/ suicidal thoughts/ ideation
- guilt
- decreased appetite
- disturbed sleep
- reduced concentration 
- low self-esteem 
- bleak and pessimistic views of the future
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2
Q

how long does a short term detention certificate last for

A

28 days

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3
Q

valproic acid side effects

A
  • thrombocytopenia
  • N+V
  • weight gain
  • sedation
  • tremor
  • hair loss
  • increased risk of neural tube defect
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4
Q

presentation high dose alcohol

A
  • disorientation
  • N+V
  • slurred speech
  • impaired attention and judgement
  • unsteadiness
  • flushing
  • stupor
  • nystagmus
  • mood instability
  • disinhibition
  • unconscious
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5
Q

carbamazepine target level

A

4-12

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6
Q

investigations/ checks pre-starting carbamazepine

A
  • baseline LFTs
  • FBC
  • ECG
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7
Q

delusional perceptions

A

see something that is real but instantly believes there is a meaning behind it

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8
Q

first and second line ADHD management

A

methylphenidate

atomoxetine

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9
Q

downsides to cocaine

A
  • damage to nose and airway
  • convulsions with resp failure
  • cardiac arrythmias
  • MI
  • hypertension
  • toxic confusion
  • paranoid psychosis
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10
Q

effects MDMA

A
  • euphoria followed by feeling of calm
  • increase in sociability
  • inability to distinguish between what is and what isn’t desirable
  • lasts 20mins-4hours
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11
Q

describe how reward centres work

A

ventral tegmental area (VTA) neurons are stimulated, dopamine is released causing a sensation of pleasure/ reward

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12
Q

conditions which may involve psychosis

A
  • depression
  • schizophrenia
  • bipolar
  • delirium
  • severe affective disorder
  • depressive episode with psychotic symptoms
  • manic episode with psychotic symptoms
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13
Q

what is the psychoactive agent in cannabis

A

tetrahydrocannabinol

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14
Q

retardation

A

severe psychomotor impairment, slowing of motor responses including speech

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15
Q

depression

A

unpleasant emotion in which sadness predominates

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16
Q

describe dispositional tolerance

A

less drug reaches active site
e.g. decreased rate of absorption
increased secretion

17
Q

describe alcoholic hallucinations

A

develops 12-24 hours after heavy drinking stops suddenly
auditory or visual
most commonly accusatory or threatening voices

18
Q

define alcoholic dependance

A

for >1 month, 3 or more of:

  • cravings
  • difficulty controlling use
  • increased tolerance
  • physiological withdrawal on reduction
  • persistence despite harmful consequences
19
Q

physiological changes acute alcoholic hepatitis

A
  • bilirubin >125
  • INR >1.5
  • WCC >15
  • age >50
  • urea >5
20
Q

cause of acute alcoholic hepatitis

A

> 8 units of alcohol per day

21
Q

affect of alcoholism on relationships

A
  • aggression
  • marital difficulties
  • poor parenting
  • neglect
  • loss of friendship/ social support
22
Q

effect of alcohol on physical health

A
  • immunosuppression
  • liver problems e.g. cirrhosis
  • endocarditis
  • acid reflux
  • teeth damage
  • decrease muscle
  • memory loss
  • dementia
  • hallucinations
  • fits
  • arrythmias
  • ischaemic and haemorrhagic stroke
  • HF
  • hypertension
  • pancreatitis