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System P 2 > 1 > Flashcards

1 Flashcards

1
Q

What skin disease is desired as a red macular, with a pale eroded center, with possible vesicles or bullae?

A

Erythema multiforme

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2
Q

What is the sign associated with seborrheic keratosis?

A

Lester-trelat sign (paraneoplastic syndrome)

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3
Q

What condition is assocaited with epidermal hyperplasia and dermal scaring?

A

Lichen simplex chronicus

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4
Q

What is the most common form of eczema ?

A

Allergic contact dermatitis

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5
Q

Does lichen planus self resolve?

A

Yes in about 1-2 years

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6
Q

Seborrheic dermatitis is also know as what?

A

Cradle cap

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7
Q

Dactylitis (sausage digits) is assocaited with what?

A

Psoriasis patients (35%)

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8
Q

High grade HPV infections are caused by what?

A

HPV-16 AND HPV 18

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9
Q

What condition begins as as fever and malaise, 24-48 hours. Macules and vesicles, most common in daycares?

A

Hand foot and mouth disease

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10
Q

What is a dysplastic lesion in areas of sun exposure with a “sand paper like” texture ?

A

Actinic keratosis

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11
Q

What is a condition of cumulative UV damage with purple macules?

A

Senline purpura

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12
Q

What is a sign associated with lichen planus>?

A

Wickhams striae (70% have oral involvement )

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13
Q

What what is urticaria?

A

Hives

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14
Q

What makes up chronic inflammatory dermatoses ?

A

Psoriasis, lichen planus, lichen simplex chronicus

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15
Q

Senile purpura effects ____%of every >than___years old?

A

25%, 90 years old

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16
Q

Dermatitis herpetiformis most commonly effects who?

A

20-40 year old males

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17
Q

IgE dependent = ?

A

Feature of common allergens

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18
Q

What are functions of the skin?

A

Barrier, prevents water loss, UV protection

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19
Q

What is a common Nevus?

A

Benign growth, in the dermis, well defined borders, sometimes called a beauty mark

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20
Q

What condition is raised itchy and scaly and caused by repetitive traum such as OCD, anxiety, depression ?

A

Lichen simplex chronicus

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21
Q

Most genital warts comes form what forms of HPV?

A

6, 11

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22
Q

What is the 3rd most common skin cancer?

A

Melanoma

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23
Q

Psoriatic Arthritis is also called wha?

A

Pencil in cup deformity

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24
Q

What is more common? Pemphigus vulgaris or pemphigus foliaceus?

A

Pemphigus vulgaris

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25
Q

What kind of boarder does melanoma have?

A

Notched

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26
Q

What are risks for lichen planus?

A

ARD, dry eyes, arsenic, HCV infxn

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27
Q

What is a dysplastic nevus?

A

Larger, various colors, irregular borders

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28
Q

What kind of lesion is associated with erythema multiform ?

A

Targetoid

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29
Q

What are the risks for acanthosis nigricans?

A

Diabetes, obesity and genetics

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30
Q

What condition is associated with a fishnet like pattern of IgG?

A

Pemphigus

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31
Q

What organism causes most (80%) of all impetigo infections?

A

Staph. Aureus

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32
Q

What does chronic eczema look like?

A

Scaling plaque

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33
Q

What is more common verruca vulgaris or verruca plana ?

A

Verruca vulgaris

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34
Q

What skin condition may disguise cancer, and the onset is after 40 ?

A

Solar lentigo

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35
Q

What condition is associated with a red rash with “honey colored crust”

A

Impetigo

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36
Q

Who does impetigo most commonly affect?

A

Children and adolescent athletes

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37
Q

What is an autoimmune skin condition that has T cells at the dermoepidermal junction?

A

Lichen Planus

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38
Q

Is seborrheic keratosis benign or malignant ?

A

Benign

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39
Q

Psoriatic arthritis occurs in what percent range or psoriasis patients?

A

5-30

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40
Q

Pemphigus affects what group of patients?

A

Middle aged or elderly females

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41
Q

Low grade HPV infections are caused by what?

A

HPV-6, HPV-11

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42
Q

Acute eczematous dermatitis is also know as what?

A

Eczema

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43
Q

What skin disease is desired as a red macular, with a pale eroded center, with possible vesicles or bullae?

A

Erythema multiforme

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44
Q

What is more severe acne vulgaris or cystic acne ?

A

Cystic

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45
Q

Are fungal infections itchy?

A

Yes INTENSLY ITCHY (pruritus)

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46
Q

What organism causes aspergillosis?

A

Aspergillus fumigatus

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47
Q

A familial dysplastic nevus has what kind of cancer risk?

A

Higher (melanoma)

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48
Q

Where does erythema multiform attack?

A

Junction of the epidermis and dermis

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49
Q

What gene/pathway is associated with basal cell carcinoma ?

A

PTCH (hedgehog pathway) and TP53

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50
Q

What type hypersensitivity is erythema multiform?

A

Type IV

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51
Q

What kind of sensitization is eczema ?

A

CD4+ T cells

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52
Q

What type of invention is warts (verrucae)

A

Viral

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53
Q

Pemphigus vulgaris is located where?

A

Skin and MUCOSA

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54
Q

What organism causes dermal abscesses?

A

Pseudomonas aeruginosa

55
Q

What skin cancer effects adults and the elderly?

A

Melanoma

56
Q

What are the causes of a dermal abscess?

A

Puncture wound or burn injury

57
Q

Is a sebaceous adenoma benign or malignant ?

A

Benign

58
Q

Which form of pemphigus is limited to skin?

A

Pemphigus foliaceus

59
Q

Detachment of the nail (oncholysis) is found in who?

A

1/3 of psoriasis patients

60
Q

What is the most common skin cancer ?

A

Basal cell carcinoma

61
Q

Is dermatoheliosis caused by synthetic or natural exposure?

A

Both

62
Q

What is more severe? Pemphigus vulgaris or pemphigus foliaceus?

A

Pemphigus vulgaris

63
Q

What condition is described as having dark “coin like” lesions with a flat “stuck on” appearance ?

A

Seborrheic keratosis

64
Q

Where does aspergilliosis typically begin?

A

Lungs, quickly spreads to the blood

65
Q

What are symptoms of acne vulgaris?

A

Erythema, pustules, comedones with possible pain.

66
Q

What is an example of a bacterial skin infection?

A

Impetigo and dermal abscesses

67
Q

What skin disease is described as a red macular, with a pale eroded center, with possible vesicles or bullae?

A

Erythema multiforme

68
Q

What type hypersensitivity is erythema multiform?

A

Type IV

69
Q

Where is senile purpura most commonly seen?

A

Extensor surfaces

70
Q

What two syndromes are associated with erythema multiforme major ?

A

Stevens-johnson syndrome, toxic epidermal necrolysis

71
Q

A blockage/inflammation of pilosebaceous region is what?

A

Acne vulgaris

72
Q

What type of erythema multiforme is drug related, and is more aggressive causing a sloughing of epidermis, fluid loss and infection?

A

Erythema multiforme Major

73
Q

Hereditary angioedema is associated with that?

A

Urticaria

74
Q

Where are common places for fungal infections?

A

Skin, NAIL BED

75
Q

What is are another name for genital warts?

A

Condylomata acuminata

76
Q

Are fungal infections superficial or deep? `

A

Superficial

77
Q

What are 3 blistering (bullous) disorders

A

Pemphigus, bullous pemphigoid, dermatitis herpetiformis

78
Q

What fungal infection is an immunodeficiency, highly angioinvasive.

A

Aspergillosis

79
Q

What is a mild form of dermatitis that has patches of red skin, that are scaly, flaky, and itchy. ?

A

Seborrheic dermatitis

80
Q

Xeroderma pingmentosa is assoscited with what?

A

Squamous cell carcinoma

81
Q

Melanoma grows _____early, and _________late.

A

Radial, verticlql

82
Q

Is impetigo contagious ?

A

Yes, very

83
Q

Where does erythema multiform attack?

A

Junction of the epidermis and dermis

84
Q

A firboepithelia polyp is known as what?

A

A skin tag (acrochordon)

85
Q

Where are common locations of acanthosis nigricans?

A

In body folds ( axillae, groin, neck)

86
Q

Where are common places for psoriasis ?

A

Elbow, knees, scalp, glans penis, intergluteal cleft.

87
Q

Is erythema multi form rare

A

Yes

88
Q

What is the atopic triad?

A

Dermatitis, asthma, rhinitis

89
Q

What are treatments for psoriasis?

A

Methotrexate, cyclosporine, phototherapy (UBV)

90
Q

Are warts self limiting?

A

Yes

91
Q

Does most urticaria remain for a long time?

A

No, usually they develop and fade in a few hours

92
Q

What kind of lesion is associated with erythema multiform ?

A

Targetoid

93
Q

Urticaria is what type hypersensitivity ?

A

Type 1

94
Q

Pemphius is what kind of hypersensitivity ?

A

type II

95
Q

What condition affects patients with celiac disease?

A

Dermatitis herpetiformis

96
Q

Bullous pemphigoid have what kind of pattern of IgG?

A

Linear

97
Q

Urticaria effects people or what age and are they itchy?

A

20-40, yes.

98
Q

Wheals (hives, or welts), round, red, swollen rash is associated with what?

A

Urticaria

99
Q

What percent of squamous cell carcinomas metastasize to the lymph nodes

A

5%

100
Q

Is impetigo painful??

A

No

101
Q

What condition is a hyperplasia of melanocytes, that are small brown macules?

A

Solar lentigo

102
Q

What does acute eczema look like?

A

Red, vesicles, oozing, crusts

103
Q

Is a dermal abscesses a shallow or deep infection?

A

Deep

104
Q

What kind of lesion is associated with erythema multiform ?

A

Targetoid

105
Q

What is the second most common skin cancer?

A

Squamous cell carcinoma

106
Q

Auspitz sign is assocaited with what?

A

Psoriasis

107
Q

A sporadic dysplastic nevus has what kind of cancer risk?

A

Low

108
Q

IgE independent = ?

A

ADR to opiates or antibiotics

109
Q

Blisters in pemphigus foliaceus are________?

A

Subcorneal

110
Q

Acne is most common in who during adolescence? Adults?

A

Males. Adults-females

111
Q

What is the mutation that causes seborrheic keratosis?

A

FGFR3 mutation

112
Q

What type of erythema multiform is post infection ( HSV, Fungi) and is a more mild version?

A

Erythema multiforme MINOR

113
Q

Melanomas has what kind of appearance ?

A

STRIKING VARIATION

114
Q

What kind of hypersensitivity is eczema ?

A

Type 1 and type IV

115
Q

What is a flesh toned lesion coated on the head or neck that is slow growing and is more a a consmetic problem than anything?

A

Sebaceous adenoma

116
Q

What are the 6ps got lichen planus ?

A

Pruritic, purple, polygonal, planar, papules, plaque

117
Q

A well demarcated lesion, that is pink to salmon colored covered by a flaky silver-white score is associated with what?

A

Psoriasis

118
Q

What kind of eczema is from a genetic risk, that is a childhood onset and imprecise with age?

A

Atopic dermatitis

119
Q

What is an autoimmune condition, of unknown antigens, t cells in the epidermis, affects 2% of the population and is itchy and life long?

A

Psoriasis

120
Q

Telangiectasia and pyramidine diners are assocaited with what?

A

Dermatoheliosis

121
Q

Melanoma is much more likely is someone has how may dysplastic nevi?

A

> or equal to 10

122
Q

What condition is asymptotically hyper-pigmentation of the skin that has a dark “velvety” appearance?

A

Acanthosis nigricans

123
Q

Dermatoheliosis is the result of what?

A

Uva and uvb exposure

124
Q

What type hypersensitivity is erythema multiform?

A

Type IV

125
Q

What are some different names for fungal infections?

A

My oasis, dermathophytosis, tinea “ring worm “

126
Q

Acne vulgaris affects what percent of the population? Severe?

A

80%, severe 20%

127
Q

Which skin condition do some consider squamous cell carcinoma in situ?

A

Actinic keratosis

128
Q

Hand foot and mouth disease is an infection with what?

A

Coxsackievirus

129
Q

Blisters of bullous pemphigoid are________?

A

Subepidermal

130
Q

In pemphigus vulgaris blisters are________?

A

Suprabasil

131
Q

What is a syndrome associated with acanthosis nigricans?

A

Paraneoplastic syndrome

132
Q

What kind of acne is large, filled with edema, pus, and more likely to produce scaring?

A

Cystic acne

133
Q

Where does erythema multiform attack?

A

Junction of the epidermis and dermis

System P 2 (6 decks)

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