Y4 - Mood Disorders Flashcards

Additional info only

1
Q

For which patients may mirtazapine be a good antidepressant?

A

Helps with anxiety symptoms, sleep and appetite

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2
Q

When do you know an antidepressant isn’t working?

A

If it doesn’t work after 8 weeks at the max/max tolerated dose

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3
Q

Define mania

A

Abnormally heightened mood associated with increased activity

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4
Q

In what context is mania usually seen?

A

BPAD or manic depression

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5
Q

How might someone with mania appear/behave?

A

Bizarrely dressed, inappropriate bright clothing
Animated, constantly moving
Overfamiliar, disinhibited, distractible, may become aggressive

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6
Q

How might someone’s speech and thought form be if they are manic?

A

Rapid, pressured, punning, clang associations

Flight of ideas

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7
Q

How might a manic person’s mood be?

A

Elated, irritable, angry

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8
Q

What may be included in a manic person’s thought content?

A

Unrealistic preoccupations, optimistic schemes

If psychotic may have grandiose/religious delusions

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9
Q

How might a manic person’s perceptions differ?

A

Mood-congruent hallucinations

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10
Q

How are the insight, judgement and cognition impacted in mania?

A

Insight and judgement very poor

Cognition usually unaffected

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11
Q

What investigations should you do in mania?

A

Collateral hx
Review old notes
Urine for drugs, glucose, UE, FBC, TFT

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12
Q

What are the classifications of mania?

A

Hypomania
Mania
Mania with psychotic features

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13
Q

What are the aetiologies of mania?

A

Biological, strong FH of BPAS/depressive disorder
Life events little relationship to onset
Organic causes, e.g. child birth, steroids, thyrotoxicosis

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14
Q

How common is mania?

A

1% of population

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15
Q

What is the proposed pathology behind mania?

A

Monoamine dysfunction

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16
Q

What are the complications of mania?

A

Suicide (15%)
Relationship problems
Loss of reputation, job
Consequences of risky behaviours (STIs, trauma, debts)

17
Q

What are some differentials for mania?

A
Normal emotional reaction 
Schizophrenia
Mood disorder
Anxiety disorder
Endocrine: hyperthyroidism, excessive steroids
Medication and substance use
Cerebral infection/infarction/trauma/tumour/temporal lobe epilepsy 
Neoplasm
18
Q

What is the management of mania?

A

Acute - sedatives (e.g. benzos), antipsychotics and mood stabilisers

Long term - lithium, anticonvulsants, antipsychotics, antidepressants

19
Q

What is poor prognosis in mania linked to?

A

Duration, severity, time, frequency, time to effective treatment, psychological dysfunction/PD, substance use

20
Q

What is bipolar disorder?

A

At least two episodes of hypomania/mania and depression

21
Q

How long do manic episodes tend to last for?

A

Anywhere between 2 weeks and 4-5 months

Median: 4 months