Y4 - Substance Misuse Flashcards
Only includes information not in Y3 flashcards
1
Q
How does naltrexone work?
A
Competitive antagonist for opioid receptor
Blocks enjoyment from alcohol
2
Q
How does Acamprosate work?
A
Gaba agonist
Anticraving
3
Q
How does disulfiram work?
A
Deterrent
Acetyl aldehyde dehydrogenase inhibitor
Leads to build up of acetyl aldehyde which leads to hypertension, facial flushing, vomiting
Best given if supervised
4
Q
What things do you want to ask in a drug misuse history?
A
How much they use, money can be a good indication
How many times a day - gives idea of severity of use
How they take it
Where they inject (tend to start with arms –> legs –> groin –> neck (v. dangerous))
5
Q
What are the SEs of injecting drugs?
A
BBVs (HIV, HepB, HepC) Local infection/abscess Infective endocarditis Sepsis DVT/PE
6
Q
What drugs can be given to help people get off of heroin?
A
Methadone
Butamorphine
