1 Flashcards

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1
Q

What skin side effects can lithium cause?

A
  • Acne
  • Psoriasis
  • Alopecia
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2
Q

What’s the difference between attachment and bonding

A

Attachment- emotional dependence of infant on its mother

Bonding - mother’s feelings for infant

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3
Q

best test for Huntington’s

A

PCR (to examine trinucleotide repeats)

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4
Q

which frontal lobe region causes personality characteristics of being profane, irritable, irresponsible?

A

orbitofrontal

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5
Q

which frontal lobe region causes apathy?

A

medial frontal lesion

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6
Q

Difference of cohort versus case control study

A

Case control study - Start with an outcome and go back in time to study the risk factor.

Cohort study - Start with risk factor and see who developed the disease and who did not.

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7
Q

What is this: mental confusion, opthalmolpegia, gait ataxia

A

Wernicke’s encephalopathy

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8
Q

Where are the lesions in Wernicke’s encephalopathy

A

microhemorrhages in periventricular gray matter around aqueduct of 3rd and 4th ventricles

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9
Q

Can lithium be given with MAOIs?

A

Yes

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10
Q

Can meperidine be given with MAOIs?

A

no

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11
Q

How long of a washout of SSRIs before giving MAOIs

A

14 days (28 for fluoxetine)

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12
Q

What is the inheritance pattern of Hungtinton’s

A

Autosomal dominant

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13
Q

Difference of primary vs secondary vs tertiary prevention

A

Primary - prevent onset of dz

Secondary - identify dz in early stages

Tertiary - reduce deficits of dz in later stages to prevent dysfunction

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14
Q

Which neuromuscular dz associated with small cell lung cancer?

A

Lambert Eaton

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15
Q

what degenerates in ALS

A

upper and lower motor neuron cells (anterior horn cells)

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16
Q

what is 1st and 2nd line tx for absence seizures

A

1st - ethosuximide

2nd - depakote

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17
Q

time criteria for insomnia disorder

A

3 nights/week for 3 months

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18
Q

Tuberous sclerosis charactersitcs

A

seizures, retardation, behavioral problems, cutaneous lesions (ash leaf, shagreen spots), retinal hemorrhages

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19
Q

Memantine MOA

A

NMDA antagonist

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20
Q

do antipsychotics and ritalin increase or decrease TCA concentration?

A

increase

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21
Q

Gerstmanns syndrome is a lesion where?

A

left parietal lobe damage

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22
Q

classic tetrad of Gerstmann’s syn

A

acalculia, agraphia, right and left confusion, finger agnosia

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23
Q

Can EEG have spontaneous activity in brain death?

A

Apparently yes

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24
Q

Test for myasthenia gravis

A

Edrophoniium chloride (Tensilon)

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25
Q

Gower’s maneuver seen in

A

Duchenne’s muscular dystrophy

26
Q

classic picture of giant cell arteritis ((vascuitis)

A

new onset HA, fever, nightsweats, weight loss, jaw claudication, polymalgia rheumatica (25%) in older women. Retinal artery occlusion can happen

27
Q

test for giant cell arteritis

A

serum ESR

28
Q

MAOI washout period for bupropion

A

14 days

29
Q

can you combine lithium and MAOI?

A

yes

30
Q

older person gets prescribed SSRI and develops disorientation, nausea, weakness. What’s happened?

A

SIADH

31
Q

Sleep patterns in depression on EEG

A

shortened REM latency
increased REM density
decreased IV sleep

32
Q

most significnt genetic risk factor for Alzheimer’s dz

A

homozygosity for inheritance of E4 allele of apo E (chrom 19)

33
Q

female orgasmic disorder is absence of orgasms what % of the time?

A

75-100%

34
Q

which anticonvulsant causes hirsutism, facial dysmorphism, gingival hypertropy, and cerebellar atrophy (ataxia)

A

phenytoin

35
Q

xyrem treatment for

A

cataplexy associated with narcolepsy (analogue of date rape drug)

36
Q

chronic fatigue syndrome timeline

A

fatigue for over 24 hrs for 6 months

37
Q

4 Piaget stages

A

1) sensorimotor
2) perioperational
3) Concrete operations
4) formal operations

38
Q

What Piaget stage is conservation?

A

concrete

39
Q

What Piaget stage is object permanence

A

Sensorimotor

40
Q

short palpebral fissures a result of what

A

fetal alcohol syndrome or William syn

41
Q

At what age would child tolerate mother’s absence without distress in secure attachment?

A

25 months

42
Q

What age is stranger anxiety

A

8 months-2 years

43
Q

Which MAOI works on MAOB at lower doses?

A

Selegeline

44
Q

Pergolide MOA and use

A

dopamine agonist - used in Parkinson’s

45
Q

What’s the only atypical antipsychotic that blocks serotonin and NE reuptake and blocks 5HT 1A receptor?

A

Ziprasione

46
Q

difference of effect of right versus left prefrontal cortex on mood

A

left activated - elevate mood (lesion–> depression)

right activated - depressed mood (lesion –> euphoria)

47
Q

most common cause of intracerebral hemorrhage

A

HTN

48
Q

type I error

A

null hypothesis was rejected when it should have been retained (difference only exists due to chance, false positive)

49
Q

type 2 error

A

null hypothesis retained when it should have been rejected (false negative)

50
Q

What is the probability of finding the difference between 2 samples

A

power

51
Q

PCP can be found in urine for how long?

A

till 8 days

52
Q

Cocaine can be found in urine for how long?

A

8 hrs

53
Q

heroin can be found in urine for how long?

A

72 hrs

54
Q

test of choice to diagnosed CJD?

A

LP and CSF assay for 14-3-3- and tau proteins

55
Q

What eye finding found in schizophrenia

A

abnormal smooth pursuit and saccades

56
Q

which mental health disorder has highest prevalence

A

anxiety disorders

57
Q

biggest comorbidity with gambling d/o

A

MDD

58
Q

which drug can cause dementia

A

inhalants

59
Q

LSD MOA

A

partial agonist at postsynaptic serotonin receptors

60
Q

which mental health disorder is most likely to be violent?

A

substance abusers

61
Q

what’s a characteristic of NF-2 but not NF-1

A

bilateral schwannomas