year 5 Drug list

Question 1

Donepezil

Answer 1

ACHe inhibtor, alzheimer + lewy body dementia

Question 2

galantamine

Answer 2

ACHe inhibtor, alzheimer + lewy body dementia

Question 3

rivastigmine

Answer 3

ACHe inhibtor, alzheimer + lewy body dementia

Question 4

anti psychotic used for delirium?

Answer 4

Haloperidol- 1st line
risperidone
have low anti cholinergic effect

Question 5

Ritalin(Methylphenidate)

Answer 5

ADHD stimulant

Question 6

ADHD non stimulant drug

Answer 6

Atomoxetine

Question 7

What are the side effects of ACHe?

Answer 7

GI upset
headaches
agitation
bradycardia

Question 8

Memantine

Answer 8

non competitive glutamate receptor antagonist, for severe dementia or moderate if intolerance to ACHe inhibitors

Question 9

lisdexamphetamine

Answer 9

adult ADHD stimulant drug

Question 10

GDS?

Answer 10

gereatric depression scale

Question 11

ACE?

Answer 11

adenbrook’s cognitive examination

Question 12

First line SSRI for older adults?

Answer 12

mirtazapine, sertraline

Question 13

medication for bipolar depression?

Answer 13

Quietiapine, lamotrigine

Question 14

Antipsychotics for older adult schrizophrenia?

Answer 14

Amisulpride, olanzapine, risperidone

Question 15

Examples of TCAs,
C
A
I

Answer 15

Clomipramine
Amitryptilline
Imipramine

Question 16

MAOi example

Answer 16

seligine

Question 17

What reaction can occur with seligine?

Answer 17

cheese reaction- high tyramine

Question 18

Risperidone in depot form name?

Answer 18

Paliperidol

Question 19

Examples of extrapyrimidal side effect?BOAT

Answer 19

Bradykinesia
Oculogyric crisis
Akathasia
Tardive dyskinesia

Question 20

Management of oculogyric crisis?

Answer 20

IM procyclidine 5mg- hard to take oral in this state

Question 21

what is a classic feature of serotonin syndrome comapared to NMS?

Answer 21

Myoclonus

Question 22

what are the features of NMS?

Answer 22

CK>1000
lecucytosis
high fever
muscle rigidity
palpitations

Question 23

what is the antidote of diazepam and benzodiazepine?

Answer 23

flumazenil

Question 24

therapeutic range of lithium?

Answer 24

0.4-1

Question 25

what needs to be monitored on lithium? BEETL

Answer 25

``` (BMI eGFR Electrolytes Thyroid )- every 6 months lithium level every 3 months ```

Question 26

If a patient with delirium tries to leave the ward, what should be filled out?

Answer 26

deprivation of liberty safegaurding form under MCA

Question 27

Which physical health can be treated under mental health act?

Answer 27

severe malnutriotion due to eating disorder

Question 28

treatment for methanol poisoning?

Answer 28

fomepizole | ethanol

Question 29

SSRI side effects? GASSd

Answer 29

Early: GI symptoms, anxiety, sleep disturbance (GASSd) ongoing: sexual dysfunction

Question 30

Define perintal period?

Answer 30

pregnancy + 1 year after

Question 31

Scale for postnatal depression?

Answer 31

Edinbrugh postnatal depression scale

Question 32

safe SSRI for breastfeeding

Answer 32

setraline and paroxetine

Question 33

contraindicated SSRI for breastfeeding?

Answer 33

fluoxetine- long half life

Question 34

which anti emetic increases breast milk production?

Answer 34

metaclopramide

Question 35

SSRI contraindicated in pregnancy?

Answer 35

paroxetine

Question 36

What congenital abnormality is benzodiazepine associated with?

Answer 36

Cleft lip

Question 37

Most common side effect of lithium?

Answer 37

Tremor Polydypsia Polyuria Weight gain

Question 38

Criteria for agoraphobia?

Answer 38

``` anxiety due to 2 out of: crowds public places travelling alone travelling away from home ```

Question 39

what substance might people with social phobia abuse?

Answer 39

alcohol

Question 40

management of phobias?

Answer 40

CBT 12 weeks with exposure therapy + breathing technique and other relaxation methods Beta blockers SSRI/SNRI

Question 41

define panic disorder

Answer 41

intermittent anxiety not triggered by a specific stimulus

Question 42

Investigation in panic disorder

Answer 42

alcohol withdrawal? TFT Urine drug screen ECG

Question 43

GAD define

Answer 43

continous anxiety more than 6 months no stimulus

Question 44

screen for GAD?

Answer 44

GAD-7

Question 45

Define OCD?

Answer 45

Obsession: reccurent unwanted intrusive thoughts/images/impulses is one's mind despite resistance compulsion: repeated and seemingly purposeful rituals symptoms present more most days for >2weeks. Source of distress or interferece with activities

Question 46

define chorea?

Answer 46

jerky movements which move from one body area to another

Question 47

SSRI contradiction?

Answer 47

manic phase of bipolar affective disorder serotonin syndrome hyponatraemia

Question 48

what are the contraindication for clozapine

Answer 48

current or previous neutropenia previous myocarditis active or progressive liver disease

Question 49

how often are blood test done after starting clozapine

Answer 49

weekly- 18 weeks | 2weekly afterwards for a year then monthly

Question 50

what social factor can lower clozapine level?

Answer 50

smoking

Question 51

side effect of clozapine?

Answer 51

metabolic syndrome myocarditis lower seizure threshold hypersalivation - most common complaint

Question 52

treatment for tardive dyskinesia?

Answer 52

tetrabenazine

Question 53

What chemotherapy is used to manage ovarian cancer?

Answer 53

First line- paclitaxel + platinum based e.g. cisplatin/carboplatin Bevacizumab for advanced

Question 54

Which lymph nodes do vulval cancer spread to?

Answer 54

Inguinal lymph nodes