1 Flashcards
What skin disease is desired as a red macular, with a pale eroded center, with possible vesicles or bullae?
Erythema multiforme
What is the sign associated with seborrheic keratosis?
Lester-trelat sign (paraneoplastic syndrome)
What condition is assocaited with epidermal hyperplasia and dermal scaring?
Lichen simplex chronicus
What is the most common form of eczema ?
Allergic contact dermatitis
Does lichen planus self resolve?
Yes in about 1-2 years
Seborrheic dermatitis is also know as what?
Cradle cap
Dactylitis (sausage digits) is assocaited with what?
Psoriasis patients (35%)
High grade HPV infections are caused by what?
HPV-16 AND HPV 18
What condition begins as as fever and malaise, 24-48 hours. Macules and vesicles, most common in daycares?
Hand foot and mouth disease
What is a dysplastic lesion in areas of sun exposure with a “sand paper like” texture ?
Actinic keratosis
What is a condition of cumulative UV damage with purple macules?
Senline purpura
What is a sign associated with lichen planus>?
Wickhams striae (70% have oral involvement )
What what is urticaria?
Hives
What makes up chronic inflammatory dermatoses ?
Psoriasis, lichen planus, lichen simplex chronicus
Senile purpura effects ____%of every >than___years old?
25%, 90 years old
Dermatitis herpetiformis most commonly effects who?
20-40 year old males
IgE dependent = ?
Feature of common allergens
What are functions of the skin?
Barrier, prevents water loss, UV protection
What is a common Nevus?
Benign growth, in the dermis, well defined borders, sometimes called a beauty mark
What condition is raised itchy and scaly and caused by repetitive traum such as OCD, anxiety, depression ?
Lichen simplex chronicus
Most genital warts comes form what forms of HPV?
6, 11
What is the 3rd most common skin cancer?
Melanoma
Psoriatic Arthritis is also called wha?
Pencil in cup deformity
What is more common? Pemphigus vulgaris or pemphigus foliaceus?
Pemphigus vulgaris
What kind of boarder does melanoma have?
Notched
What are risks for lichen planus?
ARD, dry eyes, arsenic, HCV infxn
What is a dysplastic nevus?
Larger, various colors, irregular borders
What kind of lesion is associated with erythema multiform ?
Targetoid
What are the risks for acanthosis nigricans?
Diabetes, obesity and genetics
What condition is associated with a fishnet like pattern of IgG?
Pemphigus
What organism causes most (80%) of all impetigo infections?
Staph. Aureus
What does chronic eczema look like?
Scaling plaque
What is more common verruca vulgaris or verruca plana ?
Verruca vulgaris
What skin condition may disguise cancer, and the onset is after 40 ?
Solar lentigo
What condition is associated with a red rash with “honey colored crust”
Impetigo
Who does impetigo most commonly affect?
Children and adolescent athletes
What is an autoimmune skin condition that has T cells at the dermoepidermal junction?
Lichen Planus
Is seborrheic keratosis benign or malignant ?
Benign
Psoriatic arthritis occurs in what percent range or psoriasis patients?
5-30
Pemphigus affects what group of patients?
Middle aged or elderly females
Low grade HPV infections are caused by what?
HPV-6, HPV-11
Acute eczematous dermatitis is also know as what?
Eczema
What skin disease is desired as a red macular, with a pale eroded center, with possible vesicles or bullae?
Erythema multiforme
What is more severe acne vulgaris or cystic acne ?
Cystic
Are fungal infections itchy?
Yes INTENSLY ITCHY (pruritus)
What organism causes aspergillosis?
Aspergillus fumigatus
A familial dysplastic nevus has what kind of cancer risk?
Higher (melanoma)
Where does erythema multiform attack?
Junction of the epidermis and dermis
What gene/pathway is associated with basal cell carcinoma ?
PTCH (hedgehog pathway) and TP53
What type hypersensitivity is erythema multiform?
Type IV
What kind of sensitization is eczema ?
CD4+ T cells
What type of invention is warts (verrucae)
Viral
Pemphigus vulgaris is located where?
Skin and MUCOSA
What organism causes dermal abscesses?
Pseudomonas aeruginosa
What skin cancer effects adults and the elderly?
Melanoma
What are the causes of a dermal abscess?
Puncture wound or burn injury
Is a sebaceous adenoma benign or malignant ?
Benign
Which form of pemphigus is limited to skin?
Pemphigus foliaceus
Detachment of the nail (oncholysis) is found in who?
1/3 of psoriasis patients
What is the most common skin cancer ?
Basal cell carcinoma
Is dermatoheliosis caused by synthetic or natural exposure?
Both
What is more severe? Pemphigus vulgaris or pemphigus foliaceus?
Pemphigus vulgaris
What condition is described as having dark “coin like” lesions with a flat “stuck on” appearance ?
Seborrheic keratosis
Where does aspergilliosis typically begin?
Lungs, quickly spreads to the blood
What are symptoms of acne vulgaris?
Erythema, pustules, comedones with possible pain.
What is an example of a bacterial skin infection?
Impetigo and dermal abscesses
What skin disease is described as a red macular, with a pale eroded center, with possible vesicles or bullae?
Erythema multiforme
What type hypersensitivity is erythema multiform?
Type IV
Where is senile purpura most commonly seen?
Extensor surfaces
What two syndromes are associated with erythema multiforme major ?
Stevens-johnson syndrome, toxic epidermal necrolysis
A blockage/inflammation of pilosebaceous region is what?
Acne vulgaris
What type of erythema multiforme is drug related, and is more aggressive causing a sloughing of epidermis, fluid loss and infection?
Erythema multiforme Major
Hereditary angioedema is associated with that?
Urticaria
Where are common places for fungal infections?
Skin, NAIL BED
What is are another name for genital warts?
Condylomata acuminata
Are fungal infections superficial or deep? `
Superficial
What are 3 blistering (bullous) disorders
Pemphigus, bullous pemphigoid, dermatitis herpetiformis
What fungal infection is an immunodeficiency, highly angioinvasive.
Aspergillosis
What is a mild form of dermatitis that has patches of red skin, that are scaly, flaky, and itchy. ?
Seborrheic dermatitis
Xeroderma pingmentosa is assoscited with what?
Squamous cell carcinoma
Melanoma grows _____early, and _________late.
Radial, verticlql
Is impetigo contagious ?
Yes, very
Where does erythema multiform attack?
Junction of the epidermis and dermis
A firboepithelia polyp is known as what?
A skin tag (acrochordon)
Where are common locations of acanthosis nigricans?
In body folds ( axillae, groin, neck)
Where are common places for psoriasis ?
Elbow, knees, scalp, glans penis, intergluteal cleft.
Is erythema multi form rare
Yes
What is the atopic triad?
Dermatitis, asthma, rhinitis
What are treatments for psoriasis?
Methotrexate, cyclosporine, phototherapy (UBV)
Are warts self limiting?
Yes
Does most urticaria remain for a long time?
No, usually they develop and fade in a few hours
What kind of lesion is associated with erythema multiform ?
Targetoid
Urticaria is what type hypersensitivity ?
Type 1
Pemphius is what kind of hypersensitivity ?
type II
What condition affects patients with celiac disease?
Dermatitis herpetiformis
Bullous pemphigoid have what kind of pattern of IgG?
Linear
Urticaria effects people or what age and are they itchy?
20-40, yes.
Wheals (hives, or welts), round, red, swollen rash is associated with what?
Urticaria
What percent of squamous cell carcinomas metastasize to the lymph nodes
5%
Is impetigo painful??
No
What condition is a hyperplasia of melanocytes, that are small brown macules?
Solar lentigo
What does acute eczema look like?
Red, vesicles, oozing, crusts
Is a dermal abscesses a shallow or deep infection?
Deep
What kind of lesion is associated with erythema multiform ?
Targetoid
What is the second most common skin cancer?
Squamous cell carcinoma
Auspitz sign is assocaited with what?
Psoriasis
A sporadic dysplastic nevus has what kind of cancer risk?
Low
IgE independent = ?
ADR to opiates or antibiotics
Blisters in pemphigus foliaceus are________?
Subcorneal
Acne is most common in who during adolescence? Adults?
Males. Adults-females
What is the mutation that causes seborrheic keratosis?
FGFR3 mutation
What type of erythema multiform is post infection ( HSV, Fungi) and is a more mild version?
Erythema multiforme MINOR
Melanomas has what kind of appearance ?
STRIKING VARIATION
What kind of hypersensitivity is eczema ?
Type 1 and type IV
What is a flesh toned lesion coated on the head or neck that is slow growing and is more a a consmetic problem than anything?
Sebaceous adenoma
What are the 6ps got lichen planus ?
Pruritic, purple, polygonal, planar, papules, plaque
A well demarcated lesion, that is pink to salmon colored covered by a flaky silver-white score is associated with what?
Psoriasis
What kind of eczema is from a genetic risk, that is a childhood onset and imprecise with age?
Atopic dermatitis
What is an autoimmune condition, of unknown antigens, t cells in the epidermis, affects 2% of the population and is itchy and life long?
Psoriasis
Telangiectasia and pyramidine diners are assocaited with what?
Dermatoheliosis
Melanoma is much more likely is someone has how may dysplastic nevi?
> or equal to 10
What condition is asymptotically hyper-pigmentation of the skin that has a dark “velvety” appearance?
Acanthosis nigricans
Dermatoheliosis is the result of what?
Uva and uvb exposure
What type hypersensitivity is erythema multiform?
Type IV
What are some different names for fungal infections?
My oasis, dermathophytosis, tinea “ring worm “
Acne vulgaris affects what percent of the population? Severe?
80%, severe 20%
Which skin condition do some consider squamous cell carcinoma in situ?
Actinic keratosis
Hand foot and mouth disease is an infection with what?
Coxsackievirus
Blisters of bullous pemphigoid are________?
Subepidermal
In pemphigus vulgaris blisters are________?
Suprabasil
What is a syndrome associated with acanthosis nigricans?
Paraneoplastic syndrome
What kind of acne is large, filled with edema, pus, and more likely to produce scaring?
Cystic acne
Where does erythema multiform attack?
Junction of the epidermis and dermis
