1: Concepts and cells Flashcards
2 types of immunity
- innate
- adaptive
2 types of innate immunity
- humoral
- cellular
types of innate humoral immunity (3)
- complement
- cytokines/chemokines
- antimicrobial peptides
types of innate cellular immunity (3+)
- monocytes (macrophages, dendritic cells)
- natural killer cells
- granulocytes (mast cells, eosinophils, basophils, neutrophils)
adaptive humoral immunity
antibodies
types of adaptive cellular immunity (2+)
- b cells
- t cells (helper, cytotoxic, regulatory)
3 components of the immune system
- soluble components
- cellular components
- tissues
importance of soluble components of the immune system (3)
- released by immune cells, fibroblasts, etc
- affect differentiation and activities of immune cells
- can have direct action on invading pathogens/tumors
importance of cellular components of immune system (2)
- innate responses
- adaptive responses
importance of tissues of the immune system
- primary organs
- secondary organs
where do all cells of the immune system arise from
bone marrow precursors
what drives differentiation of immune cells down the pathway
cytokines
2 types of progenitor cells
- lymphoid
- myeloid
what do lymphoid progenitors become (3) and where
- b cells, t cells, nk cells
- bone marrow then lymph nodes
what do myeloid progenitors become (3) and where
- granulocytes, platelets, erythrocytes
- bone marrow, blood, tissues