Kızıltunç

Question 1

Hypoxia inducible factor alpha and hypoxia inducible factor beta are combine in the nucleus:

During the decreased NADH level

During the active prolyl hydroxylase

During the increased proteasome activity

During the increased hydroxylation reactionel

During the decreased oxygen concentration

Answer 1

During the decreased oxygen concentration

Question 2

Where is respiratory chain located?

A) inner endoplasmic reticulum

B) inner cell membrane

C) inner lysosome membrane

D) in membrane space

E) inner mitochondrial membrane

Answer 2

E) inner mitochondrial membrane

Question 3

Which is inhibited by oligomycin?

A) ATP synthesis

B) cyt P450

C) complex III

D) complex II

E) cytochrome oxidase

Answer 3

A) ATP synthesis

Question 4

All of them are required for detoxification of the superoxide radical in the mitochondrial matrix. except:

a) Glutathione reductase

b) Superoxide dismutase

c) Myeloperoxidase

d) Glutathione peroxidase

e) Glutathione

Answer 4

c) Myeloperoxidase

Question 5

which molecule in hpoxia?

Answer 5

• lactate

Question 6

Which is a recrabrase antioxidant?
A)vit- E
B) Vit A
C) Vit-C
D)vit B12
E) VitB6

Answer 6

A)vit- E

Question 7

Complex Ill is inhibited by
A) azido
B)cyanide
C)carbon monoxide
D) antimycin A
E) rotenone

Answer 7

D) antimycin A

Question 8

The……….. is not a free radical.
A) superoxide anion
B)singlet oxygen
C) hydroxyl ion
D) peroxyninte
E) hydrogen peroxide

Answer 8

C) hydroxyl ion

Question 9

………… has not any function in generation and release of ROS during phagocytosis.
A) Superoxidase
B) Chloride ion
C) Lysosomes
D) Glutathione peroxidase
E) Myeloperoxidase

Answer 9

D) Glutathione peroxidase

Question 10

………… have bactericidal activity in
macrophages.
A) Tocopherol and vit-A
B) Chloride and iron
C) NADPH and NADP+
D) H202 and HOCI
E) Oxygen and ascorbate

Answer 10

D) H202 and HOCI

Question 11

Which term is true for the dinitrophenol?

A) shuttle protein
B) biradical molecule
C) drugs.
D) uncoupler
E) high energy compound

Answer 11

D) uncoupler

Question 12

Which one is the small antioxidant peptide?

Al Albumin
B) Carosne
C)hemopexin
D) SOD
E) Glutathione

Answer 12

E) Glutathione

Question 13

oxidative stress is decreased by……..
A) -polyol pathway
B) glycation
C) -NADPH onidase
D) drugs
E) uric acid

Answer 13

E) uric acid

Question 14

Statement: ………….. is synthesised by lipid peroxidation

A) alcohol
B) homocysteine
C) hemoglobin
D) glucose
E) malondialdahide

Answer 14

E) malondialdahide

Question 15

oxidative stress is increased by……..

A) glutathione
B)-hemopexin
c) typerbaric oxygen
D) -ferritin
E) carosine

Answer 15

c) typerbaric oxygen

Question 16

Longevity is extended by…….

Answer 16

Calori restruction

Question 17

Which of the tollowing mechanism is tie 1
dinitrophenol function in OXP?
A) actvating the H.ATPase
B) actvating coenzyme Q
C) allowing for proton exchange across The inner mitochondrial membrane
D) blocking proton transport across the inner
mitochondrial membrane
E) enhancing orygen transport across the inner
mitochondrial membrana

Answer 17

C) allowing for proton exchange across The inner mitochondrial membrane