Wrong Answers Flashcards

1
Q

process for post menopausal bleed

A

over 55y. endometrial TVUSS thickness over 5mm –> hysteroscopy with endometrial biopsy

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2
Q

where does lymph from scrotum go

A

inguinal nodes

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3
Q

mastitis caused by which bug. treatment

A

staph aureus

flucloxacillin

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4
Q

where does lymph from testes go

A

para-aortic

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5
Q

where does L/R testicular vein drain to

A

L: L renal vein
R: IVC

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6
Q

name 3 factors associated with small for gestational age

A

smoking
old age
maternal rubella

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7
Q

which ligament contains ovarian vessels

A

suspensory

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8
Q

name 3 hormones from posterior pituitary

A

LH
FSH
prolactin

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9
Q

causes of folate deficiency

A

phenytoin
methotrexate
pregnancy
alcohol excess

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10
Q

what hormone is responsible for low blood pressure in pregnancy and increased tidal volume

A

progesterone

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11
Q

menopause hormones

A

high FSH
high LH
low oestrogen `

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12
Q

name 2 risk factors for ectopic pregnancy

A

PID

endometriosis

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13
Q

what is released by sperm to prevent polyspermy

A

calcium

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14
Q

what role does beta hCG play

A

maintains corpus luteum

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15
Q

which cells of pre-antral follicle have LH receptors

A

theca

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16
Q

what converts androstenedione to oestradiol

A

aromatase in granulosa

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17
Q

where is the site of highest resistance in CVS

A

arterioles

contribute most to TPR

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18
Q

what type of fibres in vagus nerve

what neurotransmitter does it release

A

parasympathetic

Ach

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19
Q

what neurotransmitter released from sympathetic fibres

A

NA and adrenaline

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20
Q

what receptors does NA bind to in heart

A

beta 1 receptors in SAN (to increase rate of pacemaker depol)

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21
Q

2 locations of baroreceptors what are they stimulated by

A

aortic arch
carotid sinus

stimulated by arterial stretch

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22
Q

symptoms of kawasaki

A

bilateral conjunctivitis
rash
desquamation of palsm/soles

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23
Q

toxic shock syndrome caused by which toxin in bacteria

A

toxin 1 in staph aureus

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24
Q

anterior is which leads

A

V2-6

25
Q

CXR obscured hemidiaphragm and tracheal shift away from affected side

A

pleural effusion

26
Q

reduced breath sounds, hyper-resonant percussion.

CXR: no vascular markings

A

pneumothorax

27
Q

widened mediastinum

A

aortic dissection

28
Q

treatment of type A and B aortic dissection

A

A: surgery, control BP 100
B: conservative, bed rest, reduce BP, IV labetolol

29
Q

what is substance P

A

a neuroT with a neurokinin R1 - affects behaviour and response to stress

30
Q

what does nicotinic acid treat

A

hyperlipidaemia (lowers chol and TG conc)

31
Q

SE of nicotinic acid

A

flush, impaired gluc tolerance, myositis

32
Q

2 drugs you give to someone with PVD

A

statin

clopidogrel

33
Q

what is doxazosin

A

alpha 1 blocker -> smooth muscle relaxation

34
Q

which drugs worsen intermittent claudication

A

beta blockers

35
Q

2 things that increase pulse pressure

A

less compliant aorta

increased SV

36
Q

thiazide diuretics SE

A

dehydration, postural hypotension, hyponatraemia, hypoK, hyperCa, gout, impaired gluc tolerance

37
Q

3 clinical features of aortic dissection

A

tearing chest pain
hypertension
aortic regurgitation

38
Q

Cardiac defect associated with trisomy 13

A

patau

ventricular septal defect –> pansystolic murmur

39
Q

Cardiac defect associated with trisomy 21

A
  • AV septal defects
40
Q

Cardiac defect associated with 45XO

A

turner: bicuspid aorta, coarctation of aorta

41
Q

Cardiac defect associated with diabetic mother

A

transposition of great vessels, VSD

42
Q

Cardiac defect associated with DiGeorge syndrome

A

DiGeorge - truncus arteriorsis, tetralogy of fallot

43
Q

Cardiac defect associated with marfans

A

coarctation of aorta

44
Q

what is Ebstein’s anomaly

A

tricuspid valve displaced towards apex of RV. Maternal lithium is a RF.

45
Q

ACA supplies what

A

frontal

parietal

46
Q

MCA supplies what

A

frontal, temporal, parietal

47
Q

lateral heart which leads

A

lead I, II, aVL, V5-6

48
Q

what ECG changes in LBBB

A

W in V1 and M in V6

49
Q

what ECG changes in RBBB

A

M in V1 ad W in V6

50
Q

causes of RBBB

A

chronically increased RV pressure, MI, ASD, cardiomyopathy

51
Q

where do thiazide diuretics act

A

NaCl symporter at DCT

52
Q

Side effects of Metformin

A

GI upset, AKI (CI if eGFR <30)

53
Q

Side effects of sulphonylureas

A

hypoglycaemia, weight gain

54
Q

Side effects of DPP4I

A

GI upset, weight loss

55
Q

Side effects of SGLT2I

A

UTI, thrush, euglycaemic DKA

56
Q

left flank pain, chronic HTN, purple mottled rash on lower legs, haematuria and +protein.
Platelet 84 and raised APTT
Which antibody tests?

A

anti-cardiolipin, lupus anticoagulat, beta-2 glycoprotein 1 (SLE)
ANTI-PHOSPHOLIPID SYND
- pain due to renal vein thrombosus (if young F think ectopic)
- autoimmune hypercoagulable state
- confirm: one clinical event (thrombosis or pregnancy complication) with TWO + antibody tests 12 weeks apart

57
Q

Features of anti-phospholipid syndrome

A

Coagulopathy (increased APTT)
Livedo reticularis (purple mottled rash)
Obstetric (ectopics, recurrent miscarriages)
Thrombocytopenia

58
Q

How do you confirm Antiphospholipid syndrome

A

one clinical event (thrombosis or pregnancy complication) with TWO + antibody tests 12 weeks apart

59
Q

Treating anti-phospholipid syndrome

A

anticoag (warfarin ONLY if triple antibody)

pregnant: LMWH and low dose aspirin