김하영 Flashcards by 하영 김

Q

accelular infecious agent

A

virus

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Q

the smallest

A

piconavirus

piconaviridae

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Q

the largest

A

poxviridae

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Q

range of size

A

0.02-0.3 micrometers

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Q

obligate intracellular parasite 3개

A

Rickettsia
Chlamydia
Virus

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Q

obligate intracellular parasite 특징

A

no built in metabolic machinery

no ribosome > no enzyme( rickettsia 는 있다)

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Q

complex nucleocapsid

A

bacteriophage

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Q

hlical nucleocapsid

A

ebola, influenza(enveloped), tobacco mosaic

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Q

polyhedral nucleocapsid (icosahedral)

A

mastadenovirus

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Q

tails

A

bacterial viruses, bacteriophages

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Q

envelopes

A

animal viruses

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Q

hemagglutination assay

A

highest dilution clump RBC

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Q

plaque assay

A

on host cell, PFU

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Q

infectious dose, lethal dose

A

smallest amount to kill 50% > ID50

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Q

lytic bacteriophages

A

attachment
penetration
biosynthesis
maturation ( tail > capsid > tail fiber )
release

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Q

lysogenic multiplication

A

attachment
penetration
DNA recombination
lysogenic bacteria reproduce
prophage DNA recombination 분리
go to lytic cycle

Q

animal viruses

A

attachment, adsorption
penetration
uncoating of viral nucleic acids
biosynthesis
maturation, assembly of virus capsids
virus release

Q

animal virus attachment

A

receptor

Q

animal virus penetration -fusion

A

HIV, herpes

Q

endocytosis - enveloped

A

adenovirus, influenza virus

Q

budding release

A

enveloped - influenza, HIV

Q

chronic virus infection

A

always detectable

mild, absent for long period

Q

latent virus infection

A

stops reproducing, remain dormant

not detectable

Q

latent virus 종류

A

Herpes simplex type 1 - cold scores

Varicella zoster virus - chicke pox, shingles

Q

slow virus

A

measles virus, HIV infections

Q

oncogenes

A

tumor, integrated into host cell DNA

Q

Epstein- Barr virus

A

oncogene
Burkitt’s lymphoma
nasopharyngeal carcinoma

Q

Hepatitis B virus

A

liver cancer > oncogene

Q

Hepatitis C virus

A

liver cancer > oncogene

Q

Human herpesvirus 8 HIV

A

Kaposi’s sarcoma > oncogene

Q

human papillomavirus

A

cervical cancer > oncogene

Q

HTLV-1, HTLV-2

A

leukemia > oncogene