01-15: Transport of Gametes Flashcards
What is the status of the graafian follicle at pre-ovulation?
mature graafian follicle
What is the status of the oocyte at pre-ovulation?
oocyte arrested in Diplotene of Prophase I
What causes expansion of the follicle at pre-ovulation?
FSH and LH
What is the status of the oocytes progress through Meiosis I and II at pre-ovulation?
- Meiosis I = complete
- Arrested at Metaphase II
What is the status of the stigma at pre-ovulation?
formation of stigma
What happens pre-ovulation?
1- Mature graafian follicle 2- Oocyte arrested in Diplotene of Prophase I 3- Expansion of follicle by FSH and LH 4- Completion of meiosis I 5- Arrest at metaphase II 6- Formation of stigma
What happens at ovulation (Day 14)?
1- LH surge from anterior pituitary
2- Increased blood flow to follicle wall
3- Thickening of outer layers of follicle
4- Release of fluid/other compounds from BV
5- Local production of matrix metalloproteinases
6- Secretion of HA from cumulus cells
7- Inflammatory action (rupture of follicle wall)
What are the fluids and other components that are released at ovulation from BV?
- Edema
- Prostaglandins
- Histamine
- Vasopressin
- Plasminogen activator
What do the matrix metalloproteinases do?
degrade extracellular matrix
When does the inflammatory action causing rupture of follicle wall occur during ovulation?
about 24 hours after the LH surge
What is ovulated?
- Ovum at Metaphase II
- ZP
- Corona radiata
- Expanded cumulus oophorus
What happens when the fimbriae of the uterine tube move closer to the ovary and sweeps across the surface?
- Ciliation of tube epithelial cells INCREASES
- Activity of tubal smooth muscle cells INCREASES
What transports the egg through the uterine tube?
contractions of smooth muscle
How long does it take the egg to transport through the ampulla?
72 hours (slow transport)
How long does it take the egg to transport through the isthmus?
8 hours (rapid transport)
What does the rapid transport of the egg through the isthmus require?
progesterone
How many days does it take the egg to arrive at the uterus?
3-4 days
How many days for:
- Implantation
- Blastocyst
- Morula
- Cleavage
- Implantation = 6 days
- Blastocyst = 4 days
- Morula = 3 days
- Cleavage = 1 day
After spermiogenesis, what 3 kinds of transport does the sperm use?
- passive transport (via testicular fluid)
- smooth muscle contractions
- seminiferous tubule cilia
Where does the sperm travel through after spermiogenesis?
- Through Rete testes (network of tubules)
- Through Efferent ductules (Efferent pathway)
- To Head of epididymis (highly coiled)
What are the steps of sperm transport in the male?
1- Passive transport to Epididymis via testicular fluid
2- Maturation in Epididymis (2 weeks)
3- Rapid transit through Ductus Deferens
4- Addition of fluid from Seminal Vesicle
5- Addition of Prostatic fluid