Yumori Dry Eye Flashcards
What is Sjogren syndrome?
autoimmune disorder chrcteried by lymphocytic inflammation & destruction of lacrimal & salivry glands / exocrine organs
affects the whole body
stiffness of joins in the early morning
worse later in the day
usually bilateral
Wht is the SS triad?
dry eyes
dry mouth
parotid gland enlargement
Primary SS
when it exists in isolation
affects females more than males
Secondary SS
when it exists with another disease ; primarily lupus or rheumatoid arthritis
acs SS specifications
Positivityforanti-SSAoranti-SSBantibodies,orpositive rheumatoid factor together with significantly positive antinuclear antibody.
• Ocularsurfacestainingaboveacertaingrade.
• Focallymphocyticsialadenitistoaspecifiedextenton
salivary gland biopsy
Symptoms of dry eye
grittness dryness blurriness stringy dischrge transient blurring of vision redness / crusting of the lids symptoms of KCS when reduced blinking increased osmolarity (salty) & inflammtion tear film instability
Signs in meibomin glnds
Posterior bleph.
Signs Conjuctiva
redness
sting with fluorescein
keratenition
conjuctivachalasis
Types of Dry eye?
aueous deficient
evaporative
Evaporative causes
intrinsic (meibomian glnd disorder. ectropian, lagopthalmos, doesn’t blink freuently; systemic medication (acutane) )
extrinsic (vit. a def. , topical drug preservatives, contct lenses, Ocular surface diseases , allergies)
aueous def.
Sjorgen
Major long term SS
lymphoma
Lifetime risk NHL: 5%
– 16-44 times higher than normal population
Medications cause DED
antihist amine
antidepressants
Cut off for tear lab
308 ; greter thn 8 difference
Level one
eduction
envronmentl chnges
eye lid therapies (lid hygiene )
