Yr 3 Formative Qs Flashcards
Why wouldn’t you measure serum growth hormone levels for acromegaly?
GH released in pulsatile manner as it has short half life and varies beteween time of day & gender
Insulin stress test- gives hypo and causes a release of stress hormones: should see an increase if working.
Gold standard for testing pituitary
Most common reason for this is post-transphenoidal surgery
Reassurance - transient hyperthyroidism occurs in early pregnancy that will go back to normal
PTU
Describe the dosing differences between initiating hyperthyroidism in pregnant and non-pregnant people [2]
In pregnancy
- start with low dose PTU and titrate up to control T4 levels
In non-pregnant
- start with high dose carbimazole and titrate down
Which thyroid manifestation of hyperthyroidism is a contraindication for radioactive iodine treatment? [1]
Contraindicated if have thyroid eye disease
(so go on anti-thyroid treatment for a year before)
Give IV bisphosphinates
What Ca2+ requires urgent treatment? [1]
> 3.5 mmol
1. Parathyroid adenoma
4. Sarcoidosis
Describe how you work out if high Ca2+ is from primary, secondary or tertiary hyperparathyroidsim [3]
Needle decompression in 2nd IC space