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years 5 > year 5 Drug list > Flashcards

year 5 Drug list Flashcards

1
Q

Donepezil

A

ACHe inhibtor, alzheimer + lewy body dementia

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2
Q

galantamine

A

ACHe inhibtor, alzheimer + lewy body dementia

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3
Q

rivastigmine

A

ACHe inhibtor, alzheimer + lewy body dementia

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4
Q

anti psychotic used for delirium?

A

Haloperidol- 1st line
risperidone
have low anti cholinergic effect

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5
Q

Ritalin(Methylphenidate)

A

ADHD stimulant

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6
Q

ADHD non stimulant drug

A

Atomoxetine

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7
Q

What are the side effects of ACHe?

A

GI upset
headaches
agitation
bradycardia

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8
Q

Memantine

A

non competitive glutamate receptor antagonist, for severe dementia or moderate if intolerance to ACHe inhibitors

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9
Q

lisdexamphetamine

A

adult ADHD stimulant drug

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10
Q

GDS?

A

gereatric depression scale

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11
Q

ACE?

A

adenbrook’s cognitive examination

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12
Q

First line SSRI for older adults?

A

mirtazapine, sertraline

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13
Q

medication for bipolar depression?

A

Quietiapine, lamotrigine

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14
Q

Antipsychotics for older adult schrizophrenia?

A

Amisulpride, olanzapine, risperidone

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15
Q

Examples of TCAs,
C
A
I

A

Clomipramine
Amitryptilline
Imipramine

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16
Q

MAOi example

A

seligine

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17
Q

What reaction can occur with seligine?

A

cheese reaction- high tyramine

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18
Q

Risperidone in depot form name?

A

Paliperidol

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19
Q

Examples of extrapyrimidal side effect?BOAT

A

Bradykinesia
Oculogyric crisis
Akathasia
Tardive dyskinesia

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20
Q

Management of oculogyric crisis?

A

IM procyclidine 5mg- hard to take oral in this state

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21
Q

what is a classic feature of serotonin syndrome comapared to NMS?

A

Myoclonus

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22
Q

what are the features of NMS?

A 
CK>1000
lecucytosis
high fever
muscle rigidity
palpitations
23
Q

what is the antidote of diazepam and benzodiazepine?

A

flumazenil

24
Q

therapeutic range of lithium?

A

0.4-1

25
Q

what needs to be monitored on lithium? BEETL

A 
(BMI
eGFR
Electrolytes 
Thyroid )- every 6 months
lithium level every 3 months
26
Q

If a patient with delirium tries to leave the ward, what should be filled out?

A

deprivation of liberty safegaurding form under MCA

27
Q

Which physical health can be treated under mental health act?

A

severe malnutriotion due to eating disorder

28
Q

treatment for methanol poisoning?

A

fomepizole

ethanol

29
Q

SSRI side effects? GASSd

A

Early: GI symptoms, anxiety, sleep disturbance (GASSd)
ongoing: sexual dysfunction

30
Q

Define perintal period?

A

pregnancy + 1 year after

31
Q

Scale for postnatal depression?

A

Edinbrugh postnatal depression scale

32
Q

safe SSRI for breastfeeding

A

setraline and paroxetine

33
Q

contraindicated SSRI for breastfeeding?

A

fluoxetine- long half life

34
Q

which anti emetic increases breast milk production?

A

metaclopramide

35
Q

SSRI contraindicated in pregnancy?

A

paroxetine

36
Q

What congenital abnormality is benzodiazepine associated with?

A

Cleft lip

37
Q

Most common side effect of lithium?

A

Tremor
Polydypsia
Polyuria
Weight gain

38
Q

Criteria for agoraphobia?

A 
anxiety due to 2 out of: 
crowds
public places
travelling alone
travelling away from home
39
Q

what substance might people with social phobia abuse?

A

alcohol

40
Q

management of phobias?

A

CBT 12 weeks with exposure therapy + breathing technique and other relaxation methods
Beta blockers
SSRI/SNRI

41
Q

define panic disorder

A

intermittent anxiety not triggered by a specific stimulus

42
Q

Investigation in panic disorder

A

alcohol withdrawal?
TFT
Urine drug screen
ECG

43
Q

GAD define

A

continous anxiety more than 6 months no stimulus

44
Q

screen for GAD?

A

GAD-7

45
Q

Define OCD?

A

Obsession: reccurent unwanted intrusive thoughts/images/impulses is one’s mind despite resistance
compulsion: repeated and seemingly purposeful rituals
symptoms present more most days for >2weeks. Source of distress or interferece with activities

46
Q

define chorea?

A

jerky movements which move from one body area to another

47
Q

SSRI contradiction?

A

manic phase of bipolar affective disorder
serotonin syndrome
hyponatraemia

48
Q

what are the contraindication for clozapine

A

current or previous neutropenia
previous myocarditis
active or progressive liver disease

49
Q

how often are blood test done after starting clozapine

A

weekly- 18 weeks

2weekly afterwards for a year then monthly

50
Q

what social factor can lower clozapine level?

A

smoking

51
Q

side effect of clozapine?

A

metabolic syndrome
myocarditis
lower seizure threshold
hypersalivation - most common complaint

52
Q

treatment for tardive dyskinesia?

A

tetrabenazine

53
Q

What chemotherapy is used to manage ovarian cancer?

A

First line- paclitaxel + platinum based e.g. cisplatin/carboplatin
Bevacizumab for advanced

54
Q

Which lymph nodes do vulval cancer spread to?

A

Inguinal lymph nodes

years 5 (4 decks)

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