Direct-contact diseases Flashcards
Direct contact bacteria
Gas gangrene B streptococcal diseases Inclusion Conjunctivitis Leprosy Peptic ulcer gastritis Staphylococcal disealse bacterial vagionosis Gonorrhea Syphilis Tetanus Trachoma
S. epidermis
3. directi bac non pigmented upper respiratory hemolysins, enterotoxin, catalase, coagulase, leukocidin Toxic shock syndrome TSS- tempon
S. aureus
3. direct bac yellow-pigment pyogenic-pus forming hemolysins, enterotoxin, catalase, leukocidin, coagulase Toxic shock syndrome TSS- tempon
STDs
Gonorrhia - Neisseria gonorrhoeae
Syphillis - Spirocheta, Treponema pallidum
Chlamydia- a bacterium, Chlamydia trachomatis
Trichomoniasis - a protozoan, Trichomonas vaginalis
tetanus
- direct - soil
Clostridium tetani
tetanus toxin- neurotoxin
neurotoxin
inhibitory interneurons 차단- 근육 계속 수축하고 있음
Cold sores 단순포진
- direct virus - oral
HHV-1(HSV-1)- enveloped, icosahedral
gingivostomatitis
herpetic keratitis
latency
Genital Herpes
- direct virus - genital, 출산
HHV-2
acyclovir
blisters, fever, latent
EBV
- direct : mouth to mouth, saliva
HHV4 - gamma = Epstein- Barr virus
epithelial of oropharynx, parotid gland, B cells
> enlarged lymphnodes, spleen, sore throat, headache, nausea
EBV clinical spectrum
infecious mononucleosis
oral hairy leukoplakia
Burkitt’s lymphoma
Nasopharyngeal carcinoma
Cytomegalovirus Inclusiosn Disease
- direct- semen, cervical solution, 수혈, 장기이식
HHV-5/ HCMV (human cytomegalovirus)
causes form of intranuclear inclusion bodies
latent
usually asymptomatic
hepatitis, fever, lymphacytosis,
monoculeosis - like illness
Sixth disease
- direct virus- saliva
HIV-6, 7 : Roseolovirus
tropism : 면역이랑 상피
exanthem subitum : 돌발성 발진 roseola infantum : 영아 장미진 pneumonitis chronic fatigue sydrome lymphadenitis multiple sclerosis
HIV
3.direct virus: 점막 접촉, 피 혹은 정액,
HIV1, HIV2 > Retroviridae, Lentivirus > AIDS
ssRNA + reverse transcriptase (virus효소)
co-infection with oncogenic DNA
EBV(4), KSHV(8), HPV
*Kaposi’s sarcoma (KS) most common tumor
leukocyte 에 부착
HIV 점염 과정
reverse transcriptase > Integrase > transcription > …
Leukemia
bone marrow, lymph system, spleen
all age group
dysfuntional cell
adult is 10 times more than children