womens health 1 Flashcards
what is Hydroxyprogesterone?
- An androgen
what is androstenedione?
- An androgen
what is estrone?
- Estrogen
Estrogen response elements, androgen response lelement and progesterone response element regulate gene transcription. TRUE OR FLASE?
TRUE
Estrogen acts a signalling molecule by binding to specific target cells. TRUE OR FALSE?
TRUE
what are ER used in?
- Contraception
- Pre and post menopause prblems (HRT)
- treatment of breast cancer
ER acts a signalling molecule for heart, breast, liver. true or false?
true
the receptor undergoes dimerization in order for it to increase affinity for the EREs and regulate gene expression. TRUE OR FALSE?
TRUE
What do progestins do?
- Interact with PR and mimic the stimulatory effecst of progesterone
Mifeprestone is a PR antagonist. TRUE OR FLASE?
TRUE
Mifeprestone is used to terminate pregnancy. TRUE ORF ALSE?
TRUE
Theca secretes testosterone
Antrum contains estrogen
Granulosa converts testosterone to estrogen. TRUE OR FALSE?
TRUE
FSH stimulates several follicle release and secretion of estradiol. TRUE OR FALSE?
TRUE
Folicles causes low levels of estradiol which leads to endometrial contraction leading to menstration, here LH is inhibited and FSH is stimulated. TRUE OR FLASE?
TRUE
FSH and LH are released from pituitary. TRUE OR FLASE?
TRUE