Zoos Flashcards

1
Q

Ddx of purulent inguinal nodes?

A

(BCLAT)Bartonella Henslae, Tick borne tularemia (glandular), Chancroid, staph aureus, lymphogranuloma venereium

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2
Q

Clinical findings, tx, of cat scratch disease?

A

B.Henselae with 80% <21 year old acute suppurative lymphadenitis proximal to bite, scratch, lick of young cat. Can see encephlaitis, stellate retinitis (lipid exudates forming macular star on optho). Tx with azithromycin

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3
Q

microbiological features of bartonella?

A

slow growing weakly gram negative rod

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4
Q

Clinical features of B.Bacilliformis?

A

Andes, Peru, sand fly bite. Oroya fever(initial)–>verruga peruana (hemangioma- like nodules in skin/mucous membranes). Tx: Ciprofloxacin (Oroya); Azithro (vp)

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5
Q

What would you see on biopsy for cat scratch lymphadenopathy?

A

lymph node shows central abscess formation surrounded by palisaded histiocytes

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6
Q

what does bartonella quintana do/vector?

A

Pediculus humanus var. corporis causing bacteremia in the homeless, endocarditis, trench fever - The disease is classically a five-day fever of the relapsing type, rarely exhibiting a continuous course. The incubation period is relatively long, at about two weeks. The onset of symptoms is usually sudden, with high fever, severe headache, pain on moving the eyeballs, soreness of the muscles of the legs and back, and frequently hyperaesthesia of the shins.

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7
Q

what are the HIV associated bartonella species?

A

Bacillary cutaneous angiomatosis (henselae or quintana), Bacillary peliosis (henslae), lytic osteomyelitis (quintana),

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8
Q

features of bacillary peliosis?

A

caused by b.Henslae, also known as hepatosplenic bacillary peliosis. See on CT hypodense center +/- contrast enhancing rim with blood filled spaces on warthin starry stain. Peliosis hepatis is an uncommon vascular condition characterised by multiple, randomly distributed, blood-filled cavities throughout the liver

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9
Q

skin finding for anthrax?

A

pruritic paule on skin with ulceration, little vesicules form around ulcer.

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10
Q

microbio features of anthrax?

A

aerobic encapsulated gram positive bacilli

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11
Q

microbio features associated with tularemia?

A

GN cocobacillus

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12
Q

who gets Tularemia?

A

farmers, veterinarians, hunters skinning animals

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13
Q

what symptoms is suggestive of tularemia?

A

ulceroglandular>glandular»oculoglandular, pharyngeal, typhoidal, pneumonic

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14
Q

who gets pneumonic tularemia?

A

bioterroism, landscapers, mowers

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15
Q

how would you diagnose tularemia?

A

via serology. needs chocolate agar

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16
Q

tx of tularemia? prophylaxis drug?

A

streptomycin, gentamycin, cipro in milder case. Prophylaxis is with doxycycline

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17
Q

vector/host for plague?

A

rodent flea bite/praire dogs

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18
Q

Endemic plague locations?

A

New Mexico, California, Arizona, colorado

19
Q

symptoms of plague?

A

fever, nausea, swollen painful lymph nodes

20
Q

microbio of the plague?

A

yersinia pestis is a gram negative coccobacillus with bipolar staining bacilli with safety pin appearance

21
Q

treatment of plague?

A

streptomycin»doxy,cipro

22
Q

how do you get leptispirosis?

A

spirochetes excrete in urine, survive in water. Exposed intact skin to animal urine (cow, pigs, dogs, racoons, rats, mice) in summer and early fall

23
Q

Key symptoms of leptospirosis?

A

Fever, myalgia, headache, CONJUNCTIVAL SUFFUSION +/-rash (red conjunctiva with jaundice eyes, no inflammatory exudate)

24
Q

Treatment of leptospirosis?

A

outpatient = doxycycline, inpatient IV penicillin

25
Q

how do you get brucellosis?

A

exposure to unpatureized cheese, uncooked meat.

26
Q

early symptoms of brucellosis?

A

acute/indolent onset fever, aches, with hepatosplenmoegaly.

27
Q

late symptoms of brucellosis?

A

bone, liver, SACROILLITIS, tendons, CNS

28
Q

Treatment of brucellosis?

A

doxycycline + rifampin or monotherapy strep/gent. Bacrtrim in kids/pregos

29
Q

Lab findings in brucellosis?

A

WBC normal/low, anemia, thrombocytopenia

30
Q

Acute treatment of Q fever?

A

doxycycline or levofloxacin or azithromycin

31
Q

chronic treatment of q fever?

A

doxycycline + hydroxychloroquine

32
Q

how do you get Q fever?

A

inhale spores from farm animals/cats in straw, manure, parturient tissue.

33
Q

symptoms of Q fever?

A

acute pneumonia, chronic endocarditis, granulomatous hepatitis

34
Q

wild game, tick on wild game, squirrles, beavers zoonotic

A

Tularemia

35
Q

eating unpateurized cheese from overseas zoonotic

A

brucellosis

36
Q

handling overseas animal hides/hairs zoonotic

A

anthrax

37
Q

animal urine on intact skin zoonotic

A

leptospirosis

38
Q

culture negative endocarditis in a homeless patient? zoonotic

A

bartonella quintana

39
Q

culture negative endocarditis in patient with animal exposure? zoonotic

A

coxiella burnetti

40
Q

tender lymph node with zoonotic?

A

bartonellosis, tularemia, plague

41
Q

sacroiliits zoonotic association?

A

brucellosis

42
Q

Slaughterhouse, veterinations, cats giving birth zoonotic association?

A

q fever

43
Q

fever and jaundice zoonotic

A

leptospirosis