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3.23 > Lab 5 – The pharmacist prescriber’s role in anticoagulation and counselling > Flashcards

Lab 5 – The pharmacist prescriber’s role in anticoagulation and counselling Flashcards

1
Q

What is venostasis?

A

When blood is not moving

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2
Q

What causes venostasis?

A
  • Post surgery
  • Immobility
  • Bed rest
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3
Q

What is endothelial trauma?

A

Damage to blood vessels caused by injury

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4
Q

What is hypercoagulability?

A

Increased coagulation

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5
Q

What causes hypercoagulability?

A
  • Dehydration
  • Age (natural anticoagulating factors reduce – antithrombin III, protein C and S)
  • Hyperhomocysteinemia
  • Elevated factor VIII
  • Malignancy
  • Dysfibrinolysis
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6
Q

What is a pulmonary embolism?

A

Blocked blood vessel in the lung

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7
Q

What is the clotting test?

A

Asseses how well a patients blood clots

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8
Q

What is International normalised ratio (INR)?

A

Measures the time for blood to clot - only relevant for warfarin not DOACs

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9
Q

What is given to patients who decline anticoagulant treatment?

A

Aspirin 75mg or 150mg daily - not to be used for secondary prevention of DVT or PE

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10
Q

What are the current anticoagulation therapies?

A
  • Unfractionated heparin
  • Warfarin
  • DOACs
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11
Q

When is fondaparinux used

A

Acute coranary syndrome

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12
Q

What is the most widely used oran anticoagulant?

A

Warfarin

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13
Q

How does warfarin work?

A

Inhibits synthesis of vitamin K dependant clotting factors II, VII, IX, X

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14
Q

What is fennerty?

A

Age adgustment dose for warfarin

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15
Q

What is dabigatran?

A

Direct thrombin inhibitor

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16
Q

What are the direct factor Xa inhibitors?

A
  • Edoxaban
  • Apixaban
17
Q

What are the advantages of DOACs

A
  • No bridging required (dont need to stop tablet before startong another one)
  • Fewer interactions
  • Convenient for patients
18
Q

What are the disadvantages of DOACs?

A
  • Lack of monitoring
  • Patients may miss doses
  • GI side effects
  • Compliance
19
Q

What are the treatment options for DVT?

A
20
Q

Why is warfarin given at 6pm?

A
  • Incase the dose needs to be changed
  • So its taken at the same time everyday

3.23 (26 decks)

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