xerostomia drugs Flashcards
cevimeline moa
muscarinic agonist with M3 specificity
cevimeline and pilocarpine contraindications
asthma, glaucoma, iritis
pilocarpine moa
nonspecific muscarinic agonist
cevimeline precautions
angina, breastfeeding, bronchitis, arrhythmias, cardiac disease, cholelithiasis, COPD, MI nephrolithiasis, and pregnancy, pediatric and geriatric patients
pilocarpine precautions
angina, breastfeeding, bronchitis, arrhythmias, cardiac disease, cholelithiasis, COPD, MI nephrolithiasis, and pregnancy and psychosis
muscarinic agonist for xerostomia with CNS activity
pilocarpine
amifostine moa
acts as a free radical scavenger and is used for protection during radiation treatments of head and neck cancer to prevent xerostomia
amifostine adverse effects
n/v, hypotension, and allergic reactions
labeled drug for hypersalivation
glycopyrrolate
off label drugs for hypersalivation
botox and scopolamine
glycopyrrolate moa
muscarinic antagonist, dries secretions in mouth and bronchial system