1-5 Cells & Tissues of the Immune Response Flashcards
Name the primary and secondary immune organs
Primary:
Thymus
Bone marrow
Secondary:
lymph nodes, spleen
What is the name of the cell type:
Lymphocytes produced in the thymus that place an active role in cell-mediated immunity
T Cells
What is the name of the cell type:
Lymphocytes produced in the bone marrow that are heavily involved in humoral immunity
B cells
What is the name of the cell type:
large cells that play a role in innate immunity by phagocytizing unhealthy and non-self cells
Macrophage
What is the name of the cell type:
Leukocytes that travel to sites of infection in response to inflammation and differentiate into macrophages and dendritic cells
Monocytes
What is the name of the cell type:
One of the first cells in circulation to interact with bacteria. Kills by phagocytosis.
Also known as polymorphonuclear lymphocytes (PMNs)
Neutrophils
What is the name of the cell type:
kills antibody-coated parasites through release of granule contents
Eosinophils
What is the name of the cell type:
Regulate immune response to parasites
Basophils
What is the name of the cell type:
Expel parasites through release of histamine and other active chemicals
Mast cells
In which ways are these immune cell types identified or described?
Morphological criteria: stains acidic or basic, then morphology is noted (cell shape, size, nuclear shape)
Antigenic Criteria: Identifies cells based on antibody recognition of antigens present on their surface….the cluster of differentiation (CD) is used to organize the antigens
Which type of immunity (innate/adaptive) is characterized by a rapid response, a fixed response, has limited number of specificities, and is constant during response?
Innate immunity
Which type of immunity (innate/adaptive) is characterized by a slower variable response (days to weeks), highly selective specificities, and improves during response?
Adaptive immunity
What is meant by the word opsonize and what are two examples of opsonins?
An opsonin is an antibody or other substance that binds to foreign microorganisms or cells, making them more susceptible to phagocytosis
Examples: Complements or antibodies
Which cell type is the most abundant leukocyte (white blood cell)?
Neutrophils (polymorphonuclear leukocytes)
about 60-70% of all circulating WBCs
which cell type differentiates into macrophages upon entering into tissues and become better effector cells?
Monocytes
