0.3 DSA Intro to Autonomics Pharmacology

Question 1

What are the general effects of α1 receptors?

Answer 1

Vascular smooth muscle contraction

Question 2

What are the general effects of α2 receptors?

Answer 2

Decreased insulin secretion
Decreased NE secretion
Smooth muscle contraction

Question 3

What are the general effects of β1 receptors?

Answer 3

Increased force/rate of heart contraction and AV nodal conduction velocity

Question 4

What are the general effects of β2 receptors?

Answer 4

Vascular relaxation
Bronchial relaxation
GI/GU smooth muscle relaxation

Question 5

What are the general effects of β3 receptors?

Answer 5

Lipolysis

Only found on adipose tissue

Question 6

What are the general effects of D1 receptors?

Answer 6

Vasodilation
Natriuresis
Diuresis

Question 7

What are the general effects of muscarinic receptors?

Answer 7

Smooth muscle contraction
Decreased heart rate

(parasympathetic)

Question 8

Smooth muscle of blood vessels are not innervated by parasympathetic neurons. How do they vasodilate?

Answer 8

Once receptor is activated, the release of EDRF (NO) is triggered. This directly leads to vasodilation.