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Nervous System > 04.1 Neural Basis of Pain > Flashcards

04.1 Neural Basis of Pain Flashcards

1
Q

What are the two types of nociceptive fibre?

A

A delta fibres - myelinated (sharp pain)

C fibres - unmyelinated (dull pain)

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2
Q

Why does rubbing a painful area help stop the pain?

A

Mechanoreceptors on the skin activate the substantia gelatinosa (of the second lamina of the dorsal horn). This then inhibits the ascending pain pathways.

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3
Q

What is the descending inhibitory pathway of pain?

A

Fibres from the pariaqueductal grey in the midbrain active pathways in the reticular formation which activate the substantia gelatinosa which inhibits pain pathways. The PAG neurones are sensitive to opioids.

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4
Q

What are some weak opiates?

A

Codeine

Tramadol

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5
Q

What are some strong opiates?

A

Morphine
Diamorphine
Oxycodeine
Fentanyl

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6
Q

What are some adjuvant analgesics?

A

NSAIDs
Paracetamol
Cannabis
Ketamine

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Nervous System (20 decks)

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