Worksop 1.1 CV Simulation: Drugs Used In CVD Flashcards
What is total peripheral resistance a function of?
- Viscosity of blood (haematocratic)
- Length of blood vessels
- Blood vessel luminal diameter
What are the two adrenergic receptors?
- Alpha receptors
- Beta receptors
What does alpha 1 receptor do?
Contraction of vascular smooth muscle
What does alpha 2 receptor do?
Contraction of vascular smooth muscle
What does beta 1 receptor do?
Positive Inotropic and Chronotropic effects on the heart
What does beta 2 receptor do?
Relaxes vascular smooth muscle
What controls long term blood pressure?
Renin angiotensin aldosterone system
Does phenylephrine have effects on beta receptors?
No
What is the side effect of an ACE inhibitor?
Dry cough
What should you do with a patients medication if they are on an ACE inhibitor and develop a dry cough?
- ACE inhibitor is stopped
- Given an ARB instead
How do ACE inhibitors cause a cough?
Increase release of bradykinin
How does nitric oxide control blood pressure?