MET3 Revision: Colorectal Surgery I Flashcards

1
Q
A
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2
Q

How would Meckel’s diverticulitis present? [5]

A
  • most common: painless rectal bleeding
  • age < 2 years
  • passage of bright red blood per rectum (haematochezia)
  • intractable constipation (obstipation)
  • It is clinically indistinguishable from appendicitis: Right sided pain
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3
Q

Describe the pathophysiology of Meckel’s diverticulum

A

Meckel’s diverticulum is a small outpouching extending from the wall of the intestine and located in the lower portion of the small intestine.

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4
Q

Name 4 causes of bleeding that may cause acute abdominal pain [4]

A

Bleeding:
- AAA
- Ulcer
- Ectopic
- Trauma

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5
Q

Imaging used to investigate acute abdominal pain [3]

A

Plain radiographs (clinical effectiveness is queried)
- Erect chest XR: pneumonia
- Supine abdomen XR: small bowel obstruction

CT (investigation of choice)

Ultrasound
- Highly sensitive & first line for biliary pathology
- Good for gynaecological
- Bad for appendicitis

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6
Q

You suspect a patient has a biliary pathology, what is the first line of imaging used to diagnose this? [1]

A

Ultrasound

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7
Q

What is ascending cholangitis? [1]
What is it most commonly caused by? [1]
What is a classic triad of symptoms? [3]

A

Ascending cholangitis:
- is a bacterial infection of the biliary tree
- common predisposing factor is gallstones
- Charcots triad: RUQ; fever & jaundice

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8
Q

Describe the character of the pain described in a inflammation [1]

A

Constant dull pain: think appendicitis, diverticulitis

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9
Q

Describe the character of the pain described in peritonitis [1]

A

Constant sharp pain

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10
Q

Bowel sounds are helpful in suspected obstruction. Describe how this can be helpful [2]

A

High pitched (tinkling): obstruction

Absent: ileus (non-mechanical obstruction)

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11
Q

Describe a way of classifying bowel obstructions [3]
Name three suggestions for the each of the above [9]

A

Extramural: block bowel from outside
- Adhesions (congenital or aquired)
- Hernia
- Volvulus (caecal; sigmoid; small bowel)
- Compression from lymph nodes

Intramural: blockage from within the wall
- Tumours (adenocarcinoma, GISTs, lymphoma, leiomyosarcoma)
- Strictures bowel has narrowed due to: diverticular, ischaemic, IBD, post op,
- Intussusecption (wall of bowel moves into itself & blocks itself, most commonly at terminal ileum and caecum)

Intraluminal: within the wall
- Gall stones
- Bezoar
- Foreign body
- Meconium

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12
Q

What is the imaging that is the investigation of choice for bowel obstruction? [1]
State other imaging used [1]

A

CT: imaging of choice;
XR

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13
Q

What is gastrograffin AXR? [1]
When is its use indicated? [1]

A

Gastrograffin:
* Water soluble contrast for small bowel adhesive obstruction.
* If gastrograffin has passed into colon then suggests that will resolve (if not then surgery is indicated)

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14
Q

The “big three” causes account for around 90% of cases of bowel obstruction.

What are they? [3]
Where are they found (small or large bowel) [3]

A

Adhesions: small bowel
Hernias: small bowel
Malignancy: large bowel

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15
Q

Describe the pathophysiology of small bowel obstruction [5]

A
  • Passage of food, fluids and gas, through the intestines becomes blocked
  • Obstruction results in a build up of gas and faecal matter proximal to the obstruction
  • This causes back-pressure: resulting in vomiting and dilatation of the intestines proximal to the obstruction.
  • When there is an obstruction, and fluid cannot reach the colon, it cannot be reabsorbed: as a result, there is fluid loss from the intravascular space into the gastrointestinal tract leading to hypovolaemia & shock
  • The higher up the intestine the obstruction, the greater the fluid losses as there is less bowel over which the fluid can be reabsorbed.
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16
Q

How does bowel obstruction lead to bowel ischaemia, infarction, necrosis, and perforation? [3]

A
  • With time, bowel wall oedema forms
  • This compresses the intestinal veins and lymphatics, reducing the venous drainage of the bowel
  • As this occurs, it compresses intestinal arterioles and capillaries
  • This prevents arterial perfusion to the bowel wall.
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17
Q

What’s a pneumonic for remembering the causes of small bowel obstruction?

A

HANG IVs”

Hernias 2%
Adhesions (from previous surgery with formation of intra abdominal adhesions, commonly colorectal and gynaecological surgery)
Neoplasms (malignant, benign, primary or secondary) (5%)
Gallstone ileus
Intussusception
Volvulus
Strictures (eg Crohn’s disease (6%), ischaemia)

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18
Q

State 4 causes of intestinal adhesions that could contribute to the formation of bowel obstruction [4]

A

Abdominal or pelvic surgery (particularly open surgery)
Peritonitis
Abdominal or pelvic infections (e.g., pelvic inflammatory disease)
Endometriosis

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19
Q

Describe the difference in presentation of more proximal and more distal bowel obstructions [2]

A

In more proximal bowel obstructions:
- patients tend to present earlier
- abdominal pain and vomiting are the predominant symptoms.

In distal small bowel obstructions:
patients usually present after 2-3 days of abdominal pain.
- The predominant symptoms are abdominal distension and constipation.

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20
Q

Describe the relationship between abdominal pain and vomiting in SBO? [1]

A
  • Abdominal pain often precedes vomiting (constant pain may indicate bowel ischaemia)
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21
Q

Describe the nature of vomit of SBO [1]

A

green bilious vomiting

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22
Q

Explain what VBG readings would you suspect with a patient with bowel obstruction? [2]

A

Metabolic alkalosis due to vomiting stomach acid

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23
Q

Describe the non-operative treatment for SBO [3]

A

Drip and Suck:

  • Nil by mouth
  • IV fluids to hydrate the patient and correct electrolyte imbalances
  • NG tube with free drainage to allow stomach contents to freely drain and reduce the risk of vomiting and aspiration
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24
Q

What are the indications for surgery for SBO? [2]

A

Bowel compromise (e.g. ischaemia, perforation, necrosis), generally occurring in complete bowel obstructions

Surgically correctable causes (e.g. volvulus, incarcerated hernia, gallstone ileus, foreign body ingestion, tumour)

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25
Q

How would you surgically treat SBO? [4]

A
  • Exploratory surgery in patients with an unclear underlying cause
  • Adhesiolysis to treat adhesions
  • Hernia repair
  • Emergency resection of the obstructing tumour
  • If surgery is being undertaken, patients should have antibiotic prophylaxis
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26
Q

What are 4 key emergency risks of SBO? [4]

A

Hypovolaemic shock due to fluid stuck in the bowel rather than the intravascular space (third-spacing)
Bowel ischaemia
Bowel perforation
Sepsis

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27
Q

If surgery is indicated for SBO, patients should be given antibiotic prophylaxis of which antibiotics? [3]

A

cefoxitin, or ampicillin plus gentamicin

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28
Q

What is A?

Anal abscess
Anal fissure
Haemorrhoid
Anal fistula

A

What is A?

Anal abscess
Anal fissure
Haemorrhoid
Anal fistula

An anal fissure is a superficial tear in the skin distal to the dentate line

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29
Q

What does this image depict?

Anal abscess
Anal fissure
Haemorrhoid
Anal fistula

A

What does this image depict?

Anal abscess
Anal fissure
Haemorrhoid
Anal fistula

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30
Q

What does the following best describe?

abnormal tunnel under the skin that connects the anal canal in the colon to the skin of the buttocks

Anal abscess
Anal fissure
Haemorrhoid
Anal fistula

A

What does the following best describe?

abnormal tunnel under the skin that connects the anal canal in the colon to the skin of the buttocks

Anal abscess
Anal fissure
Haemorrhoid
Anal fistula

31
Q

What FBC / blood film finding would indicate acute diverticulitis? [1]

A

Polymorphonuclear leukocytosis

BMJ BP: First line invest.

32
Q

Define what is meant by an anal fissure [1]

A

Anal fissure is a split in the skin of the distal anal canal characterised by pain on defecation and rectal bleeding.

They are longitudinal or elliptical tears of the squamous lining of the distal anal canal

33
Q

What makes an anal fissure acute or chronic? [1]

A

Acute: less than 6 weeks
Chronic: more than 6 weeks

34
Q

What are risk factors for anal fissures? [5]

A

constipation
inflammatory bowel disease
sexually transmitted infections e.g. HIV, syphilis, herpes
pregnancy
opiate analgesia

35
Q

Describe the treatment algorithm for acute fissures

A

1st line: soften stool
- high fibre intak
- Bulk forming laxatives
- lubricants like petroleum jelly

2nd line:
- Glyceryl trinitrate

3rd line:
- topical diltiazem (if headaches from glyceryl trinitrate are too much)

36
Q

Why might glyceral trinitrate cause headaches? [1]

A

Some patients experience a headache due to glyceryl trinitrate entering the bloodstream and causing cerebral vasodilatation

37
Q

Describe the treatment algorithm for chronic anal fissures [3]

A

topical glyceryl trinitrate (GTN) is first-line treatment for a chronic anal fissure

Botulinum toxin or sphincterotomy is used after failure of topical treatment for 8 weeks

sphincterotomy:
The operation usually takes about 15 minutes. Your surgeon will make a small cut on the skin near your back passage. They will cut the lower part of the internal sphincter muscle. This will relieve the spasm in the sphincter, allowing a better blood supply to heal the fissure.

38
Q

almost all diverticula are found in the []

A

almost all diverticula are found in the sigmoid colon

39
Q

How does acute diverticulitis present? [5]

A

Severe abdo pain in LLQ
N&V
Constipation (more common than diarrhoea)
Urinary frequency & urgency
PR bleeding

40
Q

How do you determine diverticultis vs UC?

A

UC:
- Bloody diarrhoea

Diverticultis:
- Fever
- Constipation
- LLQ pain

41
Q

Describe two symptoms of complications of diverticulitis [2]

A

pneumaturia or faecaluria may suggest a colovesical fistula
vaginal passage of faeces or flatus may suggest a colovaginal fistula

42
Q

Which investigation method should be avoided in diverticulosis and why? [2]

A

Colonoscopy: should be avoided initially due to the increased risk of perforation in diverticulitis

43
Q

What might an AXR show in diverticulosis? [3]

A

AXR: may show dilated bowel loops, obstruction or abscesses

44
Q

Describe the treatment regime for diverticulitis? [4]

A

mild cases of acute diverticulitis may be managed with oral antibiotics, liquid diet and analgesia CKS

dicycloverine: antispasmodic

if the symptoms don’t settle within 72 hours, or the patient initially presents with more severe symptoms, the patient should be admitted to hospital for IV antibiotics

Consider open or laparoscopic resection for patients who have recovered from complicated acute diverticulitis but have continuing symptoms (such as stricture or fistula)

45
Q

What is a thrombosed haemorrhoid? [1]

How do you determine if an anal presentation is a thrombosed haemorrhoid? [3]

A

Thrombosed haemorrhoids occur when either an internal or external hemorrhoid fills with blood clots.

Thrombosed haemorrhoids are characterised by anorectal pain and a tender lump on the anal margin. It does not normally present with bleeding but this can occur if the haematoma spontaneously bursts.

46
Q

An anal longintudinal tear and fresh rectal bleeding is the diagnosis of? [1]

A

Anal fissure

47
Q

Name a therapeutic drug that is protective for colorectal cancer [1]

A

Aspirin

48
Q

Describe the clincical presentation of colorectal cancer [5]

A

Change in bowel habits:
- Constipation
- Diarrhoea
- Constipation & Diarrhoea alternating
- Frequency
- Tenesmus

PR Bleeding (melena or bright red)

Abdominal pain
- tumour obstructing bowel

Unexplained weight loss

Anaemia:
- Chronic bleeding from tumour

49
Q

What are the three type of colon cancer? [3]

A

Sporadic (95%)
Hereditary non-polyposis colorectal carcinoma (5%)
Familial adenomatous polyposis (<1%)

50
Q

Describe the genetic influence of developing colorectal cancer [2]

A

Hereditary non-polyposis colorectal carcinoma (aka Lynch syndrome; HNPCC, 5%):
- Autosomal dominant
- DNA mismatch repair, effecting MSH2, MLH1, MHSH6, PMS2 genes
- Does not cause adenomas
- Tumours develop in isolation

Familiar adenomatous polyposis (FAP):
- autosomal dominant
- malfunction of tumour suppressor gene adenomatous polyposis coli (APC)
- causes many polyps in the large intestine

51
Q

What is the investigation of choice for colorectal cancer? [1]
State three other investigations [3]

A

Colonoscopy:
- can biopsy
Sigmoidscopy
CT colonography
Staging CT: looks for metastasis of other cancers (CT thorax, abdomen, pelvis)

52
Q

Describe typical features of colorectal in colonscopy [2]

A

Shouldering
Mucosal obstruction

53
Q

What is the name for the staging criteria of colorectal cancer? [1]
Describe each stage [4]

A

Duke’s classification

54
Q

Describe how colorectal tumours can present via colonoscopy [3]

A

Ulcerating
Stenosing
Polypoidal

55
Q

What does this colonoscopy of colorectal cancer depict?

Ulcerating
Stenosing
Polypoidal

A

Ulcerating
Stenosing
Polypoidal

56
Q

What does this colonoscopy of colorectal cancer depict?

Ulcerating
Stenosing
Polypoidal

A

What does this colonoscopy of colorectal cancer depict?

Ulcerating
Stenosing
Polypoidal

57
Q

What does this colonoscopy of colorectal cancer depict?

Ulcerating
Stenosing
Polypoidal

A

What does this colonoscopy of colorectal cancer depict?

Ulcerating
Stenosing
Polypoidal

58
Q

Options for managing bowel cancer (in any combination) are? [4]

A

Surgical resection
Chemotherapy
Radiotherapy
Palliative care

59
Q

Describe how surgical resection of colorectal cancer occurs [4]

A
  • Laparoscopic or robotic surgery
  • Resection of tumour
  • Most tumours are tailored around the resection of particular lymphatic chains
  • Anastamose remaining remaining bowel OR stoma
60
Q

Describe the different types of colorectal cancer surgery that are used, depending on the location of the cancer [6]

A

Right hemicolectomy:
- involves removal of the caecum, ascending and proximal transverse colon.

Left hemicolectomy:
- involves removal of the distal transverse and descending colon.

High anterior resection:
- involves removing the sigmoid colon (may be called a sigmoid colectomy).

Low anterior resection:
- involves removing the sigmoid colon and upper rectum but sparing the lower rectum and anus.

Abdomino-perineal resection (APR):
- involves removing the rectum and anus (plus or minus the sigmoid colon) and suturing over the anus. It leaves the patient with a permanent colostomy.

Hartmann’s procedure:
- is usually an emergency procedure that involves the removal of the rectosigmoid colon and creation of an colostomy. The rectal stump is sutured closed. The colostomy may be permanent or reversed at a later date. Common indications are acute obstruction by a tumour, or significant diverticular disease.

61
Q

make sure you know about blood supply for colon bits (its different)

A
62
Q

All patients with newly diagnosed colorectal cancer should have which tests for staging? [3]

A

Entire colon evaluated with colonscopy or CT colonography

Carcinoembryonic antigen (CEA)

CT of the chest, abdomen and pelvis

63
Q

Name the surgical procedure is used for obstructed right sided tumours cancer? [1]

Name and describe the surgical procedure is used for obstructed rectosigmoidal cancer? [2]

A

Right hemicolectomy

Hartmann’s procedure:
- remove recosigmoidal colon & rectal stump suture closed (permenantly or reversed)
- create colostomy

64
Q

Describe the adjuvant chemotherapy given for colorectal cancer: [2]

Describe the biologicals used [3]

A

Dukes B if poor prognositic factors

Dukes C:
- Fluorouracil (5-FU)
- Capecitabine (first line)

Biologicals:
- Cetuximab (anti-EGFR)
- Panitumubab (anti-EGFR)
- Bevacizumab (anti-VEGF)

65
Q

Radiotherapy is used for pre-op. treatment of which specific type of colorectal cancer? [1]

A

Rectal cancer

66
Q

State 4 reasons why get referred to the two week cancer pathway for colorectal cancers [5]

A

Positive FIT test
Over 40 years with abdominal pain and unexplained weight loss
Over 50 years with unexplained rectal bleeding
Over 60 years with a change in bowel habit or iron deficiency anaemia
Any age with rectal or abdominal mass

67
Q

What type of treatment is radiotherapy generally used for in colorectal cancer? [2]

A

Palliative care
Rectal cancers with high risk of local reoccurence

68
Q

What is the FOLFOX regime of treating colorectal cancer? [3]

A

Chemotherapy regime of:
* 5-FU
* Folinic acid
* Oxaliplatin

69
Q

Question 8 of 113
A 67-year-old man presents to clinic with a history of blood in the stools and weight loss. He was referred for an urgent colonoscopy, which showed a mass in the distal transverse colon. Biopsy confirmed adenocarcinoma. Further investigation reveals no lymph node involvement or distant metastasis.

What surgery should be offered?

Hartmann’s procedure
High anterior resection
Left hemicolectomy
Right hemicolectomy
Total colectomy

A

Question 8 of 113
A 67-year-old man presents to clinic with a history of blood in the stools and weight loss. He was referred for an urgent colonoscopy, which showed a mass in the distal transverse colon. Biopsy confirmed adenocarcinoma. Further investigation reveals no lymph node involvement or distant metastasis.

What surgery should be offered?

Hartmann’s procedure
High anterior resection
Left hemicolectomy
Right hemicolectomy
Total colectomy

70
Q

A 78-year-old man presents to the emergency department with intense abdominal pain. He has not passed faeces or wind in the last 48 hours. When asked, he mentions that he has lost some weight recently and in the weeks preceding this event he has been feeling constipated. The team suspects a large bowel obstruction due to cancer and orders a CT scan, that shows a mass in the hepatic flexure.

Which one of the following surgical management plans is the most appropriate for the patient?

Hartmann’s procedure
High anterior resection
Left hemicolectomy
Low anterior resection
Right hemicolectomy

A

A 78-year-old man presents to the emergency department with intense abdominal pain. He has not passed faeces or wind in the last 48 hours. When asked, he mentions that he has lost some weight recently and in the weeks preceding this event he has been feeling constipated. The team suspects a large bowel obstruction due to cancer and orders a CT scan, that shows a mass in the hepatic flexure.

Which one of the following surgical management plans is the most appropriate for the patient?

Hartmann’s procedure
High anterior resection
Left hemicolectomy
Low anterior resection
Right hemicolectomy

71
Q

Which of the following involves removal of the distal transverse and descending colon?

Hartmann’s procedure
High anterior resection
Left hemicolectomy
Low anterior resection
Right hemicolectomy

A

Which of the following involves removal of the distal transverse and descending colon?

Hartmann’s procedure
High anterior resection
Left hemicolectomy
Low anterior resection
Right hemicolectomy

72
Q

Which of the following involves removing the sigmoid colon and upper rectum but sparing the lower rectum and anus?

Hartmann’s procedure
High anterior resection
Left hemicolectomy
Low anterior resection
Right hemicolectomy

A

Which of the following involves removing the sigmoid colon and upper rectum but sparing the lower rectum and anus?

Hartmann’s procedure
High anterior resection
Left hemicolectomy
Low anterior resection
Right hemicolectomy

73
Q

Which of the following involves removing the sigmoid colon?

Hartmann’s procedure
High anterior resection
Left hemicolectomy
Low anterior resection
Right hemicolectomy

A

Which of the following involves removing the sigmoid colon?

Hartmann’s procedure
High anterior resection
Left hemicolectomy
Low anterior resection
Right hemicolectomy