Zafer

Question 1

Which of the following types of lipids is most increased in hereditary deficiency of the enzyme lipoprotein lipase?
• Phospholipids
• Sphingolipids
• cholesterol esters
• Free fatty acids
• triglycerides

Answer 1

• triglycerides

Question 2

Which of the following enzymes is thought to have decreased activity in a patient with blood chylomicron and VLDL levels above normal?
• Pancreatic Lipase
• Hormone sensitive lipase • Lipoprotein Lipase
• Hepatic Lipase
• Gastric Lipase

Answer 2

• Lipoprotein Lipase

Question 3

Which hyperlipoproteinemia is characterized by glucose intolerance and hyperuricemia, an increase in plasma triglycerides, and develops secondary to diabetes?
• Type I
• Type IIa
• Type III
• Type IV
• Type V

Answer 3

• Type IV

Question 4

What is your diagnosis in a patient with mutation in ATP-dependent cassette carrier-I, recurrent polyneuropathy, lymphadenopathy, orange tonsillar hyperplasia, hepatosplenomegaly and no HDL?
• Wollman’s disease
• Type V hyperlipoproteinemia
• Abetalipoproteinemia
• Tangier’s disease
• Zelweger syndrome

Answer 4

• Tangier’s disease

Question 5

Which enzyme deficiency is most likely in a patient with an increased free cholesterol/Ester cholesterol ratio and a high Lipoprotein X level?
• Lipoprotein Lipase
• Carnitine acyl transferase
• Hormone sensitive lipase
• Lecithin cholesterol acyl transferase (LCAT)
• Hepatic Lipase

Answer 5

• Lecithin cholesterol acyl transferase (LCAT)