xerostomia drugs Flashcards

1
Q

cevimeline moa

A

muscarinic agonist with M3 specificity

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2
Q

cevimeline and pilocarpine contraindications

A

asthma, glaucoma, iritis

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3
Q

pilocarpine moa

A

nonspecific muscarinic agonist

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4
Q

cevimeline precautions

A

angina, breastfeeding, bronchitis, arrhythmias, cardiac disease, cholelithiasis, COPD, MI nephrolithiasis, and pregnancy, pediatric and geriatric patients

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5
Q

pilocarpine precautions

A

angina, breastfeeding, bronchitis, arrhythmias, cardiac disease, cholelithiasis, COPD, MI nephrolithiasis, and pregnancy and psychosis

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6
Q

muscarinic agonist for xerostomia with CNS activity

A

pilocarpine

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7
Q

amifostine moa

A

acts as a free radical scavenger and is used for protection during radiation treatments of head and neck cancer to prevent xerostomia

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8
Q

amifostine adverse effects

A

n/v, hypotension, and allergic reactions

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9
Q

labeled drug for hypersalivation

A

glycopyrrolate

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10
Q

off label drugs for hypersalivation

A

botox and scopolamine

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11
Q

glycopyrrolate moa

A

muscarinic antagonist, dries secretions in mouth and bronchial system

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