Chris Isles Flashcards
Questions to ask jaundiced
- itch (cholestasis)
- dark urine
- pale stools
- pain? (gallstones, cholangitis)
- weight loss
(pancreatic cancer) - blood transfusion
(HBV, HCV) - foreign travel
(HAV) - medications
- alcohol intake
- occupation
Stigmata of chronic liver disease
spider nevi palmar erythema dupuytren's gynaecomastia loss of body hair parotid swelling testicular atrophy
Signs of portal hypertension
ascites
splenomegaly
distended abdominal veins
Signs of hepatic encephalopathy
Confusion
Flap (asterixis)
Hepatic fetor
Constructional apraxia
Other signs to look for in jaundiced patient
pallor (haemolytic anaemia) weight loss scratch marks (obstructive jaundice) tattoos/body piercing/needle tracks urine and stools (pale urine, dark stools) palpable gall bladder
Courvoisier’s law
palpable gallbladder doesn’t mean gallstones - suggests pancreatic cancer
Murphy’s sign suggests what
acute cholecystitis
- take deep breath in while palpating subcostal area.
pain on INSPIRATION
Troisier’s sign
intra-abdominal malignancy
- hard left supraclavicular node (Virchow’s node)
Investigations for jaundice
abdo USS *
Routine bloods
Viral studies
5 commonest causes of hepatomegaly
in UK: cardiac failure fatty liver (alcoholic or NASH) early cirrhosis cancer (liver secondaries) infections (HAV, EBV)
Causes of hepatomegaly (give more than 5)
cardiac failure fatty liver (alcoholic, NASH) early cirrhosis cancer infections Other chronic liver disease (PBC, PSC, CAH, Hep) myeloproliferative (CML) Lymphoproliferative (CLL, lymphoma)
Describing hepatomegaly
Size
Consistency (soft, firm, hard)
Surface - smooth or irregular
Tender - heart failure, hepatitis
Causes of splenomegaly
CML Myelofibrosis Malaria Kala-azar Gaucher's disease
How to tell whether you can feel spleen or kidney?
spleen might have a notch
kidney is ballotable
spleen dull to percuss, kidney band of resonance
spleen enlarges to RIP, kidney moves down on insp
Causes of hepatosplenomegaly (and what would you look for?)
Myeloproliferative - pallor, purpura)
Lymphoproliferative (lymph nodes)
Cirrhosis with portal HTN (signs of chronic liver disease)