Wound Healing Flashcards
1
Q
Physiologic events
A
Vascular constriction
Platelet plug formation
Fibrin formation
Fibrinolysis
2
Q
Vasoconstrictors
A
Txa2 Endothelin Serotonin Bradykinin Histamine
3
Q
Chemotactic factors
A
PDGF TGF B PAF Fibronectin Serotonin
4
Q
How many minutes does first phase of wound healing begin
A
3-5 minutes
7 minutes maximum
5
Q
What are the last cell population to invade the wound
A
Fibroblast
endothelial cells
6
Q
Potent chemotactic agent
A
PDGF
7
Q
Potent regulator of collagen synthase
A
Lactate
8
Q
Makes up granulation tissue
A
Proteoglycan
9
Q
Major Gags found in wounds
A
Dermatan
Chondroitin sulphate
10
Q
What breaks down collagen
A
MMP
11
Q
Strongest layer in the GIT
A
Submucosa
12
Q
Antagonizes the effect of steroid drugs
A
Vitamin A
13
Q
Ideal time to give chemo drugs after surgery
A
2 weeks -
4 weeks - practice
14
Q
How many grams of vitamin C can be used to increase collagen synthesis
A
2g
