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Rabia Flashcards

1
Q

Soru Metni: Concentric laminary fibrous thickening and fibrinoid necrosis, similar to onion membranes on the wall of the kidney arteriols, are monitored in which of the following?

A) Hyalen arteriolocylerosis
B) Mönckeberg’s medial calcific sclerosis
C) Hyperplastic arteriolocyclerosis
D) Renal atherosclerosis
E) Fibromuscular dysplasia

A

C) Hyperplastic arteriolocyclerosis

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2
Q

Soru Metni: Which of the following is not an
example of real aneurysm?
A) Athererosclerotic aortic aneurysms
B) Syphilis aneurysm
C) Congenital vascular aneurysm
D) Postmyocardial left ventricular aneurysms
E) Postmyocardial infarction rote limited to
pericardia

A

E) Postmyocardial infarction rote limited to
pericardia

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3
Q

Soru Metni: In the thoracic aorta, obliterative endarteritis in the vaso vasorum of the adventitia layer, plasma cell inflammation and aneurysms caused by destruction in tunika media are seen in which of the following?

A) Infective endocarditis

B) Tuberculosis

C) Syphilis

D) Salmonella gastroenteritis

E) Brucellosis

A

C) Syphilis

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4
Q

Which of the following is the morphological lesion that causes aortic dissection in Marfan syndrome?

A) Inflamation

B) Atherosclerosis

C) Obliterative endarteritis

D) Cystic medial degeneration

E) Fibrosis

A

D) Cystic medial degeneration

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5
Q

Microscopic examination of the temporal artery biopsy material of a 55-year- old female patient with headache, weakness, weight loss and intermittent temporary vision problems shows granulomatous inflammation consisting of giant cells of langhans type and foreign body type and destruction of internal elastic lamina.

Which of the following is the most likely diagnosis in the patient?

A) Temporal arteritis

B) Poliarteritis nodoza

C) Wegener’s granulomatosis

D) Microscopic PAN

E) Kawasaki disease

A

A) Temporal arteritis

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6
Q

Which of the following is the vasculitis characterized by granulomatous inflammation seen in the small and medium- diameter arteries of the extremities of a middle-aged male patient who smokes?

A) Microscopic PAN

B) Wegener’s granulomatosis

C) Tromboanjitis obliterans

D) Cryoglobulinemic vasculitis

E) Henöch Schönlein purpura

A

C) Tromboanjitis obliterans

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7
Q

Which of the following is the most common small vascular vasculitis in childhood?

A) Kawasaki disease

B) Microscopic PAN

C) Temporal arteritis

D) Henöch Schönlein purpura

E) Churg Strauss syndrome

A

D) Henöch Schönlein purpura

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8
Q

E

A red hemorrhahage lesion is surgically removed from the face of a 17-year- old female patient. Microscopic examination monitors the proliferation of small capillaries separated by a thin stroma, filled with erythrocyte and furnished with endowires. Which of the following is the diagnosis?

A) Cavernous hemangioma

B) Kaposi sarcoma

C) Hemangiopericytoma

D) Capillary hemangioma

E) lymphangionma

A

D) Capillary hemangioma

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9
Q

Which of the following is the painful benign tumor that develops especially from modified straight muscle cells located under the fingernails?

A) Capillary hemangioma

B) Hemangioendothelioma

C) Lymphangioma

D) Glamus tumor

E) Hemangioperieytoma

A

D) Glamus tumor

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10
Q

In myocardial infarction, when to monitor lining loss and pronounced intertical neutrophilic infiltration in muscle cells due to coagulation neerosis in microscopie examination?

A) 2-4 hours

8) 4-12 hours

C) 1-3 days

DJ 3-7 days

E) 7-14 days

A

C) 1-3 days

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11
Q

Which of the following is not one of the major diagnostic criteria for rheumatic fever?

A) Carditis

B) Polyarthritis

C) Erythema marginatum

D) Sydenham chorea

E) Fever (238.5° F)

A

E) Fever (238.5° F)

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12
Q

Which of the following is the valvulite table characterized by small sterile vegetation in the mitral and tricuspid valve in SLE?

A) Acute rheumatic fever

B) Libman-Sacks endocarditis

C) Nonbacterial thrombotic endocarditis

D) Marantic endocarditis

E) Infective endocarditis

A

B) Libman-Sacks endocarditis

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13
Q

Which of the following cardiac tumors consists of large cytoplasm spider cells containing glucogen vacuols?

А) Мухота

B) Papillary fibroelastoma

C) Lipoma

D) Fibroma

E) Rhabdomypma

A

E) Rhabdomypma

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14
Q

)Which disease is PR3 ANCA negative and is related to Hbs

A

polyarthritis

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15
Q

of the following isn’t a vegetative endocarditis

A)Henoch Schonlein pu (Henoch-Schönlein)

B)coxsackie virus A related myocarditis

C) Tromboanjitis obliterans

D) Libman sacks endocarditis

E)non bacterial thrombotic endocarditis

A

B)coxsackie virus A related myocarditis

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16
Q

30)the most malignant tumor of the heart

A)myxoma

B)angiosarcoma

C)fibroma

D)Rhabdomyoma

A

B)angiosarcoma

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17
Q

31)An elder-aged woman presented with a throbbing headache and bilateral tenderness over her forehead. Knobby cords were palpated at the sides and were biopsied. Biopsy shows intimal thickening, granulomatous inflammation centered on the internal elastic lamina, and elastic lamina fragmentation. The most likely diagnosis is

A-) Temporal arteritis

B-) Monckeberg’s arteriosclerosis

C-) Takayasu’s arteritis D-) Kawasaki Disease

E-) Churg-Strauss Syndrome

A

A-) Temporal arteritis

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18
Q

32)malignant tumors marker

A

A)CD31

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19
Q

A Woman came to the ER with nose ache and bleeding…… tested positive for PR3

A

Wegener granulomatosis

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20
Q

of the following yoy won’t find in a person who had myocardial infarction

after 10 days

A)macrophages

B)pronounced neutrophilic infiltration

C)arterial Necrosis

A

B)pronounced neutrophilic infiltration

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21
Q

36)Which isn’t malignant hypertension ?

Hyaline arteriolosvlerosis

A
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22
Q

37) where does the first erosion of a plaque occures

A)Intima

B)Media

C)Lipid layer

A

A)Intima

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23
Q

)of the following isn’t a component of atherosclerosis (plaque)

A)macrophages

B)lipids

C)collagen.

D)eosinophils

E)foam cells

A

D)eosinophils

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24
Q

26-Ateresizklorozda hangisi daha sonra görülür?-migration of smooth muscle cells to the intima layer

A
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25
Q

27-vaka sorusu, 4 yaşında çocuk, cervical LAP oluşumu?

A

Kawasaki disease

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26
Q

28-Which of following is the most malignant heart tumor in adults?

A)myxoma
B)rhabdomysarcoma
C)angiosarcoma
D)metatasis
E)synovial sarcoma

A

D)metatasis

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27
Q

Mitral stenosisin en sık olan sebebi?-

A

chronic rheumatic valva disease

28
Q

30-MI’dan sonra nekroz ne zaman görülür?-4-12 hours

A
29
Q

32)Düz kas hücrelerinden kaynaklanan ağrılı tümör (tırnak altını tutar)?—-

A

glomus tumor

30
Q

30 yaşında erkek hasta.Çok fazla ağrısı var.Damar içinde trombüs yapısı var Küçük arter ve venleri tutan, sinir liflerini tutan vaskülit?

A

thromnoanjitis obliterans

31
Q

Patient who have operated for left breast cancer 10 years ago is admitted with complants of redness and swelling in the left arm. What immunological marker to study on the biopsy gives specific findings absolute nature of the
tumor?

A)LCA
B)vimentin
C)S-100
D)CD 34
E)CD 68

A

D)CD 34

32
Q

40 yaşındaki kadın radial arter nabızsızlık?

A

takayasu arteritis

33
Q

37-Which of following is the most cause of myocarditis?

A)cornyobacterium dipteria

B)CMV

C)HIV

D)coxackie virus

E)trypanosoma cruzi

A

D)coxackie virus

34
Q

Vaka sorusu PR3 anca geçiyor soruda?—–

A

wegener’s granulomatosis

35
Q

Vaka sorusu 65 yaşında temporal artery etkilenmiş granulamotus infection?

A

Large vessels giant cell vasculitis with fragmentation of elastic lamina

36
Q

which one is Most common cause for right heart failured?

A

Left sided heart failure

37
Q

which one is first seen before atherom plaque ?

A

Cevap: A fatty streak

38
Q

Hyperplastic artherolosclerosis için hangisi doğrudur?

A

Cevap: is associated with proggressive hypertansion (diastolic > 120 mmHg)

39
Q

Cevap: Plaque formation of arterial walls triggering the clotting cascad

A
40
Q

Vaka sorusu PR3-ANCA ve MOP-ANCA negatif hepatitis B infections ve her iki böbreği de etkilemiştir tanısı nedir?

A

Cevap: Segmental transmural inflammation with fibrinoid necrosis

41
Q

Hypertension aşağıdakilerden hangisine sebep olmaz?

Cevap: Raynaud Phenomenon

A

Cevap: Raynaud Phenomenon

42
Q

Aşağıdakilerden hangisi “aneurysm in tanımıdır?

is a congenital or acquired weakness of the vessel Wall media, resulting in a localized dilation or outpouching

A

is a congenital or acquired weakness of the vessel Wall media, resulting in a localized dilation or outpouching

43
Q

Aşağıdakilerden hangisi PAN’a eşlik eder?

A

Hepatitis B virus

44
Q

Aşağıdakilerden hangisi bir “right to left shunt” örneğidir?

A

Tetralogy of Fallot

45
Q

Ml sonrası evreler ile ilgili aşağıdakilerden hangisi yanlıştır?

Cevap: Grossly within 18-24 hrs: White/grey firm scar

A
46
Q

Aşağıdakilerden hangisi yanlıştır

Angiosarcomas are the most common tumor of the heart

A
47
Q

Vaka sorusu: 75 yaşında kadın, granulomatous, çene ağrısı, başın çift lateral tarafında gerginlik, görmede bozukluk

A

Giant cell arteritis

48
Q

Vaka sorusu hasta 74 yaşında: Atherosclerosis en-yüksek risk faktörü aşağıdakilerden hangisidir?

A

Cevap: Hyperlipidemia

49
Q

Ischemiden ilk etkilenen bölge aşağıdakilerden hangisidir?

Cevap: a small zone of the myocardium beneath the endocardial surface

A
50
Q

ANCA pozitif vaskulitler aşağıdakilerden hangisinde verilmiştir?

A

Cevap: Granulomatosis with Polyangitis, Churg-Strauss Sydrome, and microscopic polyangitis

51
Q

Which one of the following is not the component of atherosclerotic plaque?

A-) Foamy macrophages

B-) Cholesterol crystals

C-) Extracellular matrix and smooth muscle cells

D-) T cells

E-) B cells

A

E-) B cells

52
Q

All of the following statements about cardiomyopathies are correct, except?

A-) Cardiomyopathies are a group of diseases that affect the heart muscle B-) In hypertrophic cardiomyopathy the heart muscle enlarges and thickens

C-) In dilated cardiomyopathy the ventricles enlarge and weaken

D-) In restrictive cardiomyopathy the ventricle stiffens.

E-) Hypertrophic cardiomyopathy may be caused by amyloidosis, hemochromatosis and some cancer treatments

A

E-) Hypertrophic cardiomyopathy may be caused by amyloidosis, hemochromatosis and some cancer treatments

53
Q

An elderly men from the Mediterranean region,presenting with erythematous or violaceous patches on the lower extremities. A tissue biopsy shows spindle cells forming slits containing red blood cells. Mitotic activity is moderate and pleomorphism is minimal. The tumor is highly vascular, containing abnormally dense and irregular blood vessels, which leak red blood cells into the surrounding tissue. Spindle cells are positive for CD31 and HHV8. The most likely diagnosis is

A-) Hemangiopericytoma

B-) Bacillary angiomatosis

C-) Arteriovenous malformation

D-) Kaposi’s sarcoma

E-) Hemangioma

A

D-) Kaposi’s sarcoma

54
Q

Aschoff bodies are pathognomonic for

A-) Rheumatic fever

B-) Infective endocarditis

C-) Thrombotic endocarditis

D-) Carcinoid heart disease

E-) Libman-Sacks Disease

A

A-) Rheumatic fever

55
Q

Ezber
Serous complications in a patient who has just suffered an acute myocardial infarction Include all of the following except

A-) Cardiac tamponade B-) Peripheral embolism

C-) Mitral valve incompetence

D-) Aortic aneurysm

E-) Rupture of the ventricular septum

A

D-) Aortic aneurysm

56
Q

An elder-aged woman presented with a throbbing headache and bilateral tenderness over her forehead. Knobby cords were palpated at the sides and were biopsied. Biopsy shows intimal thickening, granulomatous inflammation centered on the internal elastic lamina, and elastic lamina fragmentation. The most likely diagnosis is

A-) Temporal arteritis

B-) Mönckeberg’s arteriosclerosis

C-) Takayasu’s arteritis

D-) Kawasaki Disease

E-) Churg-Strauss Syndrome

A

A-) Temporal arteritis

57
Q

A 62-year-old man experiences crushing substernal chest pain. After 4 days of circulatory support in the intensive care unit, he dies. Histologic study of his heart would show all of the following findings except?

A-) Coagulative necrosis

B-) Liquefactive necrosis

C-) Hypereosinophilic wavy fibers

D-) Neutrophilic infiltrate

E-) Early phagocytosis of dead cells

A

B-) Liquefactive necrosis

58
Q

All of the following statements about cardiac tumors are correct, except? A-) Myxomas are the most common primary tumor of the adult heart

B-) Myxomas may be a component of Carney complex C-) Rhabdomyomas are the most common primary tumor of the pediatric heart

D-) Rhabdomyomas are associated with tuberous sclerosis

E-) Angiosarcomas are the most common tumor of the heart

A

E-) Angiosarcomas are the most common tumor of the heart

59
Q

All of the following congenital heart diseases causing a left-to-right shunt,

except?

A-) Atrial septal defect

B-) Ventricular septal defect

C-) Patent ductus arteriosus

D-) Patent foramen ovale

E-) Transposition of the great arteries

A

E-) Transposition of the great arteries

60
Q

Hypertensive heart disease induce

A-) Myocyte hypertrophy

B-) Myocyte hyperplasia

C-) Myocyte atrophy

D-) Myocyte hypoplasia

E-) Myocyte aplasia

A

A-) Myocyte hypertrophy

61
Q

Which one of the following is the major risk factor for the development of Buerger Disease?

A-) smoking

B-) PR3-ANCA

C-) MPO-ANCA

D-) Exposure to irritant gases

E-) Intravenous drug abuse

A

A-) smoking

62
Q

In the HE evaluation of a 44-year-old male kidney biopsy, the Bowman’s spaces of the glomerular structurenare observed to be closed .In the detailed evaluation. the cause of the event is determined to be the proliferation of the parietal celss .What should be the definition of the glomerular pathology?
A)Crescentic glomerulonephritis B)Membranoproliferative glomerulonephritis type 1
C) Acute tubular necrosis
D) Hydronephrosis

A

A)Crescentic glomerulonephritis

63
Q

what is the first stage in developing atherosclerosis plaque ? A)Foam cells formation
B)Accumulation of lipids
C)Chronic endothelial injury

A

C)Chronic endothelial injury

64
Q

which of the following is most common cause of mitral valve stenosis?
A) infectious endocarditis
B) acute rheumatic fever disease
C) hypertension
D) chronic rheumatic valve disease
E) chronic heart failure

A

D) chronic rheumatic valve disease

65
Q

A 30-year-old woman has smoked one pack of cigarettes per day since she was a teenager. She has had painful
thromboses of the superficial veins of the lower legs for 1 month and episodes during which her fingers become blue and
cold. Over the next year, she develops chronic, poorly healing ulcerations of her feet. One toe becomes gangrenous and
is amputated. Histologically, at the resection margin, there is an acute and chronic vasculitis involving medium-sized
arteries, with segmental involvement. Which of the following is the most appropriate next step in treating this patient?
A)Aortic dissection
B) Kawasaki disease
C) Microscopic polyangiitis
D) Takayasu arteritis
E) Tertiary syphilis
F) Thromboanjitis obliterans

A

F) Thromboanjitis obliterans F) Thromboanjitis obliterans

66
Q

Which of the following is the most common primary malignant heart tumor in adults?
a) Rhabdomyosarcoma
b) Myxoma
c) Lipoma
d) Rhabdomyoma
e) Synovial sarcoma

A

a) Rhabdomyosarcoma

67
Q

57- Serous complications in a patient who has just suffered an acute myocardial infarction. Include all of the following except?
a) Cardiac tamponade
b) Peripheral embolism
c) Mitral valve incompetention
d) Aortic aneurysm
e) Rupture of the ventricular septum

A

d) Aortic aneurysm

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