04 NEOPLASIA

Question 1

6 definitions of Neoplasia

Answer 1

Tumor
Purposeless
Newgrowth
Abnormal Mass 
Autonomous growth
Monoclonal

Question 2

Means the process of “new growth”

Answer 2

Neoplasia

Question 3

A new growth is called _______

Answer 3

Neoplasm

Question 4

Neoplasm is commonly known as?

Answer 4

Tumor

Question 5

The study of tumors or neoplasms

Answer 5

Oncology

Question 6

Common term for all malignant tumors

Answer 6

Cancer

Question 7

The Latin word “cancer” means?

Answer 7

Crab

Question 8

Abnormal mass of tissue

Answer 8

Neoplasm

Question 9

Genetic changes allow excessive and unregulated proliferation that becomes _______________

Answer 9

autonomous

Question 10

Entire population of cells within a tumor arises from a _______ cell that has incurred a genetic change (clonal)

Answer 10

single

Question 11

Two basic components of tumors

Answer 11

Parenchyma

Stroma/ Non-neoplastic stroma

Question 12

determines the biologic behavior of the noeplasm

Answer 12

Parenchyma

Question 13

A basic component made up of connective tissue and blood vessels

Answer 13

Stroma / Non-neoplastic stroma

Question 14

It is the component from which the tumor derived its name

Answer 14

Parenchyma

Question 15

a benign tumor arising in fibrous tisssue

Answer 15

fibroma

Question 16

Benign tumors are designated by attaching the suffix “ _____”

Answer 16

-oma

Question 17

A benign cartilaginous tumor

Answer 17

Chondroma

Question 18

Nomenclature of benign __________ tumors is more complex

Answer 18

epithelial

Question 19

Lab Diagnosis of Cancer

Answer 19

Pap's smear
Histologic and Cytologic methods
Fine Needle ASpiration BIopsy
Frozen SEction
Excision and Incision Biopsy
Biochemical Assays - tumors markers
Immunohistochemistry 
Flow Cytometry
Electron Microscopy
Tissue Culture

Question 20

As a guide for treatment: lower grades are amenable to?

Answer 20

Surgery

Question 21

AS a guide for treatment: higher grades are amenable to?

Answer 21

Radiation

Question 22

As a prognostic guide - the (a.lower b.higher) grades have generally a poorer prognosis.

Answer 22

b.higher

Question 23

True or false. Undifferentiated tumors are less malignant than well-differentiated tumors.

Answer 23

False

Question 24

(a. Differentiated cells b.Undifferentiated cells) - resembling normal cells

Answer 24

2. Differentiated

Question 25

Undifferentiated cells are (a.younger forms b. normal forms c. older forms)

Answer 25

a. younger forms

Question 26

Give the stage. More distant lymph node involvement

Answer 26

N3

Question 27

Give the stage. Distant metastases present

Answer 27

M1

Question 28

Give the stage. No distant metastases

Answer 28

M0

Question 29

Give the stage. In situ, non-invasive (confined to epithelium)

Answer 29

Tis

Question 30

Give the stage. Small, minimally invasive within primary organ site

Answer 30

T1

Question 31

Give the stage. Larger and/or invasive beyond margins of primary organ site

Answer 31

T3

Question 32

Give the stage. Very large and/or very invasive, spread to adjacent organs

Answer 32

T4

Question 33

Give the stage. Regional lymph node involvement

Answer 33

N1

Question 34

Give the stage. Extensive regional lymph node of involvement

Answer 34

N2

Question 35

Give the stage. No lymph node involvement

Answer 35

N0

Question 36

Larger, more invasive within the primary organ site

Answer 36

T2

Question 37

The most common systems for staging employs the ____ classification

Answer 37

TNM

Question 38

A "___" score is based upon the size and/or extent of invasion.

Answer 38

T

Question 39

The "___" score indicates the extent of lymph node involvement.

Answer 39

N

Question 40

The "___" score indicates whether distant metastases are present.

Answer 40

M

Question 41

Based on the degree of differentiation of tumor cells and the number of mitoses

Answer 41

Grading

Question 42

Based on the size of the primary lesion, extent of spread to regional lymph nodes, presence or absence of metastases.

Answer 42

Staging

Question 43

Expansile growth can destroy adjacent structures, endocrine gland neoplasm elaborate hormones

Answer 43

Local and hormonal effects

Question 44

Progressive loss of body fat and lean body mass accompanied by weakness, anorexia and anemia

Answer 44

Cancer cachexia

Question 45

Symptom complexes in cancer patients that cannot be readily explained

Answer 45

Paraneoplastic syndromes

Question 46

Causative agent of squamous papillomas (warts)

Answer 46

Human papilloma virus

Question 47

Causes gastric carcinoma and gastric lymphoma

Answer 47

Helicobacter pylori

Question 48

Carcinogenic agent of hepatocellular carcinoma

Answer 48

Hepatitis B virus

Question 49

Diseases caused by Epstein-Barr virus

Answer 49

Burkitt lymphoma | Nasopharyngeal carcinoma