分生 Flashcards

1
Q

暗示蛋白質可能不是遺傳物質

A

Griffth

Streptococcus pneumonia

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2
Q

證實轉型物質是DNA

A

Avery

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3
Q

賀雪 蔡司

A

標定32P-DNA 35S-蛋白質

T2 phage 的遺傳物質是DNA

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4
Q

半保留

A

Meselson Stahl

用15N追蹤DNA

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5
Q

DNA 複製

Helicase

A

Unwind 雙股螺旋

斷氫鍵

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6
Q

DNA 複製

Gyrase

A

break DNA超螺旋

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7
Q

DNA 複製

SSB

A

與單股DNA 結合

避免形成雙股

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8
Q

DNA 複製

Primase

A

合成RNA primer

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9
Q

DNA 複製

DNA pol3

A

延長核苷酸鏈

填補小gap

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10
Q

DNA 複製

DNA pol1

A

移除Primer

填補nick & gap

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11
Q

DNA 複製

Ligase

A

連接DNA 片段

形成磷酸雙脂鍵

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12
Q

真核聚合酶

Primase-合成primer

A

DNA pol a

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13
Q

真核DNA pol都具有3-5外切
5-3聚合
只有哪個沒有3-5外切活性?

A

DNA pol B

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14
Q

真核聚合酶

在粒線體中

A

DNA pol r

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15
Q

DNA pol 合成延滯股

A

DNA pol delta

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16
Q

Dna pol合成領先股

A

DNA pol epsilon

17
Q

DNA repair 的 pol

A

DNA pol B+epsilon

18
Q

畢德 特吞

A

一基因對應一酵素

紅麵包酶

19
Q

搖擺效應

A

不同mRNA 對應相同tRNA

差在第三鹼基

20
Q

i 對應?

A

A U C

❌i 不與G對應

21
Q

snRNA

A

spliceosome

剪核中的pre-mRNA

22
Q

snoRNA

A

剪接處理核仁中的pre-rRNA

23
Q

RNA 含量最多

A

rRNA

24
Q

RNA 種類最多

A

mRNA

25
Q

RNA 修飾最多

A

tRNA

26
Q

SRP RNA

A

co-translational sorting

27
Q

Silent muta

A

緘默

突變後胺基酸與原先雷同 終產物不見得影響

28
Q

Missense muta

A

誤義

突變後的密碼子仍對應胺基酸 但不見得代表正確意義

29
Q

Nonsense muta

A

無意義

轉為終止密碼 轉譯提早結束

30
Q

RNA聚合酶與?結合 進行轉錄

A

Promoter啟動子

31
Q

Repressor 與?結合

A

Operator 操作子

32
Q

HTH

A

最常見

Ex: CRP, 真核的homeodomain protein, 病毒的cro-protein

33
Q

Zinc finger

A

存在DNA binding protein

Ex:固醇類

34
Q

HLH

A

Ex:免疫系統蛋白, Myo D protein