#1 Owen - Acid-Base Regulation Flashcards
Lab reports come back and you discover your patient has metabolic acidosis with an increased anion gap and normal Cl-. What are the likely causes?
In my increased ANGer (increased ANion Gap) I SLAM'D the table. Starvation Lactic acidosis Aspirin poisoning Methanol Diabetes mellitus
A different patient’s lab reports come back and the anion gap is normal but the Cl- levels are increased. What are the likely causes?
Increasingly hyper Clara (hyperchloremia) Nagged (Normal Anion Gap) me to play CARDs. Carbonic anhydrase inhibitors Addison disease Renal tubular acidosis Diarrhea
Lab reports are back and your patient has the following values: arterial pH = 7.35 Plasma HCO3- = 14 Plasma PCO2 = 26 Plasma Cl- = 102 Plasma Na+ = 140 What type of acid-base disorder does this patient have? What is the anion gap?
Metabolic Acidosis w/respiratory compensation
Anion gap = 140-102-14 = 24
Normal anion gap (8-16 Eq/L)
Normal Cl- (98-106)
Your patient’s labs came back with a pH of 7.1 and a CO2 of 50.You are contemplating the cause of your patient’s respiratory acidosis. What are you thinking about?
With respiratory acidosis the Brain will get LUPE. Brain LUng disorders Pneumonia Emphysema (smoking history)
Labs are returned for Aldo. His pH is 7.5 and his HCO3 is 27. What are the possible causes of his metabolic alkalosis?
ALDO (Aldosterone) was eating a MEAL (MEtabolic ALkolsis) and was consuming large amounts of BASE. He was VOMITING DIURETICS.
-Increased base intake
- Vomiting gastric acid
- Mineralcorticoid excess (Aldosterone)
- Overuse of diuretics (except carbonic anhydrase inhibitors)
[Carbonic anhydrase inhibitors cause increased excretion of HCO3]
Aldosterone causes increased secretion of what cation into the tubules?
K+
Overuse of diuretics causes depletion of what cation?
K+
Depletion of K+ leads to increased tubular secretion of ?
H+
Increased tubular secretion of H+ leads to reabsorption and new production of what buffer?
HCO3
