1: HISTORY OF MEDICAL TECHNOLOGY PROFESSION Flashcards
• “Father of Medicine”
• author of Hippocratic Oath
• advocated the examination of urine to diagnose disease
HIPPOCRATES (300 BC)
• created a system of pathology through measure of body fluids (four humors e.g. blood, phlegm, yellow bile, black bile) with the Pythagorean theory
• founder of experimental physiology
GALEN (180 AD)
• first description of “hematuria” attributed to the failure of kidneys to function properly in filtering the blood
RUFUS OF EPHESUS (50 AD)
• devised guidelines for the use of urine as a diagnostic aid
ISAAC JUDAEUS (900 AD)
• discovered the circulation of blood
• marked the beginning of a period of mechanical explanations for a variety of functions and processes
WILLIAM HARVEY (1578-1657)
• earliest microscopist
• probably the first to use the microscope to investigate the causes of disease
ATHANASIUS KIRCHER (1602–1680)
• used the microscope to document the existence of cells
ROBERT HOOKE (1635–1703)
• founder of Histology
o studies the microscopic anatomy of biological tissues
• famous for his investigations on:
o embryology and the histology
o physiology of the glands
o viscera
MARCELLO MALPIGHI (1628–1694)
• observed that urine containing protein would form a precipitate when boiled with acetic acid.
FREDERIK DEKKERS (1694)
• first to notice the characteristic sweet taste of diabetic urine
• established the principle for the differential diagnosis of “diabetes mellitus” and “diabetes insipidus”
THOMAS WILLIS (1621–1675)
• first to perform direct transfusion of blood from one animal to another
RICHARD LOWER (1631–1691)
• discovered the cause of coagulation, which he called “coagulable lymph,” also known as fibrinogen
WILLIAM HEWSON (1739–1774)
• works include:
o descriptions of the germinal vesicle in the embryo
o description and naming of protoplasm
o discovery of the sudoriferous glands of the skin and their excretory ducts
o numerous descriptions of brain, nerve, and muscle cells
JOHANNES EVANGELISTA PURKINJE (1823)
• introduced the concepts of aerobic and anaerobic bacteria
• discovered partial heat sterilization or Pasteurization
• attenuated vaccines
LOUIS PASTEUR (1822–1895)
• discovered the complete life history and sporulation of the anthrax bacillus
• developed a method of obtaining pure cultures of organisms
• played a role in perfecting the method of steam sterilization
• discovered the tubercle bacillus by other special culture and staining methods and formulated a rule for determining the specificity of disease-causing organisms
• discovered Vibrio cholera and recognized its routes of transmission
ROBERT KOCH (1843–1910)
• established ward laboratories at Johns Hopkins Hospital, where routine tests were carried out by attending physicians.
SIR WILLIAM OSLER (1898)
• discovered methods of antisepsis using carbolic acid.
JOSEPH LISTER (1827–1912)
• first to observe the role of calcium salts in the coagulation of blood
• devised a coagulometer to estimate coagulation time
SIR ALMROTH EDWARD WRIGHT
• developed many methods of drying and fixing blood smears using heat
• discovered mast cells and saw their granulations using a basic aniline stain
• classified white blood cells into different morphological types
• discovered methylene blue as a bacterial stain
PAUL EHRLICH (1854–1915)
• accidentally discovered penicillin
SIR ALEXANDER FLEMING (1881–1955)