Zoonoses Flashcards
Tularemia
Rabbits, hot spots “AR, KS, NE, MS, OK”
facultative intracellular tiny, GNCB, francisella tularensis
Pneumonia/cutaneous
Streptomycin/cipro/doxy
Brucellosis
Pig/goat/cattle, abattoir, South and SW
Facultative intracellular GNCB, brucella suis
undulent FUO/bacteremia
doxy + rifampin; neurologic add ceftriaxone
Hantavirus
4-corners region (AZ, NM, CO, UT), deer mice
enveloped ssRNA Bunyaviridae, Sin Nombre virus
pneumonia/HFRS, increase WBC, decrease plt
ribavirin + supportive
Leptospirosis
rodent urine
tightly coiled spirochete
Weil’s, Pul hemorrhage
doxy, pcn, ceftriaxone (severe)
Anthrax
animal hides, rugs
GPB, Bacillus anthracis (medusa head)
pneumonia, cutaneous (black eschar)
doxy, cipro, pcn
Babesiosis
Nantucket, ticks (ixodes)
Apicomplexa infects RBCs, B. microti, B. divergens
fever, hem anemia, decrease plt
atrovaquone + azithromycin
Lyme disease
Deer ticks (ixodes)
weak GN spirochete (lightly coiled)
bullseye rash, arthralgias
doxy, azithro, ceftriaxone (refractile/late)
Yersinia pestis
prairie dogs, fleas
bubo plague, necrotic pneumonia, sepsis
streptomycin, cipro, doxy
Ehrlichosis
Chipmunk/deer, ticks
Anaplastacea
fever, arthralgia, decrease wbc, plt; human monocytic ehrlichosis
doxy/rifampin
Q fever
cattle, sheep, goats
obligate intracellular GNCB
Acute: fever, chills, HA, pneumonia
Chronic:culture-neg endocarditis
doxycycline
Epidemic Typhus (R. prowazekii)
flying squirrels, lice
fever, rash, HA, CNS
doxy/chloramphenicol
RMSF (R. ricketsii)
Ticks
intracellular GNCB
fever, rash, CNS, hemolytic anemia
doxy/chloramphenicol
Rabies
Bats
enveloped ssRNA filovirdae virus (rhabdoviridae, lyssavirus)
encephalitic and paralytic forms, negri bodies postmortem
cleansing, human diploid cell vaccine, human rabies immunoglobluin, fivapiravir
Ebolavirus, Marburgvirus
primates, fruit bats, humans
enveloped ssRNA virus
flu-like, V/D, rash, hemorrhaging, sequelae (arthralgia, myalgia, vision loss)
Zika virus
primates, humans, mosquito
enveloped ssRNA flaviviridae virus
fever, maculopapular rash, HA, joint/muscle pain, conjunctivitis; Guillain-Barre in adults
congenital microcephaly, vision and hearing problems