airborne Disease Flashcards

1
Q

airborne spread

A

droplet - coughing, sneezing, talking,

where - respiratory, some skin

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2
Q

nasal cavity

A

Staphylococcus aureus

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3
Q

Oral cavity

A

Neisseria meningitidis

streptococcus pyogenes

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4
Q

Pharynx

A

Corynebacterium diphteriae

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5
Q

Larynx

A

Haemophilus influenzae

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6
Q

primary bronchus

A

influenza virus

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7
Q

secondary bronchus

A

coccidioides immitis

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8
Q

Terminal bronchus

A

streptococcus pneumoniae

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9
Q

alveolar sacs

A

Coxiella burnetii

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10
Q

alveoli

A

Chlamydia psittaci

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11
Q

upper respiratory tract

A
stapylococcus aureus
Neisseria meningitides
streptococcus pyogenes
Corynebacterium diphtheria 
haemophilus influenzae
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12
Q

lower respiratory tract

A
coccidioides immitis
bordetella ertussis
streptococcus pneumoniae
coxiella burnetii
chlamydia psittaci
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13
Q

streptococcal disease

A

streptococcus pyogenes

streptococcus pneumoniae

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14
Q

s. pyogenes

A
  1. airborne bacteria
    패혈성 인두염 strep throat

구강점막 심한 염증, 미열, 전신 피로감, 농가진
성홍열, 류마티스열 발전 가능

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15
Q

s. pneumoniae

A
  1. airborne bacteria
    균혈증

주로 2차 감염 : 폐 > 균혈증
내이감염, 심내감염
미치료시 30%치사율

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16
Q

diphtheria

A
  1. airborne disease
    Cornebacterium diphtheriae

pseudomembrane > 질식
diphtheria toxin > ptn

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17
Q

Corynebacterium diphtheriae

A
  1. airborne bacteria

G+
불규칙 막대

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18
Q

diphtheria toxin

A

ptn 합성 저해 (A-B)

EF-2효소 불활성화 by A

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19
Q

Bordetella

A
  1. airborne disease 백일해

Bordetella pertussis

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20
Q

Bordetella pertussis

A
  1. airborne bacteria
    G-
    작은 구
21
Q

Neisseria

A
  1. airborne disease 수막구균혈증

Neisseria meningitidis

22
Q

Bordetella 증상

A
백일해 whooing cough
급성 고점염성 호흡기 질병
6주 반복 돌발 기침
exotoxin > 숙주 조직 손상
endotoxin 도 증상 영향
23
Q

Neisseria 증상

A

meningococcemia 수막구균혈증
닫힌 집단 점염병
균혈증, 상기 > 패혈증, 혈전, 쇼크, 10%사망

24
Q

Neisseria meningitidis

A
  1. airborne bacteria - 수막구균혈증

G-

25
Q

Legionellosis

A
  1. airborne 냉방병

Legionella pneumophila

26
Q

Legionellosis 증상

A

냉방병

습한 에어로졸 공기 > 물방울 감염
사람 to 사람 x
식세포 단핵세포 내부에서 생장

27
Q

Legionellosis 고위험군

A

당뇨
만성폐질환자
흡연자
면역억제제 사용자

28
Q

Mycobacterium tuburculosis

A
  1. airborne bacteria - 결핵

G+
증식 느려 > 항생제 내성
혈류, 임파선, 기관들, 특히 폐

29
Q

Mycobacterium leprae

A
  1. bacteria - 나병

1873 Hansen, 인공배지에서 배양 x 유일

30
Q

leprae

A

mycobacterium
airborne 이 설득력이 있으나 아직 밝혀지지 않음
안면과 사지에 lesion
심하면 말초 파괴 운동성 상실

31
Q

airborne bacteria 6gae

A
Diphtheria
Legionellosis
Meningitis
Tuberculosis
Pertussis
Streptococal diseases
32
Q

airborne virus 5gae

A
chickenpox
shingles
smallpox
Measles
Influenza
33
Q

chicken pox

shingles

A
  1. airborn virus - droplet inhalation
    chicken pox- Varicella
    Shingles - Herpes Zoster
34
Q

chicken pox

A
  1. airborn virus - Varicella 수두

HHV-3 = VZV
알파

35
Q

shingles

A
  1. airborn virus - herpes zoster
    reactive of chickenpox
    HHV-3= VZV
    latent in nerve ganglia
36
Q

treatment of HSV, VZV

A

guanine, acyclovir

chickenpox attenuated virus vaccine available

37
Q

acylovir

A

HSV, VZV > virus DNA polmerase 비가역적 결합

38
Q

smallpox

A
  1. airborne virus 천연두 - 사람만
    Variola major, Vaiola minor virus
    orthopoxvirus(genus), Poxviridae(family)
39
Q

smallpox 전파

A
  1. inhalation of airborne variola virus
  2. prolonged face-to-face contact
  3. direct contact - fluid, bed, cloth
40
Q

smallpox chickenpox

A

small 팔다리 chicken가슴살

41
Q

Measles ( Rubeola )

A
  1. airborn virus -홍역
    Morbilivirus
    호흡기, droplet 전파
    attenuated vaccine
42
Q

attenuated vaccine

A

MMR, measles, mumps, rubella

43
Q

influenza (flu)

A
  1. airborne virus

RNA viruses, Orthomyxoviridae

44
Q

influenza classification 기준

A

Hemagglutinin(HA) / neuraminidase(NA)
> mem. glycoproteins

H5N1 조류독감: initiate another flu

45
Q

influenza A

A
  1. wild aquatic
  2. most virulent 맹독의
  3. subdivided on antibody response
46
Q

influenza B

A

exclusively human

47
Q

influenza C

A
  1. human, dog, pig

2. less common

48
Q

common influenza ABC 비교

A

A> B> C

49
Q

Flu

A

type/ geo지역/ strain #/year isolation/(HA-NA)

A/Fujian/411/2002 (H3N2)