1: Combined Contraceptive Hormone Generations Flashcards
What generation? Progestin norethynodrel
1st
What generation? Progestin norethindrone
1st
What generation? Progestin norethindrone acetate
1st
What generation? Progestin ethynodiol diacetate
1st
What generation?
- Well tolerated
- Found in many generic formulations and some low-dose brand-name COCs
- Unscheduled bleeding/spotting at lower doses
1st
What generation? Progestin norgestrel
2nd
What generation? Progestin levonorgestrel
2nd
What generation?
- Potent with long half-life
- Increase in androgen-related side effects (adverse effects on lipids, oily skin, acne, facial hair)
2nd
What generation? Progestin desogestrel
3rd
What generation? Progestin norgestimate)
3rd
What generation?
- Reduced androgenic SEs
- Fuller impact of estrogen which may increase risk of thromboembolism
3rd
What generation?
- Antimineralcorticoid and antiandrogenic properties
- Tx of PMDD and acne
- No increased risk of thromboembolism
4th
What generation? Progestin drospirenone
4th
What generation?
More profound, diverse, and discreet endometrial effect compared to others (progestin).
Next Generation
What generation of estrogen?
- Availability: 20, 25, 30, 35, 50 mcg and one preparation containing 10mcg
Next Generation
What generation? Progestin dienogestrel
Next Generation
What generation? Estrogen ethinyl estradiol (EE)
Next Generation
Name the 1st generation progestins (4).
- Norethynodrel
- Norethindrone
- Norethindrone acetate
- Ethynodiol diacetate
Name the 2nd generation progestins (2).
- Norgestrel
- Levonorgestrel
Name the 3rd generation progestins (2).
- Desogestrel
- Norgestimate
Name the 4th generation progestin (1).
Drospirenone
Name the next generation hormones (2).
- Progestin: dienogestrel
- Estrogen: ethinyl estradiol
Which generation would you avoid for someone with acne or facial hair growth?
2nd generation
Which generation has more spotting and unscheduled bleeding at lower doses?
1st generation
Which generation has a lesser androgenic effects, but more estrogenic effects leading to a possible increased risk for venous thromboembolism?
3rd generation
Which generation is best for treatment of acne and PMDD?
4th generation
Which generation has more profound, discreet, and diverse endometrial effects compared to other progestins?
Next generation