1 Cranial Nerves Flashcards
General difference between CN and SN
Cranial nerves contain inflow/outflow of brain
Spinal nerves contain inflow/outflow of spinal cord
Classification of CN based on what?
Embryological, structural/anatomical, and functional characteristics
Neurons carrying similar modalities are called ___ and arise from ___.
functional components; functional columns
what can be sensory, motor, or both (mixed)?
cranial NERVES
what can be sensory or motor but never both?
cranial nerve NUCLEI
is there a one-to-one correlation between cranial nerves and functional columns?
can a particular cranial nerve carry several distinct functional modailities?
NO, YES
the alar plate gives rise to ___ nuclei from the ___ horn
sensory; dorsal
the basal plate gives rise to ___ nuclei from the ___ horn
motor; ventral
differences between CN nuclei vs. dorsal and ventral horns
- lateromedial vs. dorsoventral (anterior/posterior) column organization
- neuronal migration is more extensive in brain stem
- discontinuous columns
how does the brainstem develop?
starts posteriorly at dorsal sensory or alar plate
opens up laterally like a book
Motor nuclei are [continuous/discontinuous] and sensory nuclei are [continuous/discontinuous].
discontinuous; continuous
where are the motor nuclei columns located in relation to sulcus limitans?
medial
where are the sensory nuclei columns located in relation to sulcus limitans?
lateral
1st letter: G
General
types of neurons found BOTH in spinal nerves and cranial nerves
1st letter: S
Special
types of neurons ONLY FOUND in cranial nerves NOT spinal nerves
2nd letter: S
Somatic
types of neurons innervating structures derived from somites (skin, skeletal m., cartilage etc.)
2nd letter: V
Visceral
types of neuron innervating:
- viscera: cardiac ms, smooth ms, and glands
- structures derived from or associated with pharyngeal arches
3rd letter: E
Efferent
MOTOR neurons to skeletal, cardiac, and smooth muscle; also secretomotor neurons to glands
3rd letter: A
Afferent
SENSORY neurons
what classifications can be used for spinal nerves
GSA, GVA (pain), GVE, GSE
what classifications can be used for cranial nerves?
GSA, GVA (reflex), GVE, GSE
SSA, SVA, SVE
what carries pain, temp, and mechanical info from receptors in skin, muscles and joints
General Somatic Afferent (GSA)
what carries sensory info from receptors in visceral structures (pain/reflex)
General Visceral Afferent (GVA)
what contains preganglionic autonomic fibers
General Visceral Efferent (GVE)
(typically the para/sympathetics)
what innervates skeletal muscle (alpha and gamma motor neurons)
General Somatic Efferent (GSE)
(something you control)
what supplies special senses of vision, auditory sensation and vestibular (balance equilibrium) apparatus?
Special Somatic Afferent (SSA)
what supplies chemical senses of taste and smell?
Special Visceral Afferent (SVA)
what innervates striated ms derived from pharyngeal arches?
Special Visceral Efferent (SVE)
CN in telencephalon
CN I - olfactory
olfactory receptor neuron is derived from ___
nasal placode
olfactory bulb is derived from ___
telencephalon
what type of neurons are the olfactory receptor
bipolar neurons
where are olfactory receptors found
within olfactory epithelium lining the superior nasal chonca
axon bundles from the olfactory nerve penetrate the ___ and synapse with ___ in the ___.
cribiform plate; mitral and tuft cells; olfactory bulb
CN in diencephalon
CN II - optic
what is CN II derived from?
Optic vesicle (outpouching of diencephalon)
CN in midbrain
CN III - oculomotor
CN IV - trochlear
where does CN III emerge from
interpeduncular fossa - space between cerebral peduncles
where does CN IV emerge from
from midbrain, directly inferior to inferior colliculus
marks PONS-MIDBRAIN JUNCTION
CN in pons
V - trigeminal
VI - avducens
VII - facial
VIII - vestibulocochlear
what CN exits laterally at mid-pons
trigeminal nerve V
where do CN VI, VII, and VIII exit the pons?
exit at pontomedullary junction in a medial-lateral sequence
CN in medulla
IX - glossopharyngeal
X - vagus
XII - hypoglossal
what emerges along postolivary sulcus rostrally?
CN IX - glossopharyngeal
what emerges as rootlets along postolivary sulcus caudally?
CN X - vagus
rootles of ___ exit along preolivary sulcus between pyramids and olive
CN XII - hypoglossal
CN in spinal cord
CN XI - spinal accessory
where does CN XI arise from
ventral horn in cervical spinal cord (C1-C5)
what column does skeletal somatic motor
medial motor column
what column does autonomic/preganglionic parasympathetics
intermediate motor column
what column does the branchiomeric/pharyngeal arches
lateral motor column
what CN are associated with Medial Motor Column GSE
Occulomotor III - midbrain
Trochlear IV - midbrain
Abducens VI - pons
Hypoglossal XII - medulla
Spinal Accessory XI - C1-C5
what CN are associated with Intermediate Motor Column GVE
Edinger-Westphal III - midbrain
Superior Salvatory nucleus VII - pons
Inferior Salvatory nucleus IX - medulla
Dorsal motor nucleus X - medulla
what ganglion does Edinger-Westphal go to?
(III) ciliary ganglion
what ganglia does superior salvatory nucleus go to
pterygopalatine ganglion or submandibular and sublingual ganglion
what ganglion does inferior salvatory nucleus go to
otic ganglion
what ganglion does dorsal motor nucleus go to
terminal (intramural) ganglia
what CN associated with lateral motor column (SVE)
motor nucleus of CN V (PA1) - pons
motor nucleus of CN VII (PA2) - pons
nucleus ambiguous [CN IX (3) and CN X (PA 4 and 6)]- medulla
what column does visceral afferent and taste (solitary nucleus)
medial sensory column
what column does hearing and balance (vestibulochcoclear nucleus)
intermediate (posterolateral) sensory column
what column does somatic afferent (trigeminal nuclei)
lateral sensory column
what main nuclei and nerve are part of the medial sensory column
- solitary nucleus (SVA and GVA): pons-medulla
- olfactory nerve CN I (SVA)
what are the nuclei classifications part of the solitary nucleus? what are the CN composed of?
- gustatory nucleus (SVA) - VII, IX, and X
- cardiorespiratory nuccleus (GVA) - VII, IX, and X
what is the rostral part of the solitary nucleus? the caudal part?
rostral: gustatory nucleus (SVA)
caudal: cardiorespiratory nucleus (GVA)
is CN I associated with brainstem columns
NO
what nuclei are associated with intermediate sensory column (SSA)
- vestibular nucleus (SSA)
- cochlear nucleus (SSA)
- Optic nerve (CN II) (SSA) - NOT associated with brainstem columns
what is somatosensory to the head, oral cavity, and external ear?
lateral sensory column (GSA)
what is the rostral continuation of the dorsal horn and extends from caudal medulla to rostral midbrain?
lateral sensory column (GSA)
what are the nuclei of the lateral sensory column (GSA)? CN associated with it?
- main (chief) or principal sensory nuclei - VII, IX, X
- spinal trigeminal nuclei - VII, IX, X
- mesencephalic nuclei
CN associated and function of:
GSA
V, VII, IX, X - general sensation and proprioception
CN associated and function of:
GSE
III, IV, VI, XI - motor to extraocular m.
XII - motor to tongue
CN associated and function of:
GVA
VII, IX, X - general sensation from viscera
CN associated and function of:
GVE
III, VII, IX, X - PS to viscera
CN associated and function of:
SSA
II - ss input from retina
VIII - ss input from vestibulocochlear apparatus
CN associated and function of:
SVA
I - smell
VII, IX, X - taste
CN associated and function of:
SVE
V, VII, IX, X - motor to branchiomeric m.
Name and nerve type:
CN I
Olfactory - SVA
Name and nerve type:
CN II
Optic - SSA
Name and nerve type:
CN III
Oculomotor - GSE, GVE
Name and nerve type:
CN IV
Trochlearr - GSE
Name and nerve type:
CN V
Trigeminal - SVE and GSA
Name and nerve type:
CN VI
Abducens - GSE
Name and nerve type:
CN VII
Facial - SVE, GVE, SVA, GSA, GVA
ALL EXCEPT SSA
Name and nerve type:
CN VIII
Vestibulocochlear - SSA
Name and nerve type:
CN IX
Glossopharyngeal - SVE, GVE, GVA, SVA, GSA
ALL EXCEPT SSA
Name and nerve type:
CN X
Vagus - SVE, GVE, GVA, SVA, GSA
ALL EXCEPT SSA
Name and nerve type:
CN XI
Spinal Accessory - GSE
Name and nerve type:
CN XII
Hypoglossal - GSE
sensory ganglia for CN I
specialized cells in olfactory epithelium
sensory ganglia for CN II
specialized cells in retina
sensory ganglia for CN V
trigeminal gangliion
sensory ganglia for CN VII
geniculate ganglion
sensory ganglia for VIII
specialized cells in cochlea
sensory ganglia for IX
superior and inferior glossopharyngeal gangliia
sensory ganglia for CN X
superior and inferior jugular ganglia